SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4psm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CP4_A_CAMA422_0 (CYTOCHROME P450CAM)	4psm	SSDNA BINDING PROTEIN (Pyrococcus furiosus)	5 / 9	LEU A 42 VAL A 18 THR A 6 VAL A 61 VAL A 9	None	1.41A	5cp4A-4psmA: undetectable	5cp4A-4psmA: 17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JSD_B_1GNB603_1 (PHIAB6 TAILSPIKE)	4psm	SSDNA BINDING PROTEIN (Pyrococcus furiosus)	3 / 3	VAL A 61 GLU A 105 GLU A 102	None	0.90A	5jsdB-4psmA: undetectable 5jsdC-4psmA: undetectable	5jsdB-4psmA: 12.99 5jsdC-4psmA: 12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_A_CELA602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4psm	SSDNA BINDING PROTEIN (Pyrococcus furiosus)	4 / 6	VAL A 9 LEU A 22 ILE A 74 PHE A 67	None	1.07A	5jw1A-4psmA: undetectable	5jw1A-4psmA: 14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JW1_B_CELB602_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4psm	SSDNA BINDING PROTEIN (Pyrococcus furiosus)	4 / 6	VAL A 9 VAL A 21 ILE A 74 PHE A 67	None	1.04A	5jw1B-4psmA: undetectable	5jw1B-4psmA: 14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AZ3_1_PAR11803_1 (RRNA ALPHA RIBOSOMAL PROTEIN EL18)	4psm	SSDNA BINDING PROTEIN (Pyrococcus furiosus)	3 / 3	SER A 126 LYS A 127 SER A 130	None	0.72A	6az3P-4psmA: undetectable	6az3P-4psmA: 19.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5CP4_A_CAMA422_0","CYTOCHROME P450CAM","4psm","SSDNA BINDING PROTEIN","Pyrococcus furiosus",5,"LEU A  42;VAL A  18;THR A   6;VAL A  61;VAL A   9","None","1.41A","5cp4A-4psmA:undetectable","5cp4A-4psmA:17.98"],["5JSD_B_1GNB603_1","PHIAB6 TAILSPIKE;PHIAB6 TAILSPIKE","4psm","SSDNA BINDING PROTEIN","Pyrococcus furiosus",3,"VAL A  61;GLU A 105;GLU A 102","None","0.90A","5jsdB-4psmA:undetectable;5jsdC-4psmA:undetectable","5jsdB-4psmA:12.99;5jsdC-4psmA:12.99"],["5JW1_A_CELA602_2","PROSTAGLANDIN G\/H SYNTHASE 2","4psm","SSDNA BINDING PROTEIN","Pyrococcus furiosus",4,"VAL A   9;LEU A  22;ILE A  74;PHE A  67","None","1.07A","5jw1A-4psmA:undetectable","5jw1A-4psmA:14.39"],["5JW1_B_CELB602_2","PROSTAGLANDIN G\/H SYNTHASE 2","4psm","SSDNA BINDING PROTEIN","Pyrococcus furiosus",4,"VAL A   9;VAL A  21;ILE A  74;PHE A  67","None","1.04A","5jw1B-4psmA:undetectable","5jw1B-4psmA:14.39"],["6AZ3_1_PAR11803_1","RRNA ALPHA;RIBOSOMAL PROTEIN EL18","4psm","SSDNA BINDING PROTEIN","Pyrococcus furiosus",3,"SER A 126;LYS A 127;SER A 130","None","0.72A","6az3P-4psmA:undetectable","6az3P-4psmA:19.59"]]