SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4psp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 7 HIS A 127
HIS A 126
HIS A 171
TRP A 224
 None
GOL  A 622 (-3.3A)
GOL  A 622 (-4.2A)
GOL  A 622 (-4.5A)
 0.84A 1am6A-4pspA:
undetectable		 1am6A-4pspA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 8 HIS A 127
HIS A 126
HIS A 171
TRP A 224
 None
GOL  A 622 (-3.3A)
GOL  A 622 (-4.2A)
GOL  A 622 (-4.5A)
 0.86A 1azmA-4pspA:
undetectable		 1azmA-4pspA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 8 HIS A 127
HIS A 126
HIS A 171
TRP A 224
 None
GOL  A 622 (-3.3A)
GOL  A 622 (-4.2A)
GOL  A 622 (-4.5A)
 0.85A 1bzmA-4pspA:
undetectable		 1bzmA-4pspA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		3 / 3 TRP A 155
VAL A 123
TRP A  35
 None
 1.08A 1c4dA-4pspA:
undetectable
1c4dB-4pspA:
undetectable		 1c4dA-4pspA:
2.60
1c4dB-4pspA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		3 / 4 VAL A  31
TRP A 224
TRP A  33
 None
GOL  A 622 (-4.5A)
None
 1.45A 1gmkC-4pspA:
undetectable
1gmkD-4pspA:
undetectable		 1gmkC-4pspA:
2.60
1gmkD-4pspA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 7 GLY A 370
LEU A 451
LYS A 488
TYR A 417
 None
 0.94A 1gtiD-4pspA:
undetectable		 1gtiD-4pspA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 7 GLY A 370
LEU A 451
LYS A 488
TYR A 417
 None
 0.93A 1gtiE-4pspA:
undetectable		 1gtiE-4pspA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 TYR A   7
GLU A 261
PHE A 278
LEU A 229
PHE A 252
 None
 1.25A 1nw3A-4pspA:
undetectable		 1nw3A-4pspA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 6 ASP A 275
TYR A 271
ASP A 285
ASN A 280
 None
TRS  A 617 (-3.5A)
TRS  A 617 (-2.7A)
NAG  A 601 ( 1.8A)
 1.15A 1rjdA-4pspA:
undetectable		 1rjdA-4pspA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 6 ASP A 275
TYR A 271
ASP A 285
ASN A 280
 None
TRS  A 617 (-3.5A)
TRS  A 617 (-2.7A)
NAG  A 601 ( 1.8A)
 1.15A 1rjdB-4pspA:
undetectable		 1rjdB-4pspA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 6 ASP A 275
TYR A 271
ASP A 285
ASN A 280
 None
TRS  A 617 (-3.5A)
TRS  A 617 (-2.7A)
NAG  A 601 ( 1.8A)
 1.17A 1rjdC-4pspA:
undetectable		 1rjdC-4pspA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 6 GLU A 531
ASP A 525
PHE A 556
ARG A 557
 None
NAG  A 601 ( 4.9A)
None
NAG  A 601 (-3.1A)
 1.39A 2a3bB-4pspA:
9.7		 2a3bB-4pspA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 7 TRP A 287
GLY A 337
ASP A 303
THR A 270
 None
None
GOL  A 622 (-2.6A)
None
 1.15A 2aouB-4pspA:
undetectable		 2aouB-4pspA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 8 HIS A 127
HIS A 126
HIS A 171
TRP A 224
 None
GOL  A 622 (-3.3A)
GOL  A 622 (-4.2A)
GOL  A 622 (-4.5A)
 0.89A 2gehA-4pspA:
undetectable		 2gehA-4pspA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 11 LEU A 483
ILE A 362
ALA A 324
LEU A 341
ASP A 304
 None
 1.19A 2q72A-4pspA:
undetectable		 2q72A-4pspA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 10 LEU A 151
LEU A 149
LEU A  96
LYS A  97
LEU A 154
 None
 1.17A 2xn6A-4pspA:
undetectable
2xn6B-4pspA:
undetectable		 2xn6A-4pspA:
22.17
2xn6B-4pspA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		3 / 3 HIS A  34
HIS A 171
HIS A 126
 GOL  A 622 (-3.6A)
GOL  A 622 (-4.2A)
GOL  A 622 (-3.3A)
 0.74A 3ag4A-4pspA:
undetectable		 3ag4A-4pspA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		3 / 3 TYR A   7
GLU A 266
ASP A  26
 None
 0.85A 3bxoA-4pspA:
undetectable		 3bxoA-4pspA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		3 / 3 TYR A   7
GLU A 266
ASP A  26
 None
 0.87A 3bxoB-4pspA:
undetectable		 3bxoB-4pspA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		3 / 3 ASN A 138
ASN A 175
GLU A 203
 None
 0.92A 3kpdB-4pspA:
undetectable		 3kpdB-4pspA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 PRO A 479
LEU A 450
VAL A 418
VAL A 429
TYR A 485
 None
None
None
TRS  A 618 (-3.9A)
None
 1.46A 3meeA-4pspA:
undetectable		 3meeA-4pspA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 6 PHE A 365
LEU A 421
ALA A 372
THR A 408
LEU A 329
 None
 1.47A 3t3zA-4pspA:
undetectable		 3t3zA-4pspA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 6 PHE A 365
LEU A 421
ALA A 372
THR A 408
LEU A 329
 None
 1.48A 3t3zB-4pspA:
undetectable		 3t3zB-4pspA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 6 PHE A 365
LEU A 421
ALA A 372
THR A 408
LEU A 329
 None
 1.47A 3t3zD-4pspA:
undetectable		 3t3zD-4pspA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 8 HIS A 127
HIS A 126
HIS A 171
TRP A 224
 None
GOL  A 622 (-3.3A)
GOL  A 622 (-4.2A)
GOL  A 622 (-4.5A)
 0.88A 3w6hA-4pspA:
undetectable		 3w6hA-4pspA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 7 TRP A 311
ILE A 343
PHE A  29
ASP A 286
 GOL  A 622 ( 2.8A)
None
None
None
 1.33A 4iarA-4pspA:
undetectable		 4iarA-4pspA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 ASN A 433
LEU A 471
VAL A 429
ILE A 473
LEU A 450
 None
None
TRS  A 618 (-3.9A)
None
None
 1.47A 4k36A-4pspA:
2.0		 4k36A-4pspA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 ASN A 433
LEU A 471
VAL A 429
ILE A 473
LEU A 450
 None
None
TRS  A 618 (-3.9A)
None
None
 1.44A 4k36B-4pspA:
4.1		 4k36B-4pspA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 11 ASN A 433
LEU A 471
VAL A 429
ILE A 473
LEU A 450
 None
None
TRS  A 618 (-3.9A)
None
None
 1.31A 4k37B-4pspA:
2.7		 4k37B-4pspA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 ASN A 433
LEU A 471
VAL A 429
ILE A 473
LEU A 450
 None
None
TRS  A 618 (-3.9A)
None
None
 1.33A 4k39A-4pspA:
2.9		 4k39A-4pspA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 1.10A 4mm4A-4pspA:
undetectable		 4mm4A-4pspA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 1.09A 4mm4B-4pspA:
undetectable		 4mm4B-4pspA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 9 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 1.10A 4mm5A-4pspA:
undetectable		 4mm5A-4pspA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 0.99A 4mm6A-4pspA:
undetectable		 4mm6A-4pspA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 1.16A 4mm8A-4pspA:
undetectable		 4mm8A-4pspA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 9 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 1.09A 4mmbA-4pspA:
undetectable		 4mmbA-4pspA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 10 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 0.98A 4mmdA-4pspA:
undetectable		 4mmdA-4pspA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 0.95A 4mmdB-4pspA:
undetectable		 4mmdB-4pspA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 9 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 1.00A 4mmeA-4pspA:
undetectable		 4mmeA-4pspA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 9 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 1.00A 4mmeB-4pspA:
undetectable		 4mmeB-4pspA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 9 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 0.99A 4mmfA-4pspA:
undetectable		 4mmfA-4pspA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 9 ASP A 303
VAL A 167
ALA A 120
TYR A  32
GLY A  30
 GOL  A 622 (-2.6A)
None
None
None
None
 1.01A 4mmfB-4pspA:
undetectable		 4mmfB-4pspA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 4 LEU A 198
SER A 190
LEU A 195
LEU A 206
 None
 1.03A 4n09A-4pspA:
3.6		 4n09A-4pspA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 5 LEU A 198
SER A 190
LEU A 195
LEU A 206
 None
 1.02A 4n09B-4pspA:
2.6		 4n09B-4pspA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 5 LEU A 198
SER A 190
LEU A 195
LEU A 206
 None
 1.04A 4n09D-4pspA:
2.9		 4n09D-4pspA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 6 MET A 170
ILE A 108
ILE A 109
VAL A 112
 None
 0.99A 4olmA-4pspA:
undetectable		 4olmA-4pspA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 8 SER A  45
SER A 307
ASP A 304
ASP A 303
 None
None
None
GOL  A 622 (-2.6A)
 1.29A 4qb9D-4pspA:
undetectable		 4qb9D-4pspA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 5 SER A 282
ARG A 259
GLY A 260
GLU A 262
 None
 1.13A 5cdqA-4pspA:
2.1
5cdqB-4pspA:
undetectable
5cdqC-4pspA:
undetectable		 5cdqA-4pspA:
22.06
5cdqB-4pspA:
16.34
5cdqC-4pspA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 5 SER A 282
ARG A 259
GLY A 260
GLU A 262
 None
 1.13A 5cdqR-4pspA:
undetectable
5cdqS-4pspA:
undetectable
5cdqT-4pspA:
undetectable		 5cdqR-4pspA:
22.06
5cdqS-4pspA:
16.34
5cdqT-4pspA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 5 SER A 310
GLN A 355
ILE A 317
TYR A 313
 None
 1.34A 5fuqA-4pspA:
1.6
5fuqB-4pspA:
2.0		 5fuqA-4pspA:
19.76
5fuqB-4pspA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 TYR A  75
THR A  40
THR A  39
ALA A  37
THR A  66
 None
 1.03A 5lf7V-4pspA:
undetectable
5lf7b-4pspA:
undetectable		 5lf7V-4pspA:
18.48
5lf7b-4pspA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		5 / 12 TYR A  75
THR A  40
THR A  39
ALA A  37
THR A  66
 None
 1.02A 5lf7H-4pspA:
undetectable
5lf7N-4pspA:
undetectable		 5lf7H-4pspA:
18.48
5lf7N-4pspA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 5 HIS A 570
ILE A 542
SER A 566
ALA A 504
 None
 1.17A 5msdA-4pspA:
undetectable		 5msdA-4pspA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 5 LEU A 340
MET A 325
GLN A 355
TYR A 319
 None
 1.43A 5uc3A-4pspA:
undetectable		 5uc3A-4pspA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 8 GLY A 236
GLU A 234
GLN A  59
TRP A 182
 None
 1.05A 5vlmD-4pspA:
undetectable		 5vlmD-4pspA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		3 / 3 HIS A  34
HIS A 171
HIS A 126
 GOL  A 622 (-3.6A)
GOL  A 622 (-4.2A)
GOL  A 622 (-3.3A)
 0.74A 6giqa-4pspA:
undetectable		 6giqa-4pspA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 4psp ALPHA-FUCOSIDASE
GH29
(Fusarium
graminearum) 		4 / 6 PRO A 142
ILE A  79
GLY A 146
TYR A 145
 None
 1.12A 6gqiA-4pspA:
undetectable		 6gqiA-4pspA:
23.09