SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4psu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		4 / 5 LEU A 135
LEU A 121
LEU A  74
GLY A 113
 None
 1.05A 1a4lC-4psuA:
undetectable		 1a4lC-4psuA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		3 / 3 TRP A  14
VAL A  32
TRP A   7
 None
 0.98A 1c4dA-4psuA:
undetectable
1c4dB-4psuA:
undetectable		 1c4dA-4psuA:
4.86
1c4dB-4psuA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 LEU A  59
ALA A  60
LEU A  45
PRO A  15
LEU A 198
 None
 1.22A 1og5A-4psuA:
undetectable		 1og5A-4psuA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		4 / 6 ALA A 289
TYR A  67
ILE A 285
ILE A 134
 None
 1.20A 2dcfA-4psuA:
undetectable		 2dcfA-4psuA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		4 / 7 SER A  55
HIS A 271
HIS A 274
TYR A 199
 None
None
None
12P  A 301 ( 4.7A)
 1.15A 2vmyA-4psuA:
undetectable
2vmyB-4psuA:
undetectable		 2vmyA-4psuA:
22.09
2vmyB-4psuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		4 / 8 TYR A 199
SER A  55
HIS A 271
HIS A 274
 12P  A 301 ( 4.7A)
None
None
None
 1.13A 2vmyA-4psuA:
undetectable
2vmyB-4psuA:
undetectable		 2vmyA-4psuA:
22.09
2vmyB-4psuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		4 / 7 ALA A 289
TYR A  67
ILE A 285
ILE A 134
 None
 1.18A 2zm7A-4psuA:
undetectable		 2zm7A-4psuA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 SER A  55
HIS A 114
LEU A  45
VAL A  69
LEU A 272
 None
 1.21A 3g9eA-4psuA:
undetectable		 3g9eA-4psuA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 117
HIS A  77
LEU A 138
SER A 137
HIS A 271
 None
 1.31A 3pfgA-4psuA:
2.2		 3pfgA-4psuA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 8 GLY A 270
SER A 189
ILE A 191
SER A  55
ASP A 243
 None
 1.41A 3pwwA-4psuA:
undetectable		 3pwwA-4psuA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_D_VK3D202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		4 / 5 TRP A  14
ARG A  57
TYR A 199
LEU A 202
 None
None
12P  A 301 ( 4.7A)
None
 1.49A 4f8yC-4psuA:
3.3
4f8yD-4psuA:
2.2		 4f8yC-4psuA:
23.20
4f8yD-4psuA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 HIS A 208
HIS A 274
HIS A 114
GLY A  48
TYR A 199
 None
None
None
None
12P  A 301 ( 4.7A)
 1.01A 4lxzA-4psuA:
undetectable		 4lxzA-4psuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 SER A  55
HIS A 114
LEU A  45
VAL A  69
LEU A 272
 None
 1.27A 4o8fB-4psuA:
undetectable		 4o8fB-4psuA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 HIS A  31
PHE A  22
LEU A 202
ASP A  73
SER A  53
 None
 1.45A 4r88C-4psuA:
3.0		 4r88C-4psuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 HIS A  31
PHE A  22
LEU A 202
ASP A  73
SER A  53
 None
 1.48A 4r88D-4psuA:
2.9		 4r88D-4psuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 HIS A  31
PHE A  22
LEU A 202
ASP A  73
SER A  53
 None
 1.45A 4r88E-4psuA:
3.0		 4r88E-4psuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		5 / 12 HIS A  31
PHE A  22
LEU A 202
ASP A  73
SER A  53
 None
 1.42A 4r88F-4psuA:
3.0		 4r88F-4psuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		4 / 6 ARG A  34
HIS A  68
LEU A  44
PRO A  72
 None
 1.39A 5syjA-4psuA:
undetectable		 5syjA-4psuA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 4psu ALPHA/BETA HYDROLASE
(Rhodopseudomonas
palustris) 		4 / 6 ARG A  34
HIS A  68
LEU A  44
PRO A  72
 None
 1.38A 5syjB-4psuA:
undetectable		 5syjB-4psuA:
20.33