SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4psw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 11 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.13A 1fkfA-4pswA:
undetectable		 1fkfA-4pswA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 11 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.13A 1fkjA-4pswA:
undetectable		 1fkjA-4pswA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.44A 1gtnO-4pswB:
undetectable
1gtnP-4pswB:
undetectable		 1gtnO-4pswB:
12.07
1gtnP-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
HISTONE H4 TYPE VIII
(Saccharomyces
cerevisiae;
Ophiophagus
hannah) 		3 / 3 GLU B  13
LYS C  46
VAL C  45
 None
 0.92A 1l2iA-4pswB:
undetectable		 1l2iA-4pswB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 12 VAL A  69
ILE A  54
SER A  22
TYR A  66
VAL A  96
 None
 1.13A 1s19A-4pswA:
undetectable		 1s19A-4pswA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 11 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.26A 1tcoC-4pswA:
undetectable		 1tcoC-4pswA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 ARG B 352
TYR B  14
LYS B  18
 None
 0.99A 1uujB-4pswB:
undetectable		 1uujB-4pswB:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 6 LEU B 257
GLY B 225
ILE B 211
HIS B 207
 None
 0.92A 1yajF-4pswB:
undetectable		 1yajF-4pswB:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 11 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.17A 1yatA-4pswA:
undetectable		 1yatA-4pswA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFM_B_TOPB1290_1
(PTERIDINE REDUCTASE
1)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 9 PHE A 205
LEU B 288
TYR A 199
LEU B 267
LEU B 281
 None
 1.31A 2bfmB-4pswA:
0.0
2bfmC-4pswA:
0.0		 2bfmB-4pswA:
20.12
2bfmC-4pswA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 11 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.14A 2fkeA-4pswA:
undetectable		 2fkeA-4pswA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 MET B 321
VAL B  28
GLU B 372
 None
 0.91A 2x9gA-4pswB:
undetectable		 2x9gA-4pswB:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 5 ILE A 155
PHE A 223
PRO A  65
VAL A 124
 None
 1.00A 2ygnA-4pswA:
undetectable		 2ygnA-4pswA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 6 TYR A  71
VAL A  83
VAL A  98
VAL A  67
 None
 0.94A 2z97A-4pswA:
undetectable		 2z97A-4pswA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 188
PHE A  31
PHE A 160
GLY A 232
 None
None
None
COA  A 401 (-3.3A)
 0.86A 3em0B-4pswA:
1.8		 3em0B-4pswA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 12 VAL B 311
SER B 313
ALA B 258
LEU B 267
LEU B 266
 None
 1.05A 3hs6A-4pswB:
undetectable		 3hs6A-4pswB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 10 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.18A 3ihzA-4pswA:
undetectable		 3ihzA-4pswA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 11 ILE B  60
PHE B  75
ILE B 133
ALA B 124
PRO B  44
 None
 0.83A 3tmzA-4pswB:
undetectable		 3tmzA-4pswB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  88
ILE A  46
ILE A  54
VAL A  67
LEU A  56
 None
 1.07A 3w67B-4pswA:
undetectable		 3w67B-4pswA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 TYR A  49
ASP A  82
ASP A  78
 None
 0.84A 4a6eA-4pswA:
2.0		 4a6eA-4pswA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  91
LEU A  87
ILE A 155
VAL A  67
GLY A  25
 None
 0.71A 4an2A-4pswA:
undetectable		 4an2A-4pswA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
HISTONE H4 TYPE VIII
(Ophiophagus
hannah;
Saccharomyces
cerevisiae) 		4 / 5 LEU B 344
ASP B 339
ARG C  42
ARG C  41
 None
 1.32A 4cpzA-4pswB:
9.5		 4cpzA-4pswB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 221
ILE A  23
GLY A 189
PHE A  63
 COA  A 401 ( 4.6A)
None
None
None
 1.06A 4dc3A-4pswA:
undetectable		 4dc3A-4pswA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 11 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.20A 4dz2A-4pswA:
undetectable
4dz2B-4pswA:
undetectable		 4dz2A-4pswA:
16.88
4dz2B-4pswA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 10 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.23A 4dz3A-4pswA:
undetectable		 4dz3A-4pswA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 10 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.25A 4dz3B-4pswA:
undetectable		 4dz3B-4pswA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 267
TYR A 278
ASN A 318
 COA  A 401 (-3.2A)
None
None
 0.87A 4ffwB-4pswA:
2.5		 4ffwB-4pswA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
HISTONE H4 TYPE VIII
(Saccharomyces
cerevisiae;
Ophiophagus
hannah) 		4 / 8 GLY C  15
GLY C   9
TYR B 275
VAL B 341
 None
 0.86A 4fgzB-4pswC:
undetectable		 4fgzB-4pswC:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  71
VAL A  83
VAL A  98
VAL A  67
 None
 0.77A 4l4bA-4pswA:
undetectable		 4l4bA-4pswA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 7 PHE B 259
LEU B 267
LEU B 233
ASP B 213
 None
 0.79A 4rmjA-4pswB:
undetectable		 4rmjA-4pswB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 GLU A 304
ARG A 297
GLN B 327
 None
 0.79A 4rtbA-4pswA:
undetectable		 4rtbA-4pswA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 12 ASP B 213
THR B 143
THR B 136
ALA B 135
ALA B 124
 None
 1.41A 4u15A-4pswB:
undetectable		 4u15A-4pswB:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 12 ASP B 213
THR B 143
THR B 136
ALA B 135
ALA B 124
 None
 1.42A 4u15B-4pswB:
undetectable		 4u15B-4pswB:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 11 VAL A  24
ILE A  23
TYR A 226
ILE A 188
PHE A  63
 None
 1.18A 5d75A-4pswA:
undetectable		 5d75A-4pswA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.45A 5eeuN-4pswB:
undetectable
5eeuO-4pswB:
undetectable		 5eeuN-4pswB:
12.07
5eeuO-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.45A 5eevN-4pswB:
undetectable
5eevO-4pswB:
undetectable		 5eevN-4pswB:
12.07
5eevO-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.45A 5eewN-4pswB:
undetectable
5eewO-4pswB:
undetectable		 5eewN-4pswB:
12.07
5eewO-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.45A 5eexN-4pswB:
undetectable
5eexO-4pswB:
undetectable		 5eexN-4pswB:
12.07
5eexO-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.45A 5eeyN-4pswB:
undetectable
5eeyO-4pswB:
undetectable		 5eeyN-4pswB:
12.07
5eeyO-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.44A 5eezN-4pswB:
undetectable
5eezO-4pswB:
undetectable		 5eezN-4pswB:
12.07
5eezO-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.45A 5ef0N-4pswB:
undetectable
5ef0O-4pswB:
undetectable		 5ef0N-4pswB:
12.07
5ef0O-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.45A 5ef1N-4pswB:
undetectable
5ef1O-4pswB:
undetectable		 5ef1N-4pswB:
12.07
5ef1O-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.45A 5ef2N-4pswB:
undetectable
5ef2O-4pswB:
undetectable		 5ef2N-4pswB:
12.07
5ef2O-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 GLY B  62
HIS B 117
THR B  65
HIS B  64
THR B  63
 None
 1.44A 5ef3N-4pswB:
undetectable
5ef3O-4pswB:
undetectable		 5ef3N-4pswB:
12.07
5ef3O-4pswB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
HISTONE H4 TYPE VIII
(Ophiophagus
hannah;
Saccharomyces
cerevisiae) 		5 / 12 TYR A 194
GLY C  11
LEU B 278
PHE B 303
GLY B 309
 None
 1.23A 5fsaB-4pswA:
undetectable		 5fsaB-4pswA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 ILE B 211
MET B 272
ASP B 230
 None
 0.84A 5h2uA-4pswB:
undetectable		 5h2uA-4pswB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 6 ASP B 161
ASP B 213
ARG B 123
ASN B 162
 None
 1.26A 5l6eA-4pswB:
undetectable		 5l6eA-4pswB:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 6 LEU B  23
ILE B 345
MET B 322
TRP B 366
 None
 1.26A 5ljeA-4pswB:
undetectable		 5ljeA-4pswB:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 6 GLY B 179
SER B 228
THR B 226
VAL B 185
 None
 1.17A 5ysiA-4pswB:
undetectable		 5ysiA-4pswB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 10 SER B  37
GLY B  62
ILE B 109
ALA B  76
LEU B  59
 None
 1.38A 5zjiA-4pswB:
undetectable
5zjiJ-4pswB:
undetectable		 5zjiA-4pswB:
12.63
5zjiJ-4pswB:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 8 TYR A  71
VAL A  83
VAL A  98
VAL A  67
 None
 0.80A 6cp4A-4pswA:
undetectable		 6cp4A-4pswA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 4psw HISTONE
ACETYLTRANSFERASE
TYPE B SUBUNIT 2
HISTONE H4 TYPE VIII
(Saccharomyces
cerevisiae;
Ophiophagus
hannah) 		3 / 3 ARG C  41
ARG C  42
ASP B 339
 None
 0.86A 6d8pA-4pswC:
undetectable		 6d8pA-4pswC:
5.42