SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4puf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.15A 1dz4A-4pufA:
undetectable		 1dz4A-4pufA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.14A 1dz4B-4pufA:
undetectable		 1dz4B-4pufA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		5 / 11 ILE A 369
LEU A 319
PRO A 345
LEU A 327
ASN A 356
 None
 1.50A 1mrlA-4pufA:
undetectable
1mrlB-4pufA:
undetectable		 1mrlA-4pufA:
15.34
1mrlB-4pufA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 5 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.16A 1t88B-4pufA:
undetectable		 1t88B-4pufA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		3 / 3 GLY A 189
GLU A 210
ASN A 164
 None
 0.48A 1zq9A-4pufA:
undetectable		 1zq9A-4pufA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		5 / 12 LEU A 340
LEU A 319
GLY A 333
ASP A 352
ASN A 335
 None
 1.31A 2bm9B-4pufA:
undetectable		 2bm9B-4pufA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		5 / 12 LEU A 588
LEU A 624
GLY A 613
ASP A 606
ASN A 616
 None
 1.12A 2bm9B-4pufA:
undetectable		 2bm9B-4pufA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 5 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.19A 2m56A-4pufA:
undetectable		 2m56A-4pufA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 8 THR A 506
ASP A 606
TRP A 472
TYR A 554
 None
 1.07A 2xz5A-4pufA:
undetectable
2xz5C-4pufA:
undetectable		 2xz5A-4pufA:
16.21
2xz5C-4pufA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.11A 3fwgA-4pufA:
undetectable		 3fwgA-4pufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 VAL A 518
VAL A 469
TRP A 472
PHE A 496
 None
 1.47A 3jx4A-4pufA:
undetectable
3jx4B-4pufA:
0.9		 3jx4A-4pufA:
21.54
3jx4B-4pufA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 VAL A 518
VAL A 469
TRP A 472
PHE A 496
 None
 1.40A 3n61A-4pufA:
undetectable
3n61B-4pufA:
undetectable		 3n61A-4pufA:
21.54
3n61B-4pufA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 THR A 181
ASN A 179
CYH A 175
ILE A 197
 None
 1.41A 3w9tB-4pufA:
undetectable		 3w9tB-4pufA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.12A 3wrhE-4pufA:
undetectable		 3wrhE-4pufA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.13A 3wrjE-4pufA:
undetectable		 3wrjE-4pufA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 5 GLN A 219
ILE A 197
TYR A 196
GLU A 152
 None
 1.20A 4a99D-4pufA:
undetectable		 4a99D-4pufA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 LEU A 206
LEU A 204
ILE A 201
MET A 172
 None
 0.98A 4do3B-4pufA:
undetectable		 4do3B-4pufA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.14A 4g3rB-4pufA:
undetectable		 4g3rB-4pufA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 7 ILE A 538
THR A 534
VAL A 550
ASP A 501
 None
 1.14A 4iarA-4pufA:
undetectable		 4iarA-4pufA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 5 PHE A 663
LEU A 673
VAL A 672
VAL A 756
 None
 1.14A 4l49A-4pufA:
undetectable		 4l49A-4pufA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 8 PHE A 663
LEU A 673
VAL A 756
ILE A 579
 None
 0.83A 4l4cB-4pufA:
undetectable		 4l4cB-4pufA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 7 PRO A 383
GLU A 363
ASP A 505
THR A 509
 None
 1.31A 4uacA-4pufA:
undetectable		 4uacA-4pufA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 VAL A 518
VAL A 469
TRP A 472
PHE A 496
 None
 1.41A 5addA-4pufA:
undetectable
5addB-4pufA:
undetectable		 5addA-4pufA:
21.54
5addB-4pufA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		5 / 12 ILE A 369
LEU A 327
VAL A 353
LEU A 390
THR A 329
 None
 1.27A 5bykA-4pufA:
undetectable		 5bykA-4pufA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 8 THR A 202
LEU A 204
ILE A 197
PRO A 240
 None
 0.80A 5g48A-4pufA:
undetectable		 5g48A-4pufA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 8 ILE A 243
PRO A 240
ILE A 193
LEU A 267
 None
 0.83A 5ieoA-4pufA:
undetectable		 5ieoA-4pufA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 8 ILE A 243
PRO A 240
MET A 172
ILE A 193
 None
 0.99A 5ieoA-4pufA:
undetectable		 5ieoA-4pufA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4puf E3 UBIQUITIN-PROTEIN
LIGASE SLRP
(Salmonella
enterica) 		4 / 6 VAL A 550
VAL A 599
ILE A 639
PHE A 614
 None
 1.07A 5jw1B-4pufA:
undetectable		 5jw1B-4pufA:
21.93