SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pug'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 4pug BOLA LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 10 LEU A  85
ILE A  87
LEU A 143
LEU A 135
VAL A 131
 None
 1.11A 1cqpA-4pugA:
undetectable
1cqpB-4pugA:
undetectable		 1cqpA-4pugA:
17.54
1cqpB-4pugA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 4pug BOLA LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 8 LEU A  85
PRO A 153
SER A 156
GLY A 118
 None
 1.11A 2qd5B-4pugA:
undetectable		 2qd5B-4pugA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4pug BOLA LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 LEU A  85
PRO A 153
SER A 156
GLY A 118
 None
 1.07A 3hcnA-4pugA:
undetectable		 3hcnA-4pugA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4pug BOLA LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 8 LEU A  85
PRO A 153
SER A 156
GLY A 118
 None
 1.13A 3hcrA-4pugA:
undetectable		 3hcrA-4pugA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4pug BOLA LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 8 GLU A 107
SER A  91
GLY A  96
PHE A 110
 None
 0.85A 5flcB-4pugA:
undetectable		 5flcB-4pugA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 4pug BOLA LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 8 GLU A 107
SER A  91
GLY A  96
PHE A 110
 None
 0.85A 5flcF-4pugA:
undetectable		 5flcF-4pugA:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4pug BOLA LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 10 ARG A  73
ALA A  69
LEU A  76
LEU A  85
LEU A 135
 None
 1.02A 6f6nA-4pugA:
undetectable
6f6nB-4pugA:
undetectable		 6f6nA-4pugA:
21.15
6f6nB-4pugA:
20.83