SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pv1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 4pv1 CYTOCHROME B6-F
COMPLEX SUBUNIT 7
CYTOCHROME B6-F
COMPLEX SUBUNIT 8
(Mastigocladus
laminosus;
Mastigocladus
laminosus) 		3 / 3 TRP F  20
ALA H  20
VAL F  24
 None
 0.97A 1bdwA-4pv1F:
undetectable
1bdwB-4pv1F:
undetectable		 1bdwA-4pv1F:
24.14
1bdwB-4pv1F:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 4pv1 CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Mastigocladus
laminosus) 		5 / 11 ILE D  91
ILE D 160
GLY D  76
LEU D  70
PHE D  69
 None
 1.16A 2azyA-4pv1D:
undetectable		 2azyA-4pv1D:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4pv1 CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Mastigocladus
laminosus) 		4 / 4 ALA D 144
HIS D 110
HIS D 129
PRO D 143
 None
FES  D 201 (-3.0A)
FES  D 201 (-2.7A)
None
 1.32A 3mbgC-4pv1D:
undetectable		 3mbgC-4pv1D:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 4pv1 CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Mastigocladus
laminosus) 		3 / 3 ARG D 100
PHE D 124
ARG D  78
 None
 1.19A 5y9yA-4pv1D:
undetectable		 5y9yA-4pv1D:
19.42