SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pv6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7H_B_SAMB530_1 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	4pv6	N-TERMINAL ACETYLTRANSFERASE COMPLEX SUBUNIT [ARD1] (Thermoplasma volcanium)	3 / 3	TYR C 70 GLU C 114 THR C 134	None	0.83A	2y7hB-4pv6C: undetectable	2y7hB-4pv6C: 14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DFB_B_KANB401_1 (APH(2')-ID)	4pv6	N-TERMINAL ACETYLTRANSFERASE COMPLEX SUBUNIT [ARD1] (Thermoplasma volcanium)	5 / 10	ASP C 118 SER C 145 ASP C 143 GLU C 34 GLU C 114	None	1.45A	4dfbB-4pv6C: 0.0	4dfbB-4pv6C: 18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E1G_A_LNLA701_2 (PROSTAGLANDIN G/H SYNTHASE 2)	4pv6	N-TERMINAL ACETYLTRANSFERASE COMPLEX SUBUNIT [ARD1] (Thermoplasma volcanium)	4 / 5	ARG C 152 LEU C 102 SER C 101 MET C 108	None	1.28A	4e1gA-4pv6C: undetectable	4e1gA-4pv6C: 12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_E_ACTE403_0 (PROTON-GATED ION CHANNEL)	4pv6	N-TERMINAL ACETYLTRANSFERASE COMPLEX SUBUNIT [ARD1] (Thermoplasma volcanium)	3 / 3	ARG C 76 TYR C 140 GLU C 114	None	0.65A	4zzbE-4pv6C: undetectable	4zzbE-4pv6C: 19.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y7H_B_SAMB530_1","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","4pv6","N-TERMINAL ACETYLTRANSFERASE COMPLEX SUBUNIT [ARD1]","Thermoplasma volcanium",3,"TYR C  70;GLU C 114;THR C 134","None","0.83A","2y7hB-4pv6C:undetectable","2y7hB-4pv6C:14.31"],["4DFB_B_KANB401_1","APH(2')-ID","4pv6","N-TERMINAL ACETYLTRANSFERASE COMPLEX SUBUNIT [ARD1]","Thermoplasma volcanium",5,"ASP C 118;SER C 145;ASP C 143;GLU C  34;GLU C 114","None","1.45A","4dfbB-4pv6C:0.0","4dfbB-4pv6C:18.40"],["4E1G_A_LNLA701_2","PROSTAGLANDIN G\/H SYNTHASE 2","4pv6","N-TERMINAL ACETYLTRANSFERASE COMPLEX SUBUNIT [ARD1]","Thermoplasma volcanium",4,"ARG C 152;LEU C 102;SER C 101;MET C 108","None","1.28A","4e1gA-4pv6C:undetectable","4e1gA-4pv6C:12.97"],["4ZZB_E_ACTE403_0","PROTON-GATED ION CHANNEL","4pv6","N-TERMINAL ACETYLTRANSFERASE COMPLEX SUBUNIT [ARD1]","Thermoplasma volcanium",3,"ARG C  76;TYR C 140;GLU C 114","None","0.65A","4zzbE-4pv6C:undetectable","4zzbE-4pv6C:19.18"]]