SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4pxn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ALX_B_DVAB6_0
(GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 TRP A 188
TRP A 174
ALA A 176
VAL A 171
 None
 1.21A 1alxA-4pxnA:
undetectable
1alxB-4pxnA:
undetectable		 1alxA-4pxnA:
2.80
1alxB-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 LEU A 307
ALA A 292
ILE A 455
VAL A 276
ILE A 274
 None
 0.95A 1hxbB-4pxnA:
undetectable		 1hxbB-4pxnA:
11.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 10 PHE A 243
THR A 244
THR A 194
ILE A 197
THR A 198
 NAD  A 601 (-4.3A)
NAD  A 601 (-4.1A)
None
None
None
 1.09A 1i18A-4pxnA:
undetectable
1i18B-4pxnA:
undetectable		 1i18A-4pxnA:
12.68
1i18B-4pxnA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		3 / 3 ALA A 176
VAL A 181
TRP A  73
 None
 0.88A 1nt5A-4pxnA:
undetectable		 1nt5A-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		3 / 3 ALA A 176
VAL A 181
TRP A  73
 None
 0.88A 1nt5B-4pxnA:
undetectable		 1nt5B-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA6_0
(GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.45A 2xdcA-4pxnA:
undetectable
2xdcB-4pxnA:
undetectable		 2xdcA-4pxnA:
2.60
2xdcB-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB6_0
(GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 TRP A 188
TRP A 174
ALA A 176
VAL A 171
 None
 1.43A 2xdcA-4pxnA:
undetectable
2xdcB-4pxnA:
undetectable		 2xdcA-4pxnA:
2.60
2xdcB-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC6_0
(GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.32A 2xdcC-4pxnA:
undetectable
2xdcD-4pxnA:
undetectable		 2xdcC-4pxnA:
2.60
2xdcD-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_E_DVAE6_0
(GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.35A 2xdcE-4pxnA:
undetectable
2xdcF-4pxnA:
undetectable		 2xdcE-4pxnA:
2.60
2xdcF-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.43A 2y5mA-4pxnA:
undetectable
2y5mB-4pxnA:
undetectable		 2y5mA-4pxnA:
2.60
2y5mB-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_B_DVAB6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 TRP A 188
TRP A 174
ALA A 176
VAL A 171
 None
 1.44A 2y5mA-4pxnA:
undetectable
2y5mB-4pxnA:
undetectable		 2y5mA-4pxnA:
2.60
2y5mB-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_C_DVAC6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.33A 2y5mC-4pxnA:
undetectable
2y5mD-4pxnA:
undetectable		 2y5mC-4pxnA:
2.60
2y5mD-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_E_DVAE6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.33A 2y5mE-4pxnA:
undetectable
2y5mF-4pxnA:
undetectable		 2y5mE-4pxnA:
2.60
2y5mF-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.44A 2y6nA-4pxnA:
undetectable
2y6nB-4pxnA:
undetectable		 2y6nA-4pxnA:
2.60
2y6nB-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 TRP A 188
TRP A 174
ALA A 176
VAL A 171
 None
 1.45A 2y6nA-4pxnA:
undetectable
2y6nB-4pxnA:
undetectable		 2y6nA-4pxnA:
2.60
2y6nB-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_C_DVAC6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.33A 2y6nC-4pxnA:
undetectable
2y6nD-4pxnA:
undetectable		 2y6nC-4pxnA:
2.60
2y6nD-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_E_DVAE6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 ALA A 176
VAL A 171
TRP A 188
TRP A 174
 None
 1.33A 2y6nE-4pxnA:
undetectable
2y6nF-4pxnA:
undetectable		 2y6nE-4pxnA:
2.60
2y6nF-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		3 / 3 LEU A 131
TRP A 174
TYR A 486
 None
 1.00A 3aicB-4pxnA:
undetectable		 3aicB-4pxnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		3 / 3 LEU A 131
TRP A 174
TYR A 486
 None
 0.99A 3aicE-4pxnA:
undetectable		 3aicE-4pxnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		3 / 3 LEU A 131
TRP A 174
TYR A 486
 None
 0.98A 3aicG-4pxnA:
undetectable		 3aicG-4pxnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		3 / 3 LEU A 131
TRP A 174
TYR A 486
 None
 1.00A 3aicH-4pxnA:
undetectable		 3aicH-4pxnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 VAL A 393
VAL A 394
GLN A 423
PHE A 352
 None
 1.27A 3bjwH-4pxnA:
undetectable		 3bjwH-4pxnA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 LEU A 307
ALA A 292
ILE A 455
VAL A 276
ILE A 274
 None
 1.03A 3cyxA-4pxnA:
undetectable		 3cyxA-4pxnA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 ASN A 454
ILE A 436
THR A 431
ASP A 279
ILE A 275
 None
 1.23A 3kpbA-4pxnA:
undetectable		 3kpbA-4pxnA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 LEU A 307
ALA A 292
ILE A 455
VAL A 276
ILE A 274
 None
 1.04A 3mwsB-4pxnA:
undetectable		 3mwsB-4pxnA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 11 LEU A 307
ALA A 292
ILE A 455
VAL A 276
ILE A 274
 None
 1.03A 3oxxB-4pxnA:
undetectable		 3oxxB-4pxnA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_2
(HIV-1 PROTEASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 11 LEU A 307
ALA A 292
ILE A 455
VAL A 276
ILE A 274
 None
 0.97A 3oxxD-4pxnA:
undetectable		 3oxxD-4pxnA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 TRP A 188
TRP A 174
ALA A 176
VAL A 171
 None
 1.37A 3zq8A-4pxnA:
undetectable
3zq8B-4pxnA:
undetectable		 3zq8A-4pxnA:
2.60
3zq8B-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD6_0
(VAL-GRAMICIDIN A)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 TRP A 188
TRP A 174
ALA A 176
VAL A 171
 None
 1.47A 3zq8C-4pxnA:
undetectable
3zq8D-4pxnA:
undetectable		 3zq8C-4pxnA:
2.60
3zq8D-4pxnA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 LEU A 214
PRO A 215
LEU A 209
ILE A  84
 None
 0.98A 4f4dB-4pxnA:
2.7		 4f4dB-4pxnA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 GLU A 477
GLY A 467
VAL A 159
TYR A 486
ASN A 175
 NAD  A 601 ( 4.8A)
None
None
None
None
 1.11A 4ffwA-4pxnA:
undetectable		 4ffwA-4pxnA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 10 GLY A 475
GLY A 474
GLU A 477
ASN A 175
VAL A 161
 None
None
NAD  A 601 ( 4.8A)
None
None
 1.25A 4fgkA-4pxnA:
0.8
4fgkB-4pxnA:
1.4		 4fgkA-4pxnA:
18.22
4fgkB-4pxnA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 6 ALA A 176
ASN A 175
LEU A 172
VAL A 171
 None
 0.90A 4g24A-4pxnA:
undetectable		 4g24A-4pxnA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 LEU A 340
PHE A 167
LEU A 398
PHE A 399
THR A 303
 None
None
None
NAD  A 601 (-3.9A)
None
 1.22A 4iaqA-4pxnA:
undetectable		 4iaqA-4pxnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 LEU A 214
PRO A 215
LEU A 209
ILE A  84
 None
 0.80A 4klrA-4pxnA:
2.5		 4klrA-4pxnA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		3 / 3 GLY A 341
PRO A 342
GLN A 299
 None
 0.43A 4oltB-4pxnA:
undetectable		 4oltB-4pxnA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 ALA A 170
VAL A 171
CYH A 169
ALA A 164
LEU A 268
 None
None
None
NAD  A 601 (-3.3A)
None
 1.17A 4qrcA-4pxnA:
undetectable		 4qrcA-4pxnA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		3 / 3 GLY A 341
PRO A 342
GLN A 299
 None
 0.33A 4qwpB-4pxnA:
undetectable		 4qwpB-4pxnA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 6 LEU A 172
TRP A 188
SER A 221
GLU A  53
 None
 1.29A 5b8iA-4pxnA:
undetectable		 5b8iA-4pxnA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 6 SER A 428
GLY A 468
THR A 244
GLU A 267
 None
None
NAD  A 601 (-4.1A)
NAD  A 601 (-4.3A)
 1.07A 5btcA-4pxnA:
undetectable
5btcC-4pxnA:
undetectable
5btcD-4pxnA:
undetectable		 5btcA-4pxnA:
22.43
5btcC-4pxnA:
22.43
5btcD-4pxnA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 6 SER A 428
GLY A 468
THR A 244
GLU A 267
 None
None
NAD  A 601 (-4.1A)
NAD  A 601 (-4.3A)
 1.09A 5btcA-4pxnA:
undetectable
5btcB-4pxnA:
undetectable
5btcC-4pxnA:
undetectable		 5btcA-4pxnA:
22.43
5btcB-4pxnA:
19.66
5btcC-4pxnA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 SER A 428
GLY A 468
THR A 244
GLU A 267
 None
None
NAD  A 601 (-4.1A)
NAD  A 601 (-4.3A)
 1.11A 5btiA-4pxnA:
undetectable
5btiB-4pxnA:
undetectable		 5btiA-4pxnA:
22.43
5btiB-4pxnA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 SER A 428
GLY A 468
THR A 244
GLU A 267
 None
None
NAD  A 601 (-4.1A)
NAD  A 601 (-4.3A)
 1.09A 5btiC-4pxnA:
undetectable
5btiD-4pxnA:
undetectable		 5btiC-4pxnA:
22.43
5btiD-4pxnA:
19.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 9 ILE A  88
LEU A 180
TRP A  73
ASN A 212
LEU A 214
 None
 1.40A 5fhzB-4pxnA:
48.5		 5fhzB-4pxnA:
32.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 GLY A 270
GLN A 423
LEU A 343
PHE A 352
GLY A 370
 None
 1.25A 5fsaB-4pxnA:
undetectable		 5fsaB-4pxnA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 4 VAL A 118
GLU A 117
GLY A 100
LEU A  99
 None
 0.89A 5g5gC-4pxnA:
undetectable		 5g5gC-4pxnA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 ILE A 197
GLU A 267
ALA A 179
ALA A 176
GLY A 160
 None
NAD  A 601 (-4.3A)
None
None
None
 1.29A 5igpA-4pxnA:
undetectable		 5igpA-4pxnA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_J_EDTJ301_0
(TCRBETA CHAIN)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 TYR A 486
GLU A 267
GLY A 475
SER A 482
 None
NAD  A 601 (-4.3A)
None
None
 1.19A 5jhdJ-4pxnA:
undetectable		 5jhdJ-4pxnA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 LEU A 307
ALA A 292
ILE A 455
VAL A 276
ILE A 274
 None
 0.99A 5kqyA-4pxnA:
undetectable		 5kqyA-4pxnA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 8 GLY A 468
LYS A 470
ALA A 471
ASP A 447
 None
 0.91A 5mvsB-4pxnA:
5.6		 5mvsB-4pxnA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 8 GLU A 113
GLY A 341
LEU A 340
THR A 338
 None
 1.07A 5sxqB-4pxnA:
undetectable		 5sxqB-4pxnA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 8 GLU A 113
GLY A 341
LEU A 340
THR A 338
 None
 1.08A 5syjA-4pxnA:
undetectable		 5syjA-4pxnA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 PHE A 399
ALA A 191
THR A 194
ILE A 197
GLU A 120
 NAD  A 601 (-3.9A)
NAD  A 601 (-4.2A)
None
None
None
 1.07A 5vceA-4pxnA:
undetectable		 5vceA-4pxnA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 LEU A  15
LEU A  92
THR A 198
ARG A 300
 None
 1.10A 6ew0F-4pxnA:
undetectable		 6ew0F-4pxnA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 VAL A 421
LYS A 395
ASN A 271
PRO A 389
 None
 1.37A 6fi4A-4pxnA:
undetectable
6fi4B-4pxnA:
undetectable		 6fi4A-4pxnA:
17.47
6fi4B-4pxnA:
80.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		5 / 12 PRO A 434
ILE A 437
ILE A 436
VAL A 453
ILE A 429
 None
 1.04A 6hlpA-4pxnA:
3.8		 6hlpA-4pxnA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 4pxn UNCHARACTERIZED
PROTEIN
(Zea
mays) 		4 / 5 GLY A 475
SER A 482
TYR A 486
GLN A 485
 None
 0.95A 6ji6A-4pxnA:
undetectable		 6ji6A-4pxnA:
17.92