SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q00'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		5 / 12 ALA A 118
ILE A 116
PHE A  45
LEU A  54
LEU A   8
 None
 1.11A 1dtlA-4q00A:
undetectable		 1dtlA-4q00A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		4 / 8 ILE A 252
ASN A  11
ASN A 101
LEU A 141
 None
 0.89A 1dzmA-4q00A:
undetectable		 1dzmA-4q00A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		4 / 5 SER A 215
LEU A 206
GLY A 205
ARG A 248
 None
 0.93A 2j2pA-4q00A:
undetectable
2j2pB-4q00A:
undetectable		 2j2pA-4q00A:
18.82
2j2pB-4q00A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		4 / 6 ARG A 248
SER A 215
LEU A 206
GLY A 205
 None
 0.85A 2j2pA-4q00A:
undetectable
2j2pC-4q00A:
undetectable		 2j2pA-4q00A:
18.82
2j2pC-4q00A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		4 / 6 ARG A 248
SER A 215
LEU A 206
GLY A 205
 None
 0.87A 2j2pD-4q00A:
undetectable
2j2pF-4q00A:
undetectable		 2j2pD-4q00A:
18.82
2j2pF-4q00A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		4 / 7 ILE A 113
GLY A  84
TYR A 218
LEU A  57
 None
 0.85A 3elzA-4q00A:
undetectable		 3elzA-4q00A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 111
GLY A  84
ASP A  87
GLY A   7
ILE A 113
 None
 0.94A 3k4vD-4q00A:
undetectable		 3k4vD-4q00A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 111
GLY A  84
ASP A  87
GLY A   7
ILE A 113
 None
 0.95A 3ndtD-4q00A:
undetectable		 3ndtD-4q00A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 111
GLY A  84
ASP A  87
GLY A   7
ILE A 113
 None
 0.95A 3nduD-4q00A:
undetectable		 3nduD-4q00A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A 111
GLY A  84
ASP A  87
GLY A   7
ILE A 113
 None
 1.00A 3oxxA-4q00A:
undetectable		 3oxxA-4q00A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		3 / 3 ARG A 140
TYR A 103
ASN A  91
 None
 0.86A 4ffwB-4q00A:
3.0		 4ffwB-4q00A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		4 / 7 LEU A 102
ASN A  91
GLN A 107
LEU A 108
 None
 1.09A 4ib4A-4q00A:
undetectable		 4ib4A-4q00A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		4 / 6 LEU A 102
ASN A  91
GLN A 107
LEU A 108
 None
 1.10A 4nc3A-4q00A:
undetectable		 4nc3A-4q00A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		5 / 9 ASP A  56
LEU A   8
GLY A   7
LEU A  89
LEU A 108
 None
 1.23A 5dqfA-4q00A:
undetectable		 5dqfA-4q00A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4q00 FERROUS IRON
TRANSPORT PROTEIN B
(Escherichia
coli) 		5 / 11 ILE A   6
ILE A  90
VAL A  52
GLU A 157
ALA A 162
 None
 1.06A 5lg3A-4q00A:
undetectable		 5lg3A-4q00A:
22.42