SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.39A 1c9sA-4q0gA:
undetectable
1c9sK-4q0gA:
undetectable		 1c9sA-4q0gA:
9.33
1c9sK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.36A 1c9sA-4q0gA:
undetectable
1c9sB-4q0gA:
undetectable		 1c9sA-4q0gA:
9.33
1c9sB-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 1c9sB-4q0gA:
undetectable
1c9sC-4q0gA:
undetectable		 1c9sB-4q0gA:
9.33
1c9sC-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 1c9sC-4q0gA:
undetectable
1c9sD-4q0gA:
undetectable		 1c9sC-4q0gA:
9.33
1c9sD-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 1c9sD-4q0gA:
undetectable
1c9sE-4q0gA:
undetectable		 1c9sD-4q0gA:
9.33
1c9sE-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 1c9sE-4q0gA:
undetectable
1c9sF-4q0gA:
undetectable		 1c9sE-4q0gA:
9.33
1c9sF-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 1c9sF-4q0gA:
undetectable
1c9sG-4q0gA:
undetectable		 1c9sF-4q0gA:
9.33
1c9sG-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 1c9sG-4q0gA:
undetectable
1c9sH-4q0gA:
undetectable		 1c9sG-4q0gA:
9.33
1c9sH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.36A 1c9sH-4q0gA:
undetectable
1c9sI-4q0gA:
undetectable		 1c9sH-4q0gA:
9.33
1c9sI-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 1c9sJ-4q0gA:
undetectable
1c9sK-4q0gA:
undetectable		 1c9sJ-4q0gA:
9.33
1c9sK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 1c9sL-4q0gA:
undetectable
1c9sM-4q0gA:
undetectable		 1c9sL-4q0gA:
9.33
1c9sM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 1c9sM-4q0gA:
undetectable
1c9sN-4q0gA:
undetectable		 1c9sM-4q0gA:
9.33
1c9sN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.32A 1c9sO-4q0gA:
undetectable
1c9sP-4q0gA:
undetectable		 1c9sO-4q0gA:
9.33
1c9sP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 1c9sR-4q0gA:
undetectable
1c9sS-4q0gA:
undetectable		 1c9sR-4q0gA:
9.33
1c9sS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 1c9sS-4q0gA:
undetectable
1c9sT-4q0gA:
undetectable		 1c9sS-4q0gA:
9.33
1c9sT-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 7 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 1c9sT-4q0gA:
undetectable
1c9sU-4q0gA:
undetectable		 1c9sT-4q0gA:
9.33
1c9sU-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.40A 1gtfA-4q0gA:
undetectable
1gtfK-4q0gA:
undetectable		 1gtfA-4q0gA:
9.33
1gtfK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 1gtfA-4q0gA:
undetectable
1gtfB-4q0gA:
undetectable		 1gtfA-4q0gA:
9.33
1gtfB-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 1gtfB-4q0gA:
undetectable
1gtfC-4q0gA:
undetectable		 1gtfB-4q0gA:
9.33
1gtfC-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.41A 1gtfC-4q0gA:
undetectable
1gtfD-4q0gA:
undetectable		 1gtfC-4q0gA:
9.33
1gtfD-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 1gtfE-4q0gA:
undetectable
1gtfF-4q0gA:
undetectable		 1gtfE-4q0gA:
9.33
1gtfF-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 1gtfF-4q0gA:
undetectable
1gtfG-4q0gA:
undetectable		 1gtfF-4q0gA:
9.33
1gtfG-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 1gtfG-4q0gA:
undetectable
1gtfH-4q0gA:
undetectable		 1gtfG-4q0gA:
9.33
1gtfH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.41A 1gtfH-4q0gA:
undetectable
1gtfI-4q0gA:
undetectable		 1gtfH-4q0gA:
9.33
1gtfI-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 1gtfI-4q0gA:
undetectable
1gtfJ-4q0gA:
undetectable		 1gtfI-4q0gA:
9.33
1gtfJ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 7 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 1gtfL-4q0gA:
undetectable
1gtfM-4q0gA:
undetectable		 1gtfL-4q0gA:
9.33
1gtfM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 1gtfM-4q0gA:
undetectable
1gtfN-4q0gA:
undetectable		 1gtfM-4q0gA:
9.33
1gtfN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 8 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 1gtfN-4q0gA:
undetectable
1gtfO-4q0gA:
undetectable		 1gtfN-4q0gA:
9.33
1gtfO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 1gtfO-4q0gA:
undetectable
1gtfP-4q0gA:
undetectable		 1gtfO-4q0gA:
9.33
1gtfP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 1gtfP-4q0gA:
undetectable
1gtfQ-4q0gA:
undetectable		 1gtfP-4q0gA:
9.33
1gtfQ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 1gtfT-4q0gA:
undetectable
1gtfU-4q0gA:
undetectable		 1gtfT-4q0gA:
9.33
1gtfU-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 1gtfU-4q0gA:
undetectable
1gtfV-4q0gA:
undetectable		 1gtfU-4q0gA:
9.33
1gtfV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.34A 1gtfL-4q0gA:
undetectable
1gtfV-4q0gA:
undetectable		 1gtfL-4q0gA:
9.33
1gtfV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		4 / 7 SER A 346
GLY A 372
THR A 320
ILE A 370
 None
 0.95A 1gtnF-4q0gA:
undetectable
1gtnG-4q0gA:
undetectable		 1gtnF-4q0gA:
9.33
1gtnG-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 1gtnN-4q0gA:
undetectable
1gtnO-4q0gA:
undetectable		 1gtnN-4q0gA:
9.33
1gtnO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.35A 1gtnO-4q0gA:
undetectable
1gtnP-4q0gA:
undetectable		 1gtnO-4q0gA:
9.33
1gtnP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
THR A 115
THR A  87
ALA A  68
 None
 1.32A 1gtnQ-4q0gA:
undetectable
1gtnR-4q0gA:
undetectable		 1gtnQ-4q0gA:
9.33
1gtnR-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.30A 1gtnR-4q0gA:
undetectable
1gtnS-4q0gA:
undetectable		 1gtnR-4q0gA:
9.33
1gtnS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.39A 1gtnU-4q0gA:
undetectable
1gtnV-4q0gA:
undetectable		 1gtnU-4q0gA:
9.33
1gtnV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 12 THR A  87
ALA A  68
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 1gtnL-4q0gA:
undetectable
1gtnV-4q0gA:
undetectable		 1gtnL-4q0gA:
9.33
1gtnV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 11 LEU A 342
ILE A 354
LYS A 390
VAL A 336
PHE A 366
 None
 1.42A 1gx9A-4q0gA:
1.6		 1gx9A-4q0gA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 299
VAL A 305
GLU A 312
ALA A 337
LEU A 365
 None
 1.01A 1sn5B-4q0gA:
undetectable
1sn5D-4q0gA:
undetectable		 1sn5B-4q0gA:
14.18
1sn5D-4q0gA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_D_T3D602_1
(TRANSTHYRETIN)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 312
ALA A 337
LEU A 365
GLU A 299
VAL A 305
 None
 1.03A 1sn5B-4q0gA:
undetectable
1sn5D-4q0gA:
undetectable		 1sn5B-4q0gA:
14.18
1sn5D-4q0gA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.39A 1utdA-4q0gA:
undetectable
1utdB-4q0gA:
undetectable		 1utdA-4q0gA:
9.33
1utdB-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.39A 1utdC-4q0gA:
undetectable
1utdD-4q0gA:
undetectable		 1utdC-4q0gA:
9.33
1utdD-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.38A 1utdD-4q0gA:
undetectable
1utdE-4q0gA:
undetectable		 1utdD-4q0gA:
9.33
1utdE-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.38A 1utdG-4q0gA:
undetectable
1utdH-4q0gA:
undetectable		 1utdG-4q0gA:
9.33
1utdH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 1utdA-4q0gA:
undetectable
1utdK-4q0gA:
undetectable		 1utdA-4q0gA:
9.33
1utdK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 12 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.35A 1utdL-4q0gA:
undetectable
1utdM-4q0gA:
undetectable		 1utdL-4q0gA:
9.33
1utdM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 11 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 1utdM-4q0gA:
undetectable
1utdN-4q0gA:
undetectable		 1utdM-4q0gA:
9.33
1utdN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 1utdN-4q0gA:
undetectable
1utdO-4q0gA:
undetectable		 1utdN-4q0gA:
9.33
1utdO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 12 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.37A 1utdO-4q0gA:
undetectable
1utdP-4q0gA:
undetectable		 1utdO-4q0gA:
9.33
1utdP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 11 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 1utdP-4q0gA:
undetectable
1utdQ-4q0gA:
undetectable		 1utdP-4q0gA:
9.33
1utdQ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 1utdQ-4q0gA:
undetectable
1utdR-4q0gA:
undetectable		 1utdQ-4q0gA:
9.33
1utdR-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 1utdR-4q0gA:
undetectable
1utdS-4q0gA:
undetectable		 1utdR-4q0gA:
9.33
1utdS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_T_TRPT81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.36A 1utdT-4q0gA:
undetectable
1utdU-4q0gA:
undetectable		 1utdT-4q0gA:
9.33
1utdU-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		3 / 3 GLU A  66
THR A  87
LEU A 492
 None
 0.61A 1v8bC-4q0gA:
2.4		 1v8bC-4q0gA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 296
VAL A 297
HIS A 298
PHE A 366
VAL A 322
 None
 1.42A 2g72A-4q0gA:
undetectable		 2g72A-4q0gA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 12 HIS A  42
LEU A  49
GLY A  33
GLY A  34
ALA A 104
 None
 1.18A 3i5uA-4q0gA:
undetectable		 3i5uA-4q0gA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 12 HIS A  42
LEU A  49
GLY A  33
GLY A  34
ALA A 104
 None
 1.19A 3i5uB-4q0gA:
undetectable		 3i5uB-4q0gA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		4 / 8 THR A 323
GLY A 334
LEU A 364
ILE A 354
 None
 0.86A 3nbqB-4q0gA:
undetectable		 3nbqB-4q0gA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		4 / 8 THR A 323
GLY A 334
LEU A 364
ILE A 354
 None
 0.88A 3nbqC-4q0gA:
undetectable		 3nbqC-4q0gA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_ACTA1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 ALA A  83
ILE A  85
GLY A 109
VAL A 106
SER A  80
 None
 1.29A 4a3uA-4q0gA:
2.6		 4a3uA-4q0gA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A 503
ILE A 497
LEU A 367
GLN A 368
LEU A 428
 None
 1.33A 4r3aB-4q0gA:
undetectable		 4r3aB-4q0gA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 PHE A 161
VAL A 116
GLY A 186
PHE A 157
GLY A 158
 None
 1.17A 4xpbA-4q0gA:
2.5		 4xpbA-4q0gA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 5eeuA-4q0gA:
undetectable
5eeuB-4q0gA:
undetectable		 5eeuA-4q0gA:
9.33
5eeuB-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5eeuB-4q0gA:
undetectable
5eeuC-4q0gA:
undetectable		 5eeuB-4q0gA:
9.33
5eeuC-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eeuD-4q0gA:
undetectable
5eeuE-4q0gA:
undetectable		 5eeuD-4q0gA:
9.33
5eeuE-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.41A 5eeuE-4q0gA:
undetectable
5eeuF-4q0gA:
undetectable		 5eeuE-4q0gA:
9.33
5eeuF-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5eeuG-4q0gA:
undetectable
5eeuH-4q0gA:
undetectable		 5eeuG-4q0gA:
9.33
5eeuH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eeuH-4q0gA:
undetectable
5eeuI-4q0gA:
undetectable		 5eeuH-4q0gA:
9.33
5eeuI-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eeuJ-4q0gA:
undetectable
5eeuK-4q0gA:
undetectable		 5eeuJ-4q0gA:
9.33
5eeuK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5eeuL-4q0gA:
undetectable
5eeuV-4q0gA:
undetectable		 5eeuL-4q0gA:
9.33
5eeuV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eeuL-4q0gA:
undetectable
5eeuM-4q0gA:
undetectable		 5eeuL-4q0gA:
9.33
5eeuM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eeuM-4q0gA:
undetectable
5eeuN-4q0gA:
undetectable		 5eeuM-4q0gA:
9.33
5eeuN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eeuN-4q0gA:
undetectable
5eeuO-4q0gA:
undetectable		 5eeuN-4q0gA:
9.33
5eeuO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5eeuO-4q0gA:
undetectable
5eeuP-4q0gA:
undetectable		 5eeuO-4q0gA:
9.33
5eeuP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5eeuP-4q0gA:
undetectable
5eeuQ-4q0gA:
undetectable		 5eeuP-4q0gA:
9.33
5eeuQ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5eeuR-4q0gA:
undetectable
5eeuS-4q0gA:
undetectable		 5eeuR-4q0gA:
9.33
5eeuS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5eeuS-4q0gA:
undetectable
5eeuT-4q0gA:
undetectable		 5eeuS-4q0gA:
9.33
5eeuT-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eeuU-4q0gA:
undetectable
5eeuV-4q0gA:
undetectable		 5eeuU-4q0gA:
9.33
5eeuV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5eevB-4q0gA:
undetectable
5eevC-4q0gA:
undetectable		 5eevB-4q0gA:
9.33
5eevC-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eevD-4q0gA:
undetectable
5eevE-4q0gA:
undetectable		 5eevD-4q0gA:
9.33
5eevE-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.41A 5eevE-4q0gA:
undetectable
5eevF-4q0gA:
undetectable		 5eevE-4q0gA:
9.33
5eevF-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5eevG-4q0gA:
undetectable
5eevH-4q0gA:
undetectable		 5eevG-4q0gA:
9.33
5eevH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eevH-4q0gA:
undetectable
5eevI-4q0gA:
undetectable		 5eevH-4q0gA:
9.33
5eevI-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eevJ-4q0gA:
undetectable
5eevK-4q0gA:
undetectable		 5eevJ-4q0gA:
9.33
5eevK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eevL-4q0gA:
undetectable
5eevM-4q0gA:
undetectable		 5eevL-4q0gA:
9.33
5eevM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eevM-4q0gA:
undetectable
5eevN-4q0gA:
undetectable		 5eevM-4q0gA:
9.33
5eevN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eevN-4q0gA:
undetectable
5eevO-4q0gA:
undetectable		 5eevN-4q0gA:
9.33
5eevO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5eevO-4q0gA:
undetectable
5eevP-4q0gA:
undetectable		 5eevO-4q0gA:
9.33
5eevP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5eevP-4q0gA:
undetectable
5eevQ-4q0gA:
undetectable		 5eevP-4q0gA:
9.33
5eevQ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5eevQ-4q0gA:
undetectable
5eevR-4q0gA:
undetectable		 5eevQ-4q0gA:
9.33
5eevR-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5eevR-4q0gA:
undetectable
5eevS-4q0gA:
undetectable		 5eevR-4q0gA:
9.33
5eevS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5eevS-4q0gA:
undetectable
5eevT-4q0gA:
undetectable		 5eevS-4q0gA:
9.33
5eevT-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eevU-4q0gA:
undetectable
5eevV-4q0gA:
undetectable		 5eevU-4q0gA:
9.33
5eevV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5eewB-4q0gA:
undetectable
5eewC-4q0gA:
undetectable		 5eewB-4q0gA:
9.33
5eewC-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eewD-4q0gA:
undetectable
5eewE-4q0gA:
undetectable		 5eewD-4q0gA:
9.33
5eewE-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.41A 5eewE-4q0gA:
undetectable
5eewF-4q0gA:
undetectable		 5eewE-4q0gA:
9.33
5eewF-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5eewG-4q0gA:
undetectable
5eewH-4q0gA:
undetectable		 5eewG-4q0gA:
9.33
5eewH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eewH-4q0gA:
undetectable
5eewI-4q0gA:
undetectable		 5eewH-4q0gA:
9.33
5eewI-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eewJ-4q0gA:
undetectable
5eewK-4q0gA:
undetectable		 5eewJ-4q0gA:
9.33
5eewK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eewL-4q0gA:
undetectable
5eewM-4q0gA:
undetectable		 5eewL-4q0gA:
9.33
5eewM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eewM-4q0gA:
undetectable
5eewN-4q0gA:
undetectable		 5eewM-4q0gA:
9.33
5eewN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eewN-4q0gA:
undetectable
5eewO-4q0gA:
undetectable		 5eewN-4q0gA:
9.33
5eewO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5eewO-4q0gA:
undetectable
5eewP-4q0gA:
undetectable		 5eewO-4q0gA:
9.33
5eewP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5eewP-4q0gA:
undetectable
5eewQ-4q0gA:
undetectable		 5eewP-4q0gA:
9.33
5eewQ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5eewQ-4q0gA:
undetectable
5eewR-4q0gA:
undetectable		 5eewQ-4q0gA:
9.33
5eewR-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5eewR-4q0gA:
undetectable
5eewS-4q0gA:
undetectable		 5eewR-4q0gA:
9.33
5eewS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5eewS-4q0gA:
undetectable
5eewT-4q0gA:
undetectable		 5eewS-4q0gA:
9.33
5eewT-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eewU-4q0gA:
undetectable
5eewV-4q0gA:
undetectable		 5eewU-4q0gA:
9.33
5eewV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5eexB-4q0gA:
undetectable
5eexC-4q0gA:
undetectable		 5eexB-4q0gA:
9.33
5eexC-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eexD-4q0gA:
undetectable
5eexE-4q0gA:
undetectable		 5eexD-4q0gA:
9.33
5eexE-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.41A 5eexE-4q0gA:
undetectable
5eexF-4q0gA:
undetectable		 5eexE-4q0gA:
9.33
5eexF-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5eexG-4q0gA:
undetectable
5eexH-4q0gA:
undetectable		 5eexG-4q0gA:
9.33
5eexH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eexH-4q0gA:
undetectable
5eexI-4q0gA:
undetectable		 5eexH-4q0gA:
9.33
5eexI-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eexJ-4q0gA:
undetectable
5eexK-4q0gA:
undetectable		 5eexJ-4q0gA:
9.33
5eexK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eexL-4q0gA:
undetectable
5eexM-4q0gA:
undetectable		 5eexL-4q0gA:
9.33
5eexM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eexM-4q0gA:
undetectable
5eexN-4q0gA:
undetectable		 5eexM-4q0gA:
9.33
5eexN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eexN-4q0gA:
undetectable
5eexO-4q0gA:
undetectable		 5eexN-4q0gA:
9.33
5eexO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5eexO-4q0gA:
undetectable
5eexP-4q0gA:
undetectable		 5eexO-4q0gA:
9.33
5eexP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5eexP-4q0gA:
undetectable
5eexQ-4q0gA:
undetectable		 5eexP-4q0gA:
9.33
5eexQ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5eexQ-4q0gA:
undetectable
5eexR-4q0gA:
undetectable		 5eexQ-4q0gA:
9.33
5eexR-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5eexR-4q0gA:
undetectable
5eexS-4q0gA:
undetectable		 5eexR-4q0gA:
9.33
5eexS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5eexS-4q0gA:
undetectable
5eexT-4q0gA:
undetectable		 5eexS-4q0gA:
9.33
5eexT-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eexU-4q0gA:
undetectable
5eexV-4q0gA:
undetectable		 5eexU-4q0gA:
9.33
5eexV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5eeyB-4q0gA:
undetectable
5eeyC-4q0gA:
undetectable		 5eeyB-4q0gA:
9.33
5eeyC-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eeyD-4q0gA:
undetectable
5eeyE-4q0gA:
undetectable		 5eeyD-4q0gA:
9.33
5eeyE-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.41A 5eeyE-4q0gA:
undetectable
5eeyF-4q0gA:
undetectable		 5eeyE-4q0gA:
9.33
5eeyF-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5eeyG-4q0gA:
undetectable
5eeyH-4q0gA:
undetectable		 5eeyG-4q0gA:
9.33
5eeyH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eeyH-4q0gA:
undetectable
5eeyI-4q0gA:
undetectable		 5eeyH-4q0gA:
9.33
5eeyI-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eeyJ-4q0gA:
undetectable
5eeyK-4q0gA:
undetectable		 5eeyJ-4q0gA:
9.33
5eeyK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eeyL-4q0gA:
undetectable
5eeyM-4q0gA:
undetectable		 5eeyL-4q0gA:
9.33
5eeyM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eeyM-4q0gA:
undetectable
5eeyN-4q0gA:
undetectable		 5eeyM-4q0gA:
9.33
5eeyN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eeyN-4q0gA:
undetectable
5eeyO-4q0gA:
undetectable		 5eeyN-4q0gA:
9.33
5eeyO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5eeyO-4q0gA:
undetectable
5eeyP-4q0gA:
undetectable		 5eeyO-4q0gA:
9.33
5eeyP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5eeyP-4q0gA:
undetectable
5eeyQ-4q0gA:
undetectable		 5eeyP-4q0gA:
9.33
5eeyQ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5eeyQ-4q0gA:
undetectable
5eeyR-4q0gA:
undetectable		 5eeyQ-4q0gA:
9.33
5eeyR-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5eeyR-4q0gA:
undetectable
5eeyS-4q0gA:
undetectable		 5eeyR-4q0gA:
9.33
5eeyS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5eeyS-4q0gA:
undetectable
5eeyT-4q0gA:
undetectable		 5eeyS-4q0gA:
9.33
5eeyT-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eeyU-4q0gA:
undetectable
5eeyV-4q0gA:
undetectable		 5eeyU-4q0gA:
9.33
5eeyV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5eezB-4q0gA:
undetectable
5eezC-4q0gA:
undetectable		 5eezB-4q0gA:
9.33
5eezC-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eezD-4q0gA:
undetectable
5eezE-4q0gA:
undetectable		 5eezD-4q0gA:
9.33
5eezE-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.41A 5eezE-4q0gA:
undetectable
5eezF-4q0gA:
undetectable		 5eezE-4q0gA:
9.33
5eezF-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5eezG-4q0gA:
undetectable
5eezH-4q0gA:
undetectable		 5eezG-4q0gA:
9.33
5eezH-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eezH-4q0gA:
undetectable
5eezI-4q0gA:
undetectable		 5eezH-4q0gA:
9.33
5eezI-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5eezJ-4q0gA:
undetectable
5eezK-4q0gA:
undetectable		 5eezJ-4q0gA:
9.33
5eezK-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eezL-4q0gA:
undetectable
5eezM-4q0gA:
undetectable		 5eezL-4q0gA:
9.33
5eezM-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eezM-4q0gA:
undetectable
5eezN-4q0gA:
undetectable		 5eezM-4q0gA:
9.33
5eezN-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5eezN-4q0gA:
undetectable
5eezO-4q0gA:
undetectable		 5eezN-4q0gA:
9.33
5eezO-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5eezO-4q0gA:
undetectable
5eezP-4q0gA:
undetectable		 5eezO-4q0gA:
9.33
5eezP-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5eezP-4q0gA:
undetectable
5eezQ-4q0gA:
undetectable		 5eezP-4q0gA:
9.33
5eezQ-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5eezR-4q0gA:
undetectable
5eezS-4q0gA:
undetectable		 5eezR-4q0gA:
9.33
5eezS-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5eezS-4q0gA:
undetectable
5eezT-4q0gA:
undetectable		 5eezS-4q0gA:
9.33
5eezT-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5eezU-4q0gA:
undetectable
5eezV-4q0gA:
undetectable		 5eezU-4q0gA:
9.33
5eezV-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5ef0B-4q0gA:
undetectable
5ef0C-4q0gA:
undetectable		 5ef0B-4q0gA:
9.33
5ef0C-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef0D-4q0gA:
undetectable
5ef0E-4q0gA:
undetectable		 5ef0D-4q0gA:
9.33
5ef0E-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef0E-4q0gA:
undetectable
5ef0F-4q0gA:
undetectable		 5ef0E-4q0gA:
9.33
5ef0F-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5ef0G-4q0gA:
undetectable
5ef0H-4q0gA:
undetectable		 5ef0G-4q0gA:
9.33
5ef0H-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef0H-4q0gA:
undetectable
5ef0I-4q0gA:
undetectable		 5ef0H-4q0gA:
9.33
5ef0I-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef0J-4q0gA:
undetectable
5ef0K-4q0gA:
undetectable		 5ef0J-4q0gA:
9.33
5ef0K-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef0L-4q0gA:
undetectable
5ef0M-4q0gA:
undetectable		 5ef0L-4q0gA:
9.33
5ef0M-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef0M-4q0gA:
undetectable
5ef0N-4q0gA:
undetectable		 5ef0M-4q0gA:
9.33
5ef0N-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5ef0N-4q0gA:
undetectable
5ef0O-4q0gA:
undetectable		 5ef0N-4q0gA:
9.33
5ef0O-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5ef0O-4q0gA:
undetectable
5ef0P-4q0gA:
undetectable		 5ef0O-4q0gA:
9.33
5ef0P-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5ef0P-4q0gA:
undetectable
5ef0Q-4q0gA:
undetectable		 5ef0P-4q0gA:
9.33
5ef0Q-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5ef0R-4q0gA:
undetectable
5ef0S-4q0gA:
undetectable		 5ef0R-4q0gA:
9.33
5ef0S-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5ef0S-4q0gA:
undetectable
5ef0T-4q0gA:
undetectable		 5ef0S-4q0gA:
9.33
5ef0T-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef0U-4q0gA:
undetectable
5ef0V-4q0gA:
undetectable		 5ef0U-4q0gA:
9.33
5ef0V-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5ef1B-4q0gA:
undetectable
5ef1C-4q0gA:
undetectable		 5ef1B-4q0gA:
9.33
5ef1C-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef1D-4q0gA:
undetectable
5ef1E-4q0gA:
undetectable		 5ef1D-4q0gA:
9.33
5ef1E-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef1E-4q0gA:
undetectable
5ef1F-4q0gA:
undetectable		 5ef1E-4q0gA:
9.33
5ef1F-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5ef1G-4q0gA:
undetectable
5ef1H-4q0gA:
undetectable		 5ef1G-4q0gA:
9.33
5ef1H-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef1H-4q0gA:
undetectable
5ef1I-4q0gA:
undetectable		 5ef1H-4q0gA:
9.33
5ef1I-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef1J-4q0gA:
undetectable
5ef1K-4q0gA:
undetectable		 5ef1J-4q0gA:
9.33
5ef1K-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef1L-4q0gA:
undetectable
5ef1M-4q0gA:
undetectable		 5ef1L-4q0gA:
9.33
5ef1M-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef1M-4q0gA:
undetectable
5ef1N-4q0gA:
undetectable		 5ef1M-4q0gA:
9.33
5ef1N-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5ef1N-4q0gA:
undetectable
5ef1O-4q0gA:
undetectable		 5ef1N-4q0gA:
9.33
5ef1O-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5ef1O-4q0gA:
undetectable
5ef1P-4q0gA:
undetectable		 5ef1O-4q0gA:
9.33
5ef1P-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5ef1P-4q0gA:
undetectable
5ef1Q-4q0gA:
undetectable		 5ef1P-4q0gA:
9.33
5ef1Q-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5ef1R-4q0gA:
undetectable
5ef1S-4q0gA:
undetectable		 5ef1R-4q0gA:
9.33
5ef1S-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5ef1S-4q0gA:
undetectable
5ef1T-4q0gA:
undetectable		 5ef1S-4q0gA:
9.33
5ef1T-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef1U-4q0gA:
undetectable
5ef1V-4q0gA:
undetectable		 5ef1U-4q0gA:
9.33
5ef1V-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5ef2B-4q0gA:
undetectable
5ef2C-4q0gA:
undetectable		 5ef2B-4q0gA:
9.33
5ef2C-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef2D-4q0gA:
undetectable
5ef2E-4q0gA:
undetectable		 5ef2D-4q0gA:
9.33
5ef2E-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef2E-4q0gA:
undetectable
5ef2F-4q0gA:
undetectable		 5ef2E-4q0gA:
9.33
5ef2F-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.37A 5ef2G-4q0gA:
undetectable
5ef2H-4q0gA:
undetectable		 5ef2G-4q0gA:
9.33
5ef2H-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef2H-4q0gA:
undetectable
5ef2I-4q0gA:
undetectable		 5ef2H-4q0gA:
9.33
5ef2I-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 5ef2J-4q0gA:
undetectable
5ef2K-4q0gA:
undetectable		 5ef2J-4q0gA:
9.33
5ef2K-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef2L-4q0gA:
undetectable
5ef2M-4q0gA:
undetectable		 5ef2L-4q0gA:
9.33
5ef2M-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef2M-4q0gA:
undetectable
5ef2N-4q0gA:
undetectable		 5ef2M-4q0gA:
9.33
5ef2N-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5ef2N-4q0gA:
undetectable
5ef2O-4q0gA:
undetectable		 5ef2N-4q0gA:
9.33
5ef2O-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5ef2O-4q0gA:
undetectable
5ef2P-4q0gA:
undetectable		 5ef2O-4q0gA:
9.33
5ef2P-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5ef2P-4q0gA:
undetectable
5ef2Q-4q0gA:
undetectable		 5ef2P-4q0gA:
9.33
5ef2Q-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5ef2R-4q0gA:
undetectable
5ef2S-4q0gA:
undetectable		 5ef2R-4q0gA:
9.33
5ef2S-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5ef2S-4q0gA:
undetectable
5ef2T-4q0gA:
undetectable		 5ef2S-4q0gA:
9.33
5ef2T-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef2U-4q0gA:
undetectable
5ef2V-4q0gA:
undetectable		 5ef2U-4q0gA:
9.33
5ef2V-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.36A 5ef3B-4q0gA:
undetectable
5ef3C-4q0gA:
undetectable		 5ef3B-4q0gA:
9.33
5ef3C-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef3D-4q0gA:
undetectable
5ef3E-4q0gA:
undetectable		 5ef3D-4q0gA:
9.33
5ef3E-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 5ef3E-4q0gA:
undetectable
5ef3F-4q0gA:
undetectable		 5ef3E-4q0gA:
9.33
5ef3F-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.38A 5ef3G-4q0gA:
undetectable
5ef3H-4q0gA:
undetectable		 5ef3G-4q0gA:
9.33
5ef3H-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.40A 5ef3H-4q0gA:
undetectable
5ef3I-4q0gA:
undetectable		 5ef3H-4q0gA:
9.33
5ef3I-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 THR A  87
GLY A  84
ALA A  71
HIS A 119
THR A 115
 None
 1.39A 5ef3J-4q0gA:
undetectable
5ef3K-4q0gA:
undetectable		 5ef3J-4q0gA:
9.33
5ef3K-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef3L-4q0gA:
undetectable
5ef3M-4q0gA:
undetectable		 5ef3L-4q0gA:
9.33
5ef3M-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.36A 5ef3N-4q0gA:
undetectable
5ef3O-4q0gA:
undetectable		 5ef3N-4q0gA:
9.33
5ef3O-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		6 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
ALA A  68
 None
 1.38A 5ef3O-4q0gA:
undetectable
5ef3P-4q0gA:
undetectable		 5ef3O-4q0gA:
9.33
5ef3P-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.33A 5ef3P-4q0gA:
undetectable
5ef3Q-4q0gA:
undetectable		 5ef3P-4q0gA:
9.33
5ef3Q-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.34A 5ef3R-4q0gA:
undetectable
5ef3S-4q0gA:
undetectable		 5ef3R-4q0gA:
9.33
5ef3S-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.35A 5ef3S-4q0gA:
undetectable
5ef3T-4q0gA:
undetectable		 5ef3S-4q0gA:
9.33
5ef3T-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
ALA A  71
HIS A 119
THR A 115
THR A  87
 None
 1.37A 5ef3U-4q0gA:
undetectable
5ef3V-4q0gA:
undetectable		 5ef3U-4q0gA:
9.33
5ef3V-4q0gA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		4 / 5 MET A 418
SER A 417
GLY A 350
ALA A 347
 None
 1.00A 5k50A-4q0gA:
3.6		 5k50A-4q0gA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 9 VAL A 178
LEU A 179
ILE A 256
PRO A 190
ALA A 176
 None
 1.16A 5og9A-4q0gA:
undetectable		 5og9A-4q0gA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 GLY A  84
THR A  87
VAL A 100
ALA A 122
LEU A 492
 None
 1.08A 6czmA-4q0gA:
undetectable
6czmC-4q0gA:
undetectable		 6czmA-4q0gA:
21.56
6czmC-4q0gA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 290
VAL A 287
GLY A 409
ILE A 370
VAL A 297
 None
 0.90A 6dj1B-4q0gA:
undetectable		 6dj1B-4q0gA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 10 ASP A 290
VAL A 287
GLY A 409
ILE A 370
VAL A 297
 None
 0.96A 6dj2A-4q0gA:
undetectable		 6dj2A-4q0gA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 4q0g PROBABLE
ACETYL-/PROPIONYL-CO
A CARBOXYLASE (BETA
SUBUNIT) ACCD1
(Mycobacterium
tuberculosis) 		5 / 12 ASP A 290
VAL A 287
GLY A 409
ILE A 370
VAL A 297
 None
 0.89A 6dj2B-4q0gA:
undetectable		 6dj2B-4q0gA:
13.48