SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 8 VAL A 117
LEU A 200
SER A 196
GLU A 123
 None
 1.11A 1jtvA-4q0sA:
undetectable		 1jtvA-4q0sA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		3 / 3 GLU A 113
HIS A 188
HIS A 108
 CO  A 501 ( 2.4A)
CO  A 501 ( 3.5A)
CO  A 501 ( 3.3A)
 0.71A 1oe2A-4q0sA:
1.3		 1oe2A-4q0sA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 5 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.10A 1os2A-4q0sA:
undetectable		 1os2A-4q0sA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.11A 1os2D-4q0sA:
undetectable		 1os2D-4q0sA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 7 GLU A 204
HIS A 108
MET A  63
ILE A  65
 RB0  A 502 (-3.1A)
CO  A 501 ( 3.3A)
RB0  A 502 ( 4.4A)
None
 0.93A 1tuvA-4q0sA:
undetectable		 1tuvA-4q0sA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.13A 1utzA-4q0sA:
undetectable		 1utzA-4q0sA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B82_B_ADNB1002_1
(CLASS B ACID
PHOSPHATASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		5 / 9 PHE A 125
GLU A  61
TYR A 164
LEU A 156
GLY A 153
 None
 1.46A 2b82B-4q0sA:
undetectable		 2b82B-4q0sA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.12A 2hu6A-4q0sA:
undetectable		 2hu6A-4q0sA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.13A 2ow9B-4q0sA:
undetectable		 2ow9B-4q0sA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.12A 2ozrC-4q0sA:
undetectable		 2ozrC-4q0sA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.09A 2ozrD-4q0sA:
undetectable		 2ozrD-4q0sA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		5 / 12 GLY A 242
ALA A 238
ARG A 160
GLU A  61
ALA A 247
 None
 1.06A 3g89A-4q0sA:
undetectable		 3g89A-4q0sA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 5 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.14A 3likA-4q0sA:
undetectable		 3likA-4q0sA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 5 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.11A 3lkaA-4q0sA:
undetectable		 3lkaA-4q0sA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		5 / 9 ALA A  18
TYR A  47
ILE A   6
GLY A  39
ALA A  38
 None
 1.21A 4r1zA-4q0sA:
undetectable		 4r1zA-4q0sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		3 / 3 ASP A 197
LEU A 119
GLY A 120
 None
 0.49A 4xmfA-4q0sA:
undetectable		 4xmfA-4q0sA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 7 ALA A  49
ARG A 243
GLY A 242
THR A 213
 None
RB0  A 502 (-3.8A)
None
None
 0.81A 5bs8A-4q0sA:
undetectable
5bs8C-4q0sA:
undetectable
5bs8D-4q0sA:
undetectable		 5bs8A-4q0sA:
17.68
5bs8C-4q0sA:
17.68
5bs8D-4q0sA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 6 ALA A  49
ARG A 243
GLY A 242
THR A 213
 None
RB0  A 502 (-3.8A)
None
None
 0.78A 5btgA-4q0sA:
undetectable
5btgB-4q0sA:
undetectable
5btgC-4q0sA:
undetectable		 5btgA-4q0sA:
17.68
5btgB-4q0sA:
21.40
5btgC-4q0sA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 CO  A 501 ( 3.5A)
CO  A 501 ( 2.4A)
CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
 1.15A 5n5jA-4q0sA:
undetectable		 5n5jA-4q0sA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 106
HIS A 188
TYR A 115
GLU A 113
 CO  A 501 ( 3.5A)
CO  A 501 ( 3.5A)
None
CO  A 501 ( 2.4A)
 1.27A 5pahA-4q0sA:
undetectable		 5pahA-4q0sA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 4 HIS A 108
HIS A 188
TYR A 115
GLU A 113
 CO  A 501 ( 3.3A)
CO  A 501 ( 3.5A)
None
CO  A 501 ( 2.4A)
 1.17A 5pahA-4q0sA:
undetectable		 5pahA-4q0sA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		4 / 5 PHE A 234
THR A 241
ASP A  45
GLU A  61
 None
 1.12A 5ybbA-4q0sA:
undetectable		 5ybbA-4q0sA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 4q0s L-RIBOSE ISOMERASE
(Acinetobacter
sp.
DL-28) 		3 / 3 HIS A 106
HIS A 188
HIS A 108
 CO  A 501 ( 3.5A)
CO  A 501 ( 3.5A)
CO  A 501 ( 3.3A)
 0.37A 5zrdA-4q0sA:
undetectable		 5zrdA-4q0sA:
18.63