SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q1l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		5 / 11 LEU A  56
LEU A  37
VAL A  33
MET A 140
LEU A  98
 None
 1.29A 1kt7A-4q1lA:
undetectable		 1kt7A-4q1lA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.22A 1os2A-4q1lA:
10.8		 1os2A-4q1lA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.18A 1os2D-4q1lA:
10.8		 1os2D-4q1lA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 5 LEU A  98
TRP A  81
LEU A  56
GLN A  96
 None
 1.44A 1p93D-4q1lA:
undetectable		 1p93D-4q1lA:
20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		6 / 10 THR A 107
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
None
ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.23A 1r55A-4q1lA:
31.4		 1r55A-4q1lA:
36.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.19A 1uttA-4q1lA:
11.2		 1uttA-4q1lA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.23A 1utzA-4q1lA:
11.1		 1utzA-4q1lA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.22A 1utzB-4q1lA:
11.1		 1utzB-4q1lA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		3 / 3 ASP A 153
GLU A 143
ARG A 135
 None
ZN  A 302 ( 4.7A)
None
 0.86A 1wopA-4q1lA:
undetectable		 1wopA-4q1lA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.17A 1y93A-4q1lA:
11.3		 1y93A-4q1lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.14A 2hu6A-4q1lA:
11.1		 2hu6A-4q1lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.29A 2jihA-4q1lA:
26.1		 2jihA-4q1lA:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		5 / 8 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.30A 2jihB-4q1lA:
25.9		 2jihB-4q1lA:
26.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.28A 2ow9A-4q1lA:
10.7		 2ow9A-4q1lA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.27A 2ow9B-4q1lA:
10.5		 2ow9B-4q1lA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.29A 2ozrC-4q1lA:
10.3		 2ozrC-4q1lA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.33A 2ozrD-4q1lA:
10.4		 2ozrD-4q1lA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.36A 2ozrE-4q1lA:
10.4		 2ozrE-4q1lA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		3 / 3 HIS A 142
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.31A 2ozrF-4q1lA:
10.3		 2ozrF-4q1lA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		5 / 9 HIS A 142
GLU A 143
HIS A 146
HIS A 152
LEU A 170
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
None
 0.76A 3hy7A-4q1lA:
26.4		 3hy7A-4q1lA:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.21A 3hy7A-4q1lA:
26.4		 3hy7A-4q1lA:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		6 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
LEU A 170
 None
ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
None
 0.62A 3hy7B-4q1lA:
26.2		 3hy7B-4q1lA:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_D_VIAD901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		5 / 11 GLN A 185
HIS A 142
ALA A 124
PHE A 178
MET A  47
 None
ZN  A 302 (-3.2A)
None
None
None
 1.47A 3jwqA-4q1lA:
undetectable
3jwqD-4q1lA:
undetectable		 3jwqA-4q1lA:
21.39
3jwqD-4q1lA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.25A 3kecA-4q1lA:
10.6		 3kecA-4q1lA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		3 / 3 HIS A 142
GLU A 143
HIS A 146
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
 0.20A 3kecB-4q1lA:
10.4		 3kecB-4q1lA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 5 ILE A 110
PHE A 103
ASP A 104
GLU A 105
 None
 1.18A 3kp6A-4q1lA:
undetectable
3kp6B-4q1lA:
undetectable		 3kp6A-4q1lA:
20.39
3kp6B-4q1lA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.16A 3likA-4q1lA:
11.3		 3likA-4q1lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.16A 3lilA-4q1lA:
11.2		 3lilA-4q1lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.14A 3ljgA-4q1lA:
11.3		 3ljgA-4q1lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.16A 3lkaA-4q1lA:
11.1		 3lkaA-4q1lA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.36A 4a7bA-4q1lA:
10.5		 4a7bA-4q1lA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 6 LEU A  56
MET A  36
MET A 140
LEU A  10
 None
 0.84A 4okxA-4q1lA:
undetectable		 4okxA-4q1lA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 LEU A 170
ILE A 165
HIS A 142
VAL A 138
 None
None
ZN  A 302 (-3.2A)
None
 1.16A 4xyzA-4q1lA:
undetectable		 4xyzA-4q1lA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.16A 5n5jA-4q1lA:
11.2		 5n5jA-4q1lA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 302 (-3.2A)
ZN  A 302 ( 4.7A)
ZN  A 302 (-3.1A)
ZN  A 302 (-3.1A)
 0.18A 5n5kA-4q1lA:
11.2		 5n5kA-4q1lA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 7 SER A 122
GLY A 115
ARG A  82
LEU A  87
 EDO  A 304 ( 4.7A)
None
EDO  A 304 (-2.6A)
None
 1.10A 6btxA-4q1lA:
undetectable		 6btxA-4q1lA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A
(Bothrops
leucurus) 		4 / 4 HIS A  92
VAL A  13
LEU A  86
ALA A  95
 None
 1.44A 6d8pB-4q1lA:
4.7		 6d8pB-4q1lA:
12.71