SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 6 TYR A 274
GLY A 251
TYR A 255
ASN A 270
 None
 1.17A 2g72A-4q1qA:
undetectable		 2g72A-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 ILE A 122
ALA A 183
GLY A 163
GLY A 145
ASN A 161
 None
None
289  A 421 ( 4.3A)
None
None
 1.18A 2okcB-4q1qA:
undetectable		 2okcB-4q1qA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 11 GLN A 204
THR A 215
THR A 234
ARG A 207
GLY A 229
 None
None
None
289  A 414 ( 3.6A)
None
 1.31A 3abkA-4q1qA:
undetectable
3abkB-4q1qA:
undetectable
3abkT-4q1qA:
undetectable		 3abkA-4q1qA:
21.89
3abkB-4q1qA:
19.41
3abkT-4q1qA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 11 GLN A 204
THR A 215
THR A 234
ARG A 207
GLY A 229
 None
None
None
289  A 414 ( 3.6A)
None
 1.28A 3ag3A-4q1qA:
undetectable
3ag3B-4q1qA:
undetectable
3ag3T-4q1qA:
undetectable		 3ag3A-4q1qA:
21.89
3ag3B-4q1qA:
19.41
3ag3T-4q1qA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 11 ARG A 207
GLY A 229
GLN A 204
THR A 215
THR A 234
 289  A 414 ( 3.6A)
None
None
None
None
 1.37A 3ag3G-4q1qA:
undetectable
3ag3N-4q1qA:
undetectable
3ag3O-4q1qA:
undetectable		 3ag3G-4q1qA:
12.16
3ag3N-4q1qA:
21.89
3ag3O-4q1qA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 GLY A 191
VAL A 111
GLY A 152
ALA A 155
ALA A 136
 None
None
289  A 408 (-4.4A)
None
None
 1.10A 3keeB-4q1qA:
undetectable		 3keeB-4q1qA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 GLY A 304
VAL A 225
GLY A 265
ALA A 268
ALA A 249
 289  A 435 ( 4.8A)
None
289  A 415 ( 3.7A)
None
None
 1.11A 3keeB-4q1qA:
undetectable		 3keeB-4q1qA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 GLY A 191
VAL A 111
GLY A 152
ALA A 155
ALA A 136
 None
None
289  A 408 (-4.4A)
None
None
 1.07A 3keeC-4q1qA:
undetectable		 3keeC-4q1qA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 GLY A 304
VAL A 225
GLY A 265
ALA A 268
ALA A 249
 289  A 435 ( 4.8A)
None
289  A 415 ( 3.7A)
None
None
 1.09A 3keeC-4q1qA:
undetectable		 3keeC-4q1qA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 TYR A 261
GLY A 247
ALA A 249
THR A 234
ILE A 236
 None
 1.39A 3ld6A-4q1qA:
undetectable		 3ld6A-4q1qA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 TYR A  91
GLY A  96
ALA A  98
THR A 101
ILE A  84
 289  A 405 (-4.7A)
None
None
None
None
 1.40A 3ld6B-4q1qA:
undetectable		 3ld6B-4q1qA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 TYR A 261
GLY A 266
ALA A 268
THR A 271
ILE A 254
 None
 1.39A 3ld6B-4q1qA:
undetectable		 3ld6B-4q1qA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 GLY A 191
GLY A 229
THR A 213
ALA A 232
ASP A 214
 None
None
None
289  A 416 (-3.5A)
None
 1.10A 3sugA-4q1qA:
undetectable		 3sugA-4q1qA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 TYR A 205
GLY A 201
GLY A 221
LEU A 217
ASN A 199
 289  A 414 (-4.6A)
289  A 422 ( 4.0A)
None
None
None
 0.95A 3vywA-4q1qA:
undetectable		 3vywA-4q1qA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 TYR A 205
GLY A 201
GLY A 221
LEU A 217
ASN A 199
 289  A 414 (-4.6A)
289  A 422 ( 4.0A)
None
None
None
 0.95A 3vywD-4q1qA:
undetectable		 3vywD-4q1qA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 8 SER A 267
ALA A 232
SER A 248
THR A 250
 289  A 417 (-2.6A)
289  A 416 (-3.5A)
289  A 417 (-1.3A)
289  A 416 ( 2.7A)
 0.93A 4iklA-4q1qA:
undetectable
4iklB-4q1qA:
undetectable		 4iklA-4q1qA:
17.88
4iklB-4q1qA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 LEU A 217
GLN A 223
LEU A 244
THR A 271
VAL A 287
 None
 1.36A 4okxA-4q1qA:
undetectable		 4okxA-4q1qA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		3 / 3 THR A 180
ASN A 161
SER A 162
 None
None
289  A 421 ( 1.3A)
 0.59A 4tvtA-4q1qA:
undetectable		 4tvtA-4q1qA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 11 ARG A 207
GLY A 229
GLN A 204
THR A 215
THR A 234
 289  A 414 ( 3.6A)
None
None
None
None
 1.35A 5b1bG-4q1qA:
undetectable
5b1bN-4q1qA:
undetectable
5b1bO-4q1qA:
undetectable		 5b1bG-4q1qA:
12.16
5b1bN-4q1qA:
21.89
5b1bO-4q1qA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		6 / 12 GLY A 228
VAL A 206
ALA A 212
THR A 215
ALA A 232
GLY A 221
 None
None
None
None
289  A 416 (-3.5A)
None
 1.32A 5hesA-4q1qA:
undetectable		 5hesA-4q1qA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		6 / 12 GLY A 228
VAL A 206
ALA A 212
THR A 215
ALA A 249
GLY A 202
 None
 1.44A 5hesB-4q1qA:
undetectable		 5hesB-4q1qA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		6 / 12 GLY A 228
VAL A 206
ALA A 212
THR A 215
ALA A 249
GLY A 221
 None
 1.45A 5hesB-4q1qA:
undetectable		 5hesB-4q1qA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 135
ALA A 136
GLN A 166
THR A 139
 289  A 434 (-1.4A)
None
None
None
 1.25A 5n0rA-4q1qA:
undetectable		 5n0rA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 154
ALA A 155
GLN A 185
THR A 158
 289  A 410 ( 1.3A)
None
None
None
 1.22A 5n0rA-4q1qA:
undetectable		 5n0rA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 135
ALA A 136
GLN A 166
THR A 139
 289  A 434 (-1.4A)
None
None
None
 1.21A 5n0sA-4q1qA:
undetectable		 5n0sA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 154
ALA A 155
GLN A 185
THR A 158
 289  A 410 ( 1.3A)
None
None
None
 1.18A 5n0sA-4q1qA:
undetectable		 5n0sA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 230
ALA A 231
GLN A 260
THR A 234
 289  A 416 (-1.3A)
None
None
None
 1.26A 5n0sA-4q1qA:
undetectable		 5n0sA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 SER A 135
ALA A 136
GLN A 166
THR A 139
 289  A 434 (-1.4A)
None
None
None
 1.24A 5n0tA-4q1qA:
undetectable		 5n0tA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 SER A 154
ALA A 155
GLN A 185
THR A 158
 289  A 410 ( 1.3A)
None
None
None
 1.21A 5n0tA-4q1qA:
undetectable		 5n0tA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 135
ALA A 136
GLN A 166
THR A 139
 289  A 434 (-1.4A)
None
None
None
 1.24A 5n0wA-4q1qA:
undetectable		 5n0wA-4q1qA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 154
ALA A 155
GLN A 185
THR A 158
 289  A 410 ( 1.3A)
None
None
None
 1.21A 5n0wA-4q1qA:
undetectable		 5n0wA-4q1qA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 230
ALA A 231
GLN A 260
THR A 234
 289  A 416 (-1.3A)
None
None
None
 1.29A 5n0wA-4q1qA:
undetectable		 5n0wA-4q1qA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 SER A 135
ALA A 136
GLN A 166
THR A 139
 289  A 434 (-1.4A)
None
None
None
 1.26A 5n0wB-4q1qA:
undetectable		 5n0wB-4q1qA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 SER A 154
ALA A 155
GLN A 185
THR A 158
 289  A 410 ( 1.3A)
None
None
None
 1.23A 5n0wB-4q1qA:
undetectable		 5n0wB-4q1qA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 SER A 230
ALA A 231
GLN A 260
THR A 234
 289  A 416 (-1.3A)
None
None
None
 1.30A 5n0wB-4q1qA:
undetectable		 5n0wB-4q1qA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 135
ALA A 136
GLN A 166
THR A 139
 289  A 434 (-1.4A)
None
None
None
 1.26A 5n0xA-4q1qA:
undetectable		 5n0xA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 4 SER A 154
ALA A 155
GLN A 185
THR A 158
 289  A 410 ( 1.3A)
None
None
None
 1.23A 5n0xA-4q1qA:
undetectable		 5n0xA-4q1qA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 SER A 135
ALA A 136
GLN A 166
THR A 139
 289  A 434 (-1.4A)
None
None
None
 1.24A 5n4iA-4q1qA:
undetectable		 5n4iA-4q1qA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 SER A 154
ALA A 155
GLN A 185
THR A 158
 289  A 410 ( 1.3A)
None
None
None
 1.21A 5n4iA-4q1qA:
undetectable		 5n4iA-4q1qA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 SER A 230
ALA A 231
GLN A 260
THR A 234
 289  A 416 (-1.3A)
None
None
None
 1.28A 5n4iA-4q1qA:
undetectable		 5n4iA-4q1qA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 12 GLY A 221
SER A 178
ILE A 160
GLY A 201
GLY A 202
 None
None
None
289  A 422 ( 4.0A)
None
 0.95A 5wyqB-4q1qA:
undetectable		 5wyqB-4q1qA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		5 / 9 SER A 211
GLY A 228
ALA A 249
SER A 248
GLY A 247
 289  A 416 (-2.7A)
None
None
289  A 417 (-1.3A)
None
 1.17A 6bklE-4q1qA:
undetectable
6bklF-4q1qA:
undetectable
6bklG-4q1qA:
undetectable
6bklH-4q1qA:
undetectable		 6bklE-4q1qA:
4.92
6bklF-4q1qA:
4.92
6bklG-4q1qA:
4.92
6bklH-4q1qA:
4.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 THR A 139
THR A  82
GLN A  90
ASP A  58
 None
 1.27A 6ectA-4q1qA:
undetectable		 6ectA-4q1qA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 4q1q ADHESIN/INVASIN TIBA
AUTOTRANSPORTER
(Escherichia
coli) 		4 / 5 THR A 139
THR A  82
GLN A  90
ASP A  58
 None
 1.36A 6ecxA-4q1qA:
undetectable		 6ecxA-4q1qA:
21.81