SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q1t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 4q1t GLUTAMATE 5-KINASE
(Burkholderia
thailandensis) 		4 / 5 GLU A  48
THR A 124
LEU A 128
LEU A 125
 None
 1.06A 1u18B-4q1tA:
undetectable		 1u18B-4q1tA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 4q1t GLUTAMATE 5-KINASE
(Burkholderia
thailandensis) 		3 / 3 GLY A  26
GLU A  59
ASN A  22
 None
 0.56A 1zq9A-4q1tA:
4.2		 1zq9A-4q1tA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4q1t GLUTAMATE 5-KINASE
(Burkholderia
thailandensis) 		5 / 12 LEU A 125
LEU A 107
GLY A 157
ALA A 161
ALA A 233
 None
 1.16A 2bm9D-4q1tA:
2.8		 2bm9D-4q1tA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 4q1t GLUTAMATE 5-KINASE
(Burkholderia
thailandensis) 		4 / 8 ASP A 141
GLY A  83
ALA A  79
ILE A  57
 None
 0.77A 2dtjA-4q1tA:
undetectable
2dtjB-4q1tA:
undetectable		 2dtjA-4q1tA:
20.63
2dtjB-4q1tA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 4q1t GLUTAMATE 5-KINASE
(Burkholderia
thailandensis) 		3 / 3 GLU A  48
ASP A 167
ASP A 367
 None
 0.76A 3jb2A-4q1tA:
3.0		 3jb2A-4q1tA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 4q1t GLUTAMATE 5-KINASE
(Burkholderia
thailandensis) 		5 / 12 GLY A 198
ALA A 225
ALA A 233
ALA A 168
SER A   8
 None
 1.03A 3sudD-4q1tA:
undetectable		 3sudD-4q1tA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 4q1t GLUTAMATE 5-KINASE
(Burkholderia
thailandensis) 		4 / 5 LEU A 246
ALA A  37
VAL A 134
ILE A 100
 None
 0.88A 4xe3A-4q1tA:
undetectable		 4xe3A-4q1tA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4q1t GLUTAMATE 5-KINASE
(Burkholderia
thailandensis) 		5 / 10 ILE A 222
ILE A   5
ALA A 168
LEU A 169
ALA A 161
 None
 1.37A 5zjiB-4q1tA:
undetectable		 5zjiB-4q1tA:
11.99