SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 376
ARG A 346
ILE A 108
 None
UNX  A 400 ( 4.2A)
None
 0.61A 1a4gB-4q1zA:
undetectable		 1a4gB-4q1zA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GEB_A_CAMA418_0
(CYTOCHROME P450-CAM)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 PHE A 224
TYR A 256
THR A 258
ILE A 267
ILE A 197
 None
 1.35A 1gebA-4q1zA:
undetectable		 1gebA-4q1zA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 10 ILE A 196
ASN A 396
GLY A 217
PHE A 130
ALA A 235
 None
 1.45A 1ju6C-4q1zA:
undetectable		 1ju6C-4q1zA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 333
PHE A 377
SER A 373
VAL A 306
VAL A 324
 None
 1.25A 1q23C-4q1zA:
undetectable		 1q23C-4q1zA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A 231
TYR A 125
LYS A 121
TYR A 209
 None
 1.42A 1xqlA-4q1zA:
undetectable
1xqlB-4q1zA:
undetectable		 1xqlA-4q1zA:
22.94
1xqlB-4q1zA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS A 121
TYR A 209
PHE A 231
TYR A 125
 None
 1.38A 1xqlA-4q1zA:
undetectable
1xqlB-4q1zA:
undetectable		 1xqlA-4q1zA:
22.94
1xqlB-4q1zA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A 224
TYR A 256
THR A 258
ILE A 197
 None
 0.69A 2a1mB-4q1zA:
undetectable		 2a1mB-4q1zA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 THR A 398
ASP A 216
GLU A 223
SER A 220
 None
None
UNX  A 401 ( 3.4A)
None
 0.82A 2zw9A-4q1zA:
undetectable		 2zw9A-4q1zA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 GLY A 343
GLU A 111
GLY A 380
PRO A 383
 None
 1.01A 3onnA-4q1zA:
undetectable		 3onnA-4q1zA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.31A 4jksA-4q1zA:
undetectable		 4jksA-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.30A 4jksB-4q1zA:
undetectable		 4jksB-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.32A 4jkuA-4q1zA:
undetectable		 4jkuA-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_2
(SUGAR KINASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.31A 4k8cB-4q1zA:
undetectable		 4k8cB-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_2
(SUGAR KINASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.32A 4k8kA-4q1zA:
undetectable		 4k8kA-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.33A 4k8kB-4q1zA:
undetectable		 4k8kB-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.32A 4kalA-4q1zA:
undetectable		 4kalA-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.31A 4kalB-4q1zA:
undetectable		 4kalB-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A 224
TYR A 256
THR A 258
ILE A 197
 None
 0.88A 4l4cB-4q1zA:
undetectable		 4l4cB-4q1zA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.32A 4lcaA-4q1zA:
undetectable		 4lcaA-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 117
LEU A 257
TYR A 125
PRO A 383
 None
 1.33A 4lcaB-4q1zA:
undetectable		 4lcaB-4q1zA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 238
VAL A 242
ASN A 227
 UNX  A 401 ( 3.0A)
None
None
 0.68A 4lmnA-4q1zA:
undetectable		 4lmnA-4q1zA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 253
HIS A 204
TYR A 339
VAL A 260
 None
 1.28A 4s0vA-4q1zA:
undetectable		 4s0vA-4q1zA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 148
ILE A 267
GLY A 145
PHE A 180
 None
 0.92A 5h3aA-4q1zA:
undetectable		 5h3aA-4q1zA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A 380
ASP A 329
ILE A 108
TYR A 114
 None
 1.07A 5iwuA-4q1zA:
2.3		 5iwuA-4q1zA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 354
ASP A 351
ASN A  80
 None
 0.60A 5jglA-4q1zA:
undetectable		 5jglA-4q1zA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 4q1z PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 PRO A 383
VAL A 384
ALA A 345
PHE A 130
 None
None
PEG  A 403 ( 3.8A)
None
 0.98A 5t7bA-4q1zA:
undetectable		 5t7bA-4q1zA:
17.95