SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4q29 PLU4264 PROTEIN
(Photorhabdus
laumondii) 		4 / 4 HIS A  90
GLU A  56
HIS A  52
HIS A  50
 NI  A 201 (-3.2A)
NI  A 201 (-2.5A)
NI  A 201 (-3.4A)
NI  A 201 (-3.3A)
 1.20A 2hu6A-4q29A:
undetectable		 2hu6A-4q29A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 4q29 PLU4264 PROTEIN
(Photorhabdus
laumondii) 		4 / 4 HIS A  90
GLU A  56
HIS A  52
HIS A  50
 NI  A 201 (-3.2A)
NI  A 201 (-2.5A)
NI  A 201 (-3.4A)
NI  A 201 (-3.3A)
 1.14A 2ozrD-4q29A:
undetectable		 2ozrD-4q29A:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4q29 PLU4264 PROTEIN
(Photorhabdus
laumondii) 		4 / 7 ALA A  65
ILE A  93
ILE A  67
HIS A  91
 None
 1.16A 2zm7A-4q29A:
undetectable		 2zm7A-4q29A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4q29 PLU4264 PROTEIN
(Photorhabdus
laumondii) 		5 / 12 GLY A  36
GLY A  21
SER A  22
ASP A  20
LEU A  19
 None
 1.18A 3ou7A-4q29A:
undetectable		 3ou7A-4q29A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4q29 PLU4264 PROTEIN
(Photorhabdus
laumondii) 		5 / 12 GLY A  36
GLY A  21
SER A  22
ASP A  20
LEU A  19
 None
 1.19A 3ou7D-4q29A:
undetectable		 3ou7D-4q29A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAH_A_LNRA600_1
(PHENYLALANINE
HYDROXYLASE)		 4q29 PLU4264 PROTEIN
(Photorhabdus
laumondii) 		4 / 6 PHE A 102
HIS A  50
HIS A  90
GLU A  56
 None
NI  A 201 (-3.3A)
NI  A 201 (-3.2A)
NI  A 201 (-2.5A)
 1.06A 4pahA-4q29A:
undetectable		 4pahA-4q29A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4q29 PLU4264 PROTEIN
(Photorhabdus
laumondii) 		4 / 4 HIS A  90
GLU A  56
HIS A  52
HIS A  50
 NI  A 201 (-3.2A)
NI  A 201 (-2.5A)
NI  A 201 (-3.4A)
NI  A 201 (-3.3A)
 1.20A 5n5jA-4q29A:
undetectable		 5n5jA-4q29A:
19.63