SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q2j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4q2j DNA-BINDING PROTEIN
SATB1
(Mus
musculus) 		3 / 3 LEU A 106
LEU A  74
MET A  73
 None
 0.76A 2itzA-4q2jA:
undetectable		 2itzA-4q2jA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4q2j DNA-BINDING PROTEIN
SATB1
(Mus
musculus) 		5 / 11 LEU A 170
ALA A 126
ALA A 125
VAL A  80
LEU A 118
 None
 1.11A 3bszE-4q2jA:
undetectable		 3bszE-4q2jA:
22.22