SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q2m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KFJ_B_FOLB202_0 (DIHYDROFOLATE REDUCTASE)	4q2m	MAJOR FACILITATOR SUPERFAMILY MFS_1 (Escherichia coli)	5 / 12	ILE A 14 PRO A 15 LEU A 24 VAL A 37 THR A 55	None	0.99A	4kfjB-4q2mA: undetectable	4kfjB-4q2mA: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_C_ACTC401_0 (PROTON-GATED ION CHANNEL)	4q2m	MAJOR FACILITATOR SUPERFAMILY MFS_1 (Escherichia coli)	4 / 7	ILE A 50 ARG A 57 VAL A 60 ILE A 12	None IOD A3013 (-4.4A) None None	0.97A	4zzbC-4q2mA: undetectable 4zzbD-4q2mA: undetectable	4zzbC-4q2mA: 13.09 4zzbD-4q2mA: 13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_0 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	4q2m	MAJOR FACILITATOR SUPERFAMILY MFS_1 (Escherichia coli)	4 / 8	ILE A 64 THR A 55 VAL A 54 GLU A 32	None	1.10A	6fbvC-4q2mA: undetectable	6fbvC-4q2mA: 4.85