SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q2s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 4q2s PDC1 GE1 DOMAIN
(Schizosaccharomy
ces
pombe) 		5 / 11 GLY A 949
SER A 971
LEU A 970
LEU A 942
CYH A 954
 None
 1.01A 2qmmA-4q2sA:
undetectable
2qmmB-4q2sA:
undetectable		 2qmmA-4q2sA:
21.05
2qmmB-4q2sA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 4q2s PDC1 GE1 DOMAIN
(Schizosaccharomy
ces
pombe) 		5 / 9 GLY A 949
SER A 971
LEU A 970
LEU A 942
CYH A 954
 None
 0.97A 3ai9X-4q2sA:
undetectable		 3ai9X-4q2sA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4q2s PDC1 GE1 DOMAIN
(Schizosaccharomy
ces
pombe) 		4 / 5 LEU A1059
LEU A1041
LEU A1005
SER A1006
 None
 0.99A 3vhuA-4q2sA:
undetectable		 3vhuA-4q2sA:
22.97