SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q2w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 8 PHE A 169
GLY A 194
VAL A 225
ILE A 229
 None
 0.81A 2a1mB-4q2wA:
undetectable		 2a1mB-4q2wA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 ASN A 130
PHE A 134
ALA A 270
GLY A 266
 None
 1.18A 3bcrA-4q2wA:
undetectable		 3bcrA-4q2wA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 10 PHE A 206
ILE A 269
ALA A 180
ILE A 276
VAL A 272
 None
 1.00A 3me6A-4q2wA:
undetectable		 3me6A-4q2wA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ALA A 260
GLY A 266
LEU A 137
GLU A 190
TYR A 240
 None
None
None
None
GOL  A 302 (-4.8A)
 1.08A 3o7wA-4q2wA:
undetectable		 3o7wA-4q2wA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 ASP A 119
VAL A 102
ILE A 100
SER A 117
 None
 0.95A 3pglA-4q2wA:
undetectable		 3pglA-4q2wA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 ILE A 178
LEU A 183
PHE A 206
GLY A 228
 None
 0.93A 3sj1X-4q2wA:
undetectable		 3sj1X-4q2wA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 LEU A 230
GLY A 231
PHE A 169
ASN A 203
 None
 0.95A 3uq6B-4q2wA:
undetectable		 3uq6B-4q2wA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 7 PHE A 247
PHE A 134
ALA A 252
LEU A 121
 None
 0.90A 4ejgC-4q2wA:
undetectable		 4ejgC-4q2wA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A 121
GLY A 120
SER A  62
TYR A 264
ASN A 250
 None
 1.23A 5czyA-4q2wA:
undetectable		 5czyA-4q2wA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ILE A 229
LEU A 162
GLU A 173
PHE A 169
ASN A 179
 None
None
GOL  A 303 ( 4.9A)
None
None
 1.35A 5il1A-4q2wA:
undetectable		 5il1A-4q2wA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 ILE A 229
LEU A 162
GLU A 173
PHE A 169
ASN A 179
 None
None
GOL  A 303 ( 4.9A)
None
None
 1.32A 5k7uA-4q2wA:
undetectable		 5k7uA-4q2wA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		5 / 12 PHE A 206
ALA A 232
ILE A 178
GLY A 166
LEU A 162
 None
 1.12A 5m24A-4q2wA:
undetectable		 5m24A-4q2wA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 5 ALA A  22
VAL A  24
LYS A  66
ILE A  56
 None
 0.93A 5of1A-4q2wA:
undetectable		 5of1A-4q2wA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 4q2w PUTATIVE
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
(Streptococcus
pneumoniae) 		4 / 6 ILE A 276
MET A 273
ASN A 277
ASP A 284
 None
 1.25A 6dhbA-4q2wA:
undetectable		 6dhbA-4q2wA:
15.22