SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 4q3m MGS-M4
(unidentified) 		4 / 8 SER A 197
LEU A 196
ILE A 215
ILE A 212
 None
 0.97A 1sbrA-4q3mA:
undetectable		 1sbrA-4q3mA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_A_ADNA1501_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 4q3m MGS-M4
(unidentified) 		4 / 7 GLU A  11
LYS A 131
ASN A   8
ALA A 132
 None
 1.34A 2ejgA-4q3mA:
undetectable		 2ejgA-4q3mA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 4q3m MGS-M4
(unidentified) 		3 / 3 ASN A 137
ASN A 139
GLU A 268
 None
 0.84A 3kpdC-4q3mA:
undetectable		 3kpdC-4q3mA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R43_A_ID8A332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		6 / 12 TYR A  48
TRP A  75
HIS A 106
ASN A 137
TYR A 184
PHE A 266
 None
 0.58A 3r43A-4q3mA:
38.7		 3r43A-4q3mA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R58_A_NPSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		5 / 10 TYR A  48
HIS A 106
ASN A 137
TYR A 184
PHE A 266
 None
 0.38A 3r58A-4q3mA:
39.0		 3r58A-4q3mA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R6I_A_JMSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		6 / 12 TYR A  48
TRP A  75
HIS A 106
ASN A 137
TYR A 184
PHE A 266
 None
 0.51A 3r6iA-4q3mA:
39.0		 3r6iA-4q3mA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R7M_A_SUZA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		5 / 10 TYR A  48
TRP A  75
HIS A 106
ASN A 137
PHE A 266
 None
 0.56A 3r7mA-4q3mA:
38.9		 3r7mA-4q3mA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R8G_A_IZPA409_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		5 / 9 TYR A  48
HIS A 106
ASN A 137
TYR A 184
PHE A 266
 None
 0.52A 3r8gA-4q3mA:
38.9		 3r8gA-4q3mA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		5 / 12 TYR A  48
HIS A 106
ASN A 137
TYR A 184
PHE A 266
 None
 0.49A 3r94A-4q3mA:
38.8		 3r94A-4q3mA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		5 / 12 TYR A  48
TRP A  75
HIS A 106
ASN A 137
TYR A 184
 None
 0.30A 3ug8A-4q3mA:
38.8		 3ug8A-4q3mA:
38.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 4q3m MGS-M4
(unidentified) 		5 / 12 GLY A  37
ILE A  68
ILE A  15
VAL A 243
ILE A 217
 None
 0.97A 4q5mA-4q3mA:
undetectable		 4q5mA-4q3mA:
22.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVV_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		6 / 9 TYR A  48
TRP A  75
HIS A 106
ASN A 137
TYR A 184
PHE A 266
 None
 0.53A 4yvvA-4q3mA:
38.6		 4yvvA-4q3mA:
37.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVV_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		5 / 9 TYR A  48
TRP A  75
HIS A 106
ASN A 137
PHE A 266
 None
 0.49A 4yvvB-4q3mA:
38.6		 4yvvB-4q3mA:
37.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZFC_A_GCZA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		5 / 9 TYR A  48
TRP A  75
HIS A 106
ASN A 137
PHE A 266
 None
 0.57A 4zfcA-4q3mA:
38.5		 4zfcA-4q3mA:
37.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZFC_B_GCZB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4q3m MGS-M4
(unidentified) 		5 / 9 TYR A  48
TRP A  75
HIS A 106
ASN A 137
PHE A 266
 None
 0.53A 4zfcB-4q3mA:
38.4		 4zfcB-4q3mA:
37.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4q3m MGS-M4
(unidentified) 		5 / 11 HIS A  41
THR A  44
THR A  72
THR A  71
GLY A  55
 None
 1.31A 5bxnV-4q3mA:
undetectable
5bxnb-4q3mA:
undetectable		 5bxnV-4q3mA:
23.73
5bxnb-4q3mA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4q3m MGS-M4
(unidentified) 		5 / 11 HIS A  41
THR A  44
THR A  72
THR A  71
GLY A  55
 None
 1.33A 5bxnH-4q3mA:
undetectable
5bxnN-4q3mA:
undetectable		 5bxnH-4q3mA:
23.73
5bxnN-4q3mA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4q3m MGS-M4
(unidentified) 		4 / 5 THR A  44
ALA A  45
THR A  72
TYR A 103
 None
 1.01A 5ecmA-4q3mA:
1.6		 5ecmA-4q3mA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4q3m MGS-M4
(unidentified) 		4 / 6 THR A  44
ALA A  45
THR A  72
TYR A 103
 None
 0.95A 5ecoA-4q3mA:
1.7		 5ecoA-4q3mA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4q3m MGS-M4
(unidentified) 		5 / 12 GLY A  96
GLY A  55
LEU A 124
ASN A  94
PHE A  88
 None
 0.89A 5ybbA-4q3mA:
undetectable		 5ybbA-4q3mA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 4q3m MGS-M4
(unidentified) 		4 / 5 TYR A 184
GLN A 158
GLY A 262
ILE A 265
 None
 1.40A 6debB-4q3mA:
undetectable		 6debB-4q3mA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4q3m MGS-M4
(unidentified) 		5 / 11 GLY A 134
LEU A 146
ALA A 114
PHE A 121
PHE A 138
 None
 1.40A 6qgbA-4q3mA:
undetectable		 6qgbA-4q3mA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4q3m MGS-M4
(unidentified) 		5 / 10 GLY A 134
LEU A 146
ALA A 114
PHE A 121
PHE A 138
 None
 1.40A 6qgbB-4q3mA:
undetectable		 6qgbB-4q3mA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4q3m MGS-M4
(unidentified) 		5 / 10 GLY A 134
LEU A 146
ALA A 114
PHE A 121
PHE A 138
 None
 1.40A 6qgbD-4q3mA:
undetectable		 6qgbD-4q3mA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 4q3m MGS-M4
(unidentified) 		5 / 10 GLY A 134
LEU A 146
ALA A 114
PHE A 121
PHE A 138
 None
 1.39A 6qgbF-4q3mA:
undetectable		 6qgbF-4q3mA:
17.95