SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q4j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 4q4j ABC TRANSPORTER
(Thermotoga
maritima) 		4 / 8 GLN A 122
LEU A 126
LEU A   4
LEU A  92
 None
 1.09A 1hk2A-4q4jA:
undetectable		 1hk2A-4q4jA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 4q4j ABC TRANSPORTER
(Thermotoga
maritima) 		4 / 7 VAL A 490
THR A 520
THR A 516
LYS A 487
 None
 1.09A 2kotA-4q4jA:
undetectable		 2kotA-4q4jA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4q4j ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 12 GLU A 553
GLY A 549
PHE A 354
ILE A 537
GLY A 547
 None
 1.29A 3ps9A-4q4jA:
undetectable		 3ps9A-4q4jA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 4q4j ABC TRANSPORTER
(Thermotoga
maritima) 		4 / 5 ASP A 396
GLU A 335
GLY A 388
ASP A 384
 None
 1.39A 3w9tD-4q4jA:
undetectable		 3w9tD-4q4jA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EVR_A_BEZA401_0
(PUTATIVE ABC
TRANSPORTER SUBUNIT,
SUBSTRATE-BINDING
COMPONENT)		 4q4j ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 11 LEU A 162
VAL A 158
SER A 156
TYR A 275
ALA A 148
 None
 1.44A 4evrA-4q4jA:
undetectable		 4evrA-4q4jA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 4q4j ABC TRANSPORTER
(Thermotoga
maritima) 		4 / 4 LEU A 126
SER A 300
LEU A   4
LEU A 130
 None
 0.87A 4n09A-4q4jA:
undetectable		 4n09A-4q4jA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 4q4j ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 9 ILE A 272
MET A 267
VAL A 254
TYR A 278
ILE A 151
 None
 1.21A 5mzrD-4q4jA:
2.7		 5mzrD-4q4jA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 4q4j ABC TRANSPORTER
(Thermotoga
maritima) 		5 / 12 LEU A 159
LEU A 162
ILE A 163
ILE A 166
PHE A 243
 None
 0.70A 5uanB-4q4jA:
undetectable		 5uanB-4q4jA:
21.12