SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q4l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 4q4l ATP SYNTHASE SUBUNIT
BETA 1
(Burkholderia
thailandensis) 		3 / 3 GLN A 296
TYR A 262
ARG A 263
 None
 0.86A 1gtbA-4q4lA:
undetectable		 1gtbA-4q4lA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 4q4l ATP SYNTHASE SUBUNIT
BETA 1
(Burkholderia
thailandensis) 		3 / 3 SER A 125
ARG A 124
GLN A 128
 None
 0.71A 2xnrA-4q4lA:
undetectable		 2xnrA-4q4lA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 4q4l ATP SYNTHASE SUBUNIT
BETA 1
(Burkholderia
thailandensis) 		4 / 7 ASP A 449
VAL A 377
ARG A 376
ILE A 373
 None
 1.10A 2yfbA-4q4lA:
undetectable		 2yfbA-4q4lA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 4q4l ATP SYNTHASE SUBUNIT
BETA 1
(Burkholderia
thailandensis) 		4 / 4 GLU A 178
GLY A 146
THR A 145
GLU A 144
 None
 1.05A 3e9xA-4q4lA:
undetectable		 3e9xA-4q4lA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 4q4l ATP SYNTHASE SUBUNIT
BETA 1
(Burkholderia
thailandensis) 		4 / 8 VAL A 192
VAL A  96
ILE A 299
GLY A 240
 None
 0.94A 3hjoA-4q4lA:
undetectable		 3hjoA-4q4lA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4q4l ATP SYNTHASE SUBUNIT
BETA 1
(Burkholderia
thailandensis) 		4 / 5 PRO A 353
ASP A 352
ILE A 347
VAL A 170
 None
 1.28A 4hytA-4q4lA:
undetectable		 4hytA-4q4lA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4q4l ATP SYNTHASE SUBUNIT
BETA 1
(Burkholderia
thailandensis) 		4 / 7 VAL A 192
PHE A 247
HIS A 246
GLU A 245
 None
 1.19A 5ad9A-4q4lA:
undetectable
5ad9B-4q4lA:
undetectable		 5ad9A-4q4lA:
21.50
5ad9B-4q4lA:
21.50