SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 4q51 UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		5 / 9 GLY A  49
PRO A 260
GLY A 280
GLY A 287
ASP A 285
 None
 0.75A 1mxdA-4q51A:
undetectable		 1mxdA-4q51A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 4q51 UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		5 / 11 GLY A  49
PRO A 260
GLY A 280
GLY A 287
ASP A 285
 None
 0.76A 1mxgA-4q51A:
undetectable		 1mxgA-4q51A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 4q51 UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		5 / 10 PHE A 118
TYR A 206
TYR A 204
VAL A 253
LEU A 251
 None
 1.39A 2w98A-4q51A:
undetectable		 2w98A-4q51A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 4q51 UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 HIS A  85
LEU A  92
VAL A 264
ASP A 123
GLN A  93
 None
 1.12A 5hg0B-4q51A:
undetectable		 5hg0B-4q51A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_ACTA405_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 4q51 UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		3 / 3 GLN A 293
THR A 110
ASP A 275
 None
 0.79A 5k9dA-4q51A:
undetectable		 5k9dA-4q51A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 4q51 UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 ILE A  46
LEU A  51
TRP A 224
GLY A 229
TYR A 212
 None
None
CA  A 401 ( 4.9A)
None
None
 1.24A 5nnaA-4q51A:
undetectable		 5nnaA-4q51A:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 4q51 UNCHARACTERIZED
PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 ILE A  46
LEU A  51
TRP A 224
GLY A 229
TYR A 212
 None
None
CA  A 401 ( 4.9A)
None
None
 1.22A 5nnaB-4q51A:
undetectable		 5nnaB-4q51A:
26.84