SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q5g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA4_A_ACTA544_0 (ACETYLCHOLINESTERASE)	4q5g	SERUM AMYLOID A-3 PROTEIN (Mus musculus)	5 / 8	GLY A 69 GLY A 68 ALA A 72 ALA A 28 PHE A 24	None	1.28A	2ha4A-4q5gA: undetectable	2ha4A-4q5gA: 13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA4_B_ACTB601_0 (ACETYLCHOLINESTERASE)	4q5g	SERUM AMYLOID A-3 PROTEIN (Mus musculus)	5 / 7	GLY A 69 GLY A 68 ALA A 72 ALA A 28 PHE A 24	None	1.26A	2ha4B-4q5gA: undetectable	2ha4B-4q5gA: 13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_C_DXCC1476_0 (MJ0495-LIKE PROTEIN)	4q5g	SERUM AMYLOID A-3 PROTEIN (Mus musculus)	4 / 5	ILE A 76 ALA A 62 MET A 35 ARG A 33	None	1.32A	4ac9B-4q5gA: undetectable 4ac9C-4q5gA: undetectable	4ac9B-4q5gA: 11.72 4ac9C-4q5gA: 11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ACA_C_DXCC1476_0 (TRANSLATION ELONGATION FACTOR SELB)	4q5g	SERUM AMYLOID A-3 PROTEIN (Mus musculus)	4 / 5	ILE A 76 ALA A 62 MET A 35 ARG A 33	None	1.33A	4acaB-4q5gA: undetectable 4acaC-4q5gA: undetectable	4acaB-4q5gA: 11.72 4acaC-4q5gA: 11.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2HA4_A_ACTA544_0","ACETYLCHOLINESTERASE","4q5g","SERUM AMYLOID A-3 PROTEIN","Mus musculus",5,"GLY A  69;GLY A  68;ALA A  72;ALA A  28;PHE A  24","None","1.28A","2ha4A-4q5gA:undetectable","2ha4A-4q5gA:13.08"],["2HA4_B_ACTB601_0","ACETYLCHOLINESTERASE","4q5g","SERUM AMYLOID A-3 PROTEIN","Mus musculus",5,"GLY A  69;GLY A  68;ALA A  72;ALA A  28;PHE A  24","None","1.26A","2ha4B-4q5gA:undetectable","2ha4B-4q5gA:13.08"],["4AC9_C_DXCC1476_0","MJ0495-LIKE PROTEIN","4q5g","SERUM AMYLOID A-3 PROTEIN","Mus musculus",4,"ILE A  76;ALA A  62;MET A  35;ARG A  33","None","1.32A","4ac9B-4q5gA:undetectable;4ac9C-4q5gA:undetectable","4ac9B-4q5gA:11.72;4ac9C-4q5gA:11.72"],["4ACA_C_DXCC1476_0","TRANSLATION ELONGATION FACTOR SELB","4q5g","SERUM AMYLOID A-3 PROTEIN","Mus musculus",4,"ILE A  76;ALA A  62;MET A  35;ARG A  33","None","1.33A","4acaB-4q5gA:undetectable;4acaC-4q5gA:undetectable","4acaB-4q5gA:11.72;4acaC-4q5gA:11.72"]]