SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		4 / 7 TYR A   8
GLY A  13
ILE A 113
TYR A 117
 None
 0.77A 11gsB-4q5qA:
25.8		 11gsB-4q5qA:
30.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		4 / 6 ARG A  19
ALA A  15
ILE A  77
PRO A  62
 None
 1.23A 1oniB-4q5qA:
undetectable
1oniC-4q5qA:
undetectable		 1oniB-4q5qA:
22.03
1oniC-4q5qA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		5 / 11 MET A 108
LEU A 129
LEU A 132
LEU A 136
THR A 105
 None
 1.18A 2qd3A-4q5qA:
undetectable		 2qd3A-4q5qA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		5 / 12 GLY A  89
GLY A  82
LEU A 192
MET A 189
ALA A 147
 None
 1.09A 3t7vA-4q5qA:
undetectable		 3t7vA-4q5qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		5 / 12 MET A 108
LEU A 129
LEU A 132
LEU A 136
THR A 105
 None
 1.15A 4f4dA-4q5qA:
undetectable		 4f4dA-4q5qA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		4 / 5 LEU A  20
ILE A 199
LYS A 201
GLN A 202
 None
 1.10A 4ma8C-4q5qA:
undetectable		 4ma8C-4q5qA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		4 / 6 GLU A 102
ALA A  76
LEU A  78
TYR A 156
 None
 1.16A 5phhA-4q5qA:
undetectable		 5phhA-4q5qA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		3 / 3 TYR A 162
ALA A 219
TYR A 218
 None
 0.85A 5uunB-4q5qA:
15.5		 5uunB-4q5qA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4q5q GLUTATHIONE
S-TRANSFERASE
(Dermatophagoides
pteronyssinus) 		5 / 12 LEU A  54
ILE A  65
GLN A   3
TYR A  85
LEU A  81
 None
 1.21A 5y2tB-4q5qA:
undetectable		 5y2tB-4q5qA:
undetectable