SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q68'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 12 GLY A  26
VAL A 226
ILE A  34
VAL A  67
ILE A 215
 None
 1.02A 1hsgB-4q68A:
undetectable		 1hsgB-4q68A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 12 GLY A  26
VAL A 226
ILE A  34
VAL A  67
ILE A 215
 None
 1.00A 1sdtB-4q68A:
undetectable		 1sdtB-4q68A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 5 VAL A  70
TYR A  69
VAL A  61
ASP A  62
 None
None
None
NAG  A 301 (-3.1A)
 0.91A 2x45A-4q68A:
undetectable		 2x45A-4q68A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 11 ILE A 117
LEU A  71
ASN A  92
LEU A 258
ILE A 198
 None
 1.40A 3a50B-4q68A:
undetectable		 3a50B-4q68A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 12 VAL A  61
THR A  65
ILE A  96
ALA A  72
THR A  76
 None
NAG  A 301 ( 4.8A)
None
None
None
 1.25A 3ddyA-4q68A:
0.7		 3ddyA-4q68A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 12 HIS A 212
ILE A 199
LEU A 190
LEU A 246
GLY A 254
 None
 1.17A 4foxB-4q68A:
undetectable		 4foxB-4q68A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		5 / 12 ASP A 197
VAL A 257
GLY A 196
ASP A 195
GLY A 189
 None
 1.09A 4pevB-4q68A:
undetectable		 4pevB-4q68A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		3 / 3 ASN A 118
ALA A 114
ARG A 256
 None
 0.47A 5cvtB-4q68A:
undetectable		 5cvtB-4q68A:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 8 GLY A 189
TRP A 192
ASP A 197
ARG A 259
 None
 0.88A 5gqbA-4q68A:
undetectable		 5gqbA-4q68A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 4q68 UNCHARACTERIZED
PROTEIN
(Bacteroides
uniformis) 		4 / 6 GLY A 120
ASN A 119
ILE A 198
TRP A 116
 None
 1.03A 5j4nA-4q68A:
undetectable		 5j4nA-4q68A:
18.66