SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q69'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 10 ALA A 180
ASN A 125
ALA A 128
GLN A 129
ILE A 132
 None
 0.92A 1likA-4q69A:
undetectable		 1likA-4q69A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A  75
LEU A  77
VAL A 328
LEU A 310
ASP A  78
 None
 1.14A 2f8lA-4q69A:
undetectable		 2f8lA-4q69A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A  83
ARG A 313
ILE A  63
SER A  93
 None
 1.31A 3ckzA-4q69A:
undetectable		 3ckzA-4q69A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A  84
GLY A  59
LEU A  65
SER A  90
SER A  93
 None
 1.03A 3g2oA-4q69A:
undetectable		 3g2oA-4q69A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A  84
GLY A  59
LEU A  65
SER A  90
SER A  93
 None
 0.97A 3g2oB-4q69A:
undetectable		 3g2oB-4q69A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 GLU A 354
TYR A 343
GLN A 431
LEU A 421
 None
 1.01A 3qeoB-4q69A:
2.3		 3qeoB-4q69A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A 335
PRO A 425
SER A  66
MET A 422
 GOL  A 503 (-3.4A)
None
None
None
 1.35A 4kmmA-4q69A:
undetectable		 4kmmA-4q69A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 9 TYR A 101
VAL A 173
HIS A 100
TRP A  52
LEU A 109
 None
 1.35A 4l1xB-4q69A:
undetectable		 4l1xB-4q69A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 11 MET A 203
LEU A 209
ALA A 210
LEU A 177
ILE A 127
 None
 1.21A 4pxmB-4q69A:
undetectable		 4pxmB-4q69A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ALA A 316
PRO A 315
GLY A  80
GLY A  75
LEU A  77
 None
 1.11A 5c0oE-4q69A:
undetectable		 5c0oE-4q69A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCM_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A  56
GLY A  54
ASN A  51
ASN A 259
TYR A 198
 None
 1.29A 5ccmA-4q69A:
5.3		 5ccmA-4q69A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCM_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A  56
GLY A  54
ASN A 259
ASN A  46
TYR A 198
 None
 1.06A 5ccmA-4q69A:
5.3		 5ccmA-4q69A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NR3_A_95EA401_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 3B)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 7 ILE A 457
ASP A 487
LYS A 483
SER A 435
 None
NA  A 501 (-3.1A)
None
None
 1.18A 5nr3A-4q69A:
undetectable		 5nr3A-4q69A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 239
GLU A 352
LEU A 349
LEU A 350
LEU A 372
 None
 0.98A 5nwwA-4q69A:
undetectable		 5nwwA-4q69A:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TQR_B_SAMB8009_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2, POLYCOMB
PROTEIN SUZ12)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 10 LEU A 109
TYR A  43
VAL A  50
TYR A 195
TYR A 198
 None
 1.39A 5tqrB-4q69A:
undetectable		 5tqrB-4q69A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXG_A_SAMA502_0
(SMYD3)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A  56
GLY A  54
ASN A  51
ASN A 259
TYR A 198
 None
 1.17A 5xxgA-4q69A:
5.4		 5xxgA-4q69A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXG_A_SAMA502_0
(SMYD3)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 12 ARG A  56
GLY A  54
ASN A 259
ASN A  46
TYR A 198
 None
 0.93A 5xxgA-4q69A:
5.4		 5xxgA-4q69A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		5 / 10 MET A 203
LEU A 209
ALA A 210
LEU A 177
ILE A 127
 None
 1.21A 6cbzB-4q69A:
undetectable		 6cbzB-4q69A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_F_LLLF301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4q69 PUTATIVE LIPOPROTEIN
(Bacteroides
thetaiotaomicron) 		4 / 5 ASP A 292
TYR A 298
ASP A 420
CYH A 345
 None
 1.43A 6mn5F-4q69A:
0.0		 6mn5F-4q69A:
12.41