SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q6l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 4q6l PENICILLIN-BINDING
PROTEIN ACTIVATOR
LPOB
(Salmonella
enterica) 		5 / 12 ILE A 202
TYR A 174
LEU A 102
PHE A 134
LEU A 128
 None
 1.30A 2mjiA-4q6lA:
1.7		 2mjiA-4q6lA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 4q6l PENICILLIN-BINDING
PROTEIN ACTIVATOR
LPOB
(Salmonella
enterica) 		5 / 9 VAL A  87
MET A 191
LEU A 193
VAL A 104
LEU A 124
 None
 1.06A 5lw1H-4q6lA:
undetectable		 5lw1H-4q6lA:
23.48