SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBK_A_RAPA225_1
(FKBP25)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		5 / 12 LEU A 427
GLY A 416
VAL A 414
ILE A 355
ILE A 397
 None
 0.95A 1pbkA-4q7lA:
undetectable		 1pbkA-4q7lA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 6 ASP A 418
LEU A 413
VAL A 414
ILE A 355
 None
 0.99A 1s9qA-4q7lA:
undetectable		 1s9qA-4q7lA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 8 PHE A 473
THR A 503
LEU A 449
VAL A 445
 None
 1.19A 1uyuA-4q7lA:
undetectable		 1uyuA-4q7lA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 8 PHE A 473
THR A 503
LEU A 449
VAL A 445
 None
 1.17A 1uyuB-4q7lA:
undetectable		 1uyuB-4q7lA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 4 GLY A 388
SER A 392
VAL A 568
LEU A 586
 None
 1.03A 1yajB-4q7lA:
undetectable		 1yajB-4q7lA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		5 / 12 ILE A 412
ILE A 419
ARG A 428
ILE A 544
PHE A 357
 None
 1.11A 2ygnA-4q7lA:
undetectable		 2ygnA-4q7lA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		5 / 12 ILE A 412
ILE A 419
ARG A 428
ILE A 544
VAL A 370
 None
 1.15A 2ygnA-4q7lA:
undetectable		 2ygnA-4q7lA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		5 / 9 ILE A 560
LEU A 386
ILE A 545
MET A 534
ILE A 514
 None
 1.05A 3zosA-4q7lA:
undetectable		 3zosA-4q7lA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 8 PHE A 473
THR A 503
LEU A 449
VAL A 445
 None
 1.07A 4l4dA-4q7lA:
undetectable		 4l4dA-4q7lA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 8 PHE A 473
THR A 503
LEU A 449
VAL A 445
 None
 1.13A 4l4eA-4q7lA:
undetectable		 4l4eA-4q7lA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 8 PHE A 473
THR A 503
LEU A 449
VAL A 445
 None
 1.15A 4l4fA-4q7lA:
undetectable		 4l4fA-4q7lA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		5 / 9 ILE A 422
LEU A 513
VAL A 398
LEU A 401
ILE A 544
 None
 1.21A 4r38C-4q7lA:
undetectable		 4r38C-4q7lA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 5 GLN A 531
HIS A 469
ILE A 530
ILE A 502
 None
 1.20A 5dnvA-4q7lA:
undetectable		 5dnvA-4q7lA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 4q7l UNCHARACTERIZED ABC
TRANSPORTER
ATP-BINDING PROTEIN
TM_0288
(Thermotoga
maritima) 		4 / 6 PHE A 506
SER A 470
LEU A 449
LEU A 507
 None
 1.08A 5dzke-4q7lA:
2.1
5dzks-4q7lA:
undetectable		 5dzke-4q7lA:
22.51
5dzks-4q7lA:
1.33