SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 4q7o IMMUNITY PROTEIN
(Neisseria
meningitidis) 		5 / 11 PHE A  24
ILE A  84
PHE A  86
PHE A 108
LEU A  37
 None
 1.23A 3a9eB-4q7oA:
undetectable		 3a9eB-4q7oA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4q7o IMMUNITY PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  28
GLU A  32
ILE A 112
LEU A  38
 None
 0.67A 4mj8A-4q7oA:
undetectable		 4mj8A-4q7oA:
27.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 4q7o IMMUNITY PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  28
PHE A  24
THR A  46
THR A  47
 None
 0.82A 4n16A-4q7oA:
undetectable		 4n16A-4q7oA:
21.70