SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_A_PAUA6001_0
(PANTOTHENATE KINASE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		5 / 9 ASP A 251
LEU A 253
LEU A  34
ILE A 263
ASN A 260
 None
 1.48A 1sq5A-4q7qA:
0.9		 1sq5A-4q7qA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_B_PAUB6003_0
(PANTOTHENATE KINASE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		5 / 10 ASP A 251
LEU A 253
LEU A  34
ILE A 263
ASN A 260
 None
 1.47A 1sq5B-4q7qA:
undetectable		 1sq5B-4q7qA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_C_PAUC6002_0
(PANTOTHENATE KINASE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		5 / 9 ASP A 251
LEU A 253
LEU A  34
ILE A 263
ASN A 260
 None
 1.48A 1sq5C-4q7qA:
0.8		 1sq5C-4q7qA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		5 / 10 ASP A 251
LEU A 253
LEU A  34
ILE A 263
ASN A 260
 None
 1.46A 1sq5D-4q7qA:
undetectable		 1sq5D-4q7qA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		5 / 11 ASP A 156
GLY A  69
SER A  30
PHE A 151
HIS A 254
 None
PG4  A 301 ( 3.7A)
PG4  A 301 ( 4.4A)
PG4  A 301 (-4.6A)
None
 1.40A 1w76A-4q7qA:
2.2		 1w76A-4q7qA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		4 / 7 TYR A  62
GLY A  48
THR A  51
ASN A 260
 None
 0.91A 2g70A-4q7qA:
4.5		 2g70A-4q7qA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		4 / 7 TYR A  62
GLY A  48
THR A  51
ASN A 260
 None
 0.94A 2g70B-4q7qA:
undetectable		 2g70B-4q7qA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		4 / 8 ARG A  52
ALA A 264
ILE A 263
PRO A 255
 None
 0.66A 3fxrA-4q7qA:
undetectable		 3fxrA-4q7qA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		4 / 7 ILE A  31
ILE A 143
SER A 256
LEU A 200
 None
 0.69A 3ua5B-4q7qA:
undetectable		 3ua5B-4q7qA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		3 / 3 TRP A 100
TRP A  99
THR A  96
 None
 1.47A 4bboB-4q7qA:
undetectable		 4bboB-4q7qA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		4 / 8 ASN A  97
TRP A 100
ASN A 169
TRP A  99
 PG4  A 301 ( 4.3A)
None
None
None
 1.26A 4d1yA-4q7qA:
4.1
4d1yB-4q7qA:
3.7		 4d1yA-4q7qA:
21.30
4d1yB-4q7qA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		4 / 8 ASN A 169
TRP A  99
ASN A  97
TRP A 100
 None
None
PG4  A 301 ( 4.3A)
None
 1.27A 4d1yA-4q7qA:
4.1
4d1yB-4q7qA:
3.7		 4d1yA-4q7qA:
21.30
4d1yB-4q7qA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		5 / 10 GLY A  73
GLY A 122
SER A 123
ARG A 125
ILE A 127
 None
 1.02A 5aqfA-4q7qA:
undetectable		 5aqfA-4q7qA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		5 / 10 GLY A  73
GLY A 122
SER A 123
ARG A 125
ILE A 127
 None
 1.01A 5aqfC-4q7qA:
undetectable		 5aqfC-4q7qA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		5 / 12 TYR A 241
ILE A 154
TYR A 239
PHE A 227
THR A 201
 None
 1.30A 5eslA-4q7qA:
undetectable		 5eslA-4q7qA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 4q7q LIPOLYTIC PROTEIN
G-D-S-L FAMILY
(Chitinophaga
pinensis) 		3 / 3 ALA A 179
PHE A 176
GLN A 171
 None
 0.76A 6eceA-4q7qA:
4.4		 6eceA-4q7qA:
22.68