SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q88'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 TRP A 153
PHE A 233
ILE A 192
LEU A 159
ALA A 229
 None
 1.34A 1jb0B-4q88A:
undetectable		 1jb0B-4q88A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 LEU A  31
ALA A 365
VAL A  37
ILE A 358
GLY A  61
 None
 1.05A 1k6cA-4q88A:
undetectable		 1k6cA-4q88A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TRP A 271
TYR A 270
LEU A 321
 None
 1.04A 1kxhA-4q88A:
undetectable		 1kxhA-4q88A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_B_DVAB8_0
(GRAMICIDIN A)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 VAL A 116
TRP A 153
TRP A 228
VAL A 162
 None
 1.40A 1micA-4q88A:
undetectable
1micB-4q88A:
undetectable		 1micA-4q88A:
4.68
1micB-4q88A:
4.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 ALA A 360
PHE A 361
ALA A 365
ARG A 368
 None
 0.69A 2bxmA-4q88A:
undetectable		 2bxmA-4q88A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 10 ALA A 360
PHE A 361
ALA A 365
ARG A 368
LEU A  30
 None
 1.11A 2bxqA-4q88A:
undetectable		 2bxqA-4q88A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 TYR A 320
GLU A 285
PHE A 356
GLY A 288
 None
 1.04A 2ha4A-4q88A:
undetectable		 2ha4A-4q88A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 LEU A 362
ALA A 364
TRP A 318
LEU A 321
 None
 1.23A 2oaxA-4q88A:
undetectable		 2oaxA-4q88A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 LEU A 305
ALA A 262
ILE A 261
SER A 260
 None
 1.11A 2othA-4q88A:
undetectable		 2othA-4q88A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLY A 357
GLY A 359
ALA A 364
ASP A  54
VAL A 338
 None
 1.08A 2zulA-4q88A:
undetectable		 2zulA-4q88A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLY A 357
GLY A 359
ALA A 364
ASP A  54
VAL A 338
 None
 1.10A 3dmfA-4q88A:
undetectable		 3dmfA-4q88A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLY A 357
GLY A 359
ALA A 364
ASP A  54
VAL A 338
 None
 1.08A 3dmhA-4q88A:
undetectable		 3dmhA-4q88A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 MET A 161
MET A  63
PHE A 356
 None
 1.18A 3gn8A-4q88A:
undetectable		 3gn8A-4q88A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_2
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 THR A 120
ASN A  85
TRP A  81
TRP A 228
 None
 1.29A 3jzjA-4q88A:
0.0		 3jzjA-4q88A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 9 ARG A 253
LEU A 305
PHE A 296
LEU A 159
GLY A 295
 None
 1.14A 3nxuB-4q88A:
undetectable		 3nxuB-4q88A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 TRP A 153
PHE A 233
ILE A 192
LEU A 159
ALA A 229
 None
 1.34A 3pcqB-4q88A:
undetectable		 3pcqB-4q88A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 TYR A 320
THR A 293
ILE A 358
VAL A  37
ILE A  34
 None
 1.39A 4eb6B-4q88A:
undetectable
4eb6C-4q88A:
undetectable		 4eb6B-4q88A:
23.28
4eb6C-4q88A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 PHE A 221
TYR A 202
PRO A 210
TYR A 209
 None
 1.31A 4grqA-4q88A:
undetectable
4grqC-4q88A:
undetectable		 4grqA-4q88A:
15.32
4grqC-4q88A:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_1
(SERINE/THREONINE-PRO
TEIN PHOSPHATASE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 TRP A  81
SER A  51
PHE A  52
GLU A 104
 None
 1.23A 5b8iA-4q88A:
undetectable		 5b8iA-4q88A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 CYH A 353
ILE A 358
HIS A  45
TYR A  41
 None
 1.33A 5ocsA-4q88A:
undetectable		 5ocsA-4q88A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_C_ACTC402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 CYH A 353
ILE A 358
HIS A  45
TYR A  41
 None
 1.32A 5ocsC-4q88A:
undetectable		 5ocsC-4q88A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 ILE A  33
ARG A  36
GLN A  39
TYR A  74
 None
 0.88A 5vlmF-4q88A:
undetectable		 5vlmF-4q88A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 4q88 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TYR A  84
ASP A  80
GLN A  48
 None
 0.96A 6g1pA-4q88A:
undetectable		 6g1pA-4q88A:
20.98