SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4004_1
(SERUM ALBUMIN)		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		4 / 4 VAL A 125
PHE A  51
SER A 127
VAL A 171
 None
 1.46A 1e7cA-4q9aA:
undetectable		 1e7cA-4q9aA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		5 / 12 CYH A  47
THR A  82
PHE A  51
PHE A  74
LEU A  43
 None
 1.49A 3u9fJ-4q9aA:
undetectable
3u9fL-4q9aA:
undetectable		 3u9fJ-4q9aA:
20.08
3u9fL-4q9aA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		4 / 7 PHE A 214
TYR A  78
TRP A 249
PHE A  51
 None
 1.39A 4grqA-4q9aA:
undetectable
4grqC-4q9aA:
undetectable		 4grqA-4q9aA:
18.78
4grqC-4q9aA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		5 / 12 VAL A 132
ASP A 233
ILE A 184
GLY A 181
VAL A 222
 None
 0.97A 4y8wA-4q9aA:
undetectable		 4y8wA-4q9aA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		5 / 12 VAL A 132
ASP A 233
ILE A 184
GLY A 181
VAL A 222
 None
 0.96A 4y8wB-4q9aA:
undetectable		 4y8wB-4q9aA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		4 / 5 GLY A 181
ASP A 180
ARG A 179
MET A 248
 None
 1.12A 5zrfB-4q9aA:
3.4		 5zrfB-4q9aA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		4 / 4 GLY A 181
ASP A 180
ARG A 179
MET A 248
 None
 1.08A 5zrfA-4q9aA:
3.0		 5zrfA-4q9aA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		4 / 6 GLY A 145
THR A 149
TYR A 108
TYR A 143
 None
 1.16A 6ag0C-4q9aA:
undetectable		 6ag0C-4q9aA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 4q9a TAT PATHWAY SIGNAL
SEQUENCE DOMAIN
PROTEIN
(Parabacteroides
merdae) 		4 / 7 SER A  76
GLY A  60
ARG A 242
LEU A 239
 None
 1.13A 6btxA-4q9aA:
undetectable		 6btxA-4q9aA:
18.83