SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q9b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AV2_D_DVAD6_0 (GRAMICIDIN A)	4q9b	NOVEL ANTIGEN RECEPTOR (Ginglymostoma cirratum)	3 / 3	TRP A 258 ALA A 263 VAL A 254	None	0.98A	1av2C-4q9bA: undetectable 1av2D-4q9bA: undetectable	1av2C-4q9bA: 10.39 1av2D-4q9bA: 10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q6I_B_FK5B401_1 (FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA)	4q9b	NOVEL ANTIGEN RECEPTOR (Ginglymostoma cirratum)	5 / 10	TYR A 323 ARG A 288 LEU A 310 ILE A 257 TRP A 317	None	1.16A	1q6iB-4q9bA: undetectable	1q6iB-4q9bA: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_B_DVAB6_0 (GRAMICIDIN D)	4q9b	NOVEL ANTIGEN RECEPTOR (Ginglymostoma cirratum)	3 / 3	TRP A 258 ALA A 263 VAL A 254	None	0.97A	1w5uA-4q9bA: undetectable 1w5uB-4q9bA: undetectable	1w5uA-4q9bA: 10.39 1w5uB-4q9bA: 10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FWD_A_BO2A801_1 (TTC1975 PEPTIDASE)	4q9b	NOVEL ANTIGEN RECEPTOR (Ginglymostoma cirratum)	5 / 9	VAL A 277 VAL A 278 VAL A 247 ILE A 245 ALA A 275	None	1.20A	4fwdA-4q9bA: undetectable	4fwdA-4q9bA: 9.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AV2_D_DVAD6_0","GRAMICIDIN A","4q9b","NOVEL ANTIGEN RECEPTOR","Ginglymostoma cirratum",3,"TRP A 258;ALA A 263;VAL A 254","None","0.98A","1av2C-4q9bA:undetectable;1av2D-4q9bA:undetectable","1av2C-4q9bA:10.39;1av2D-4q9bA:10.39"],["1Q6I_B_FK5B401_1","FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA","4q9b","NOVEL ANTIGEN RECEPTOR","Ginglymostoma cirratum",5,"TYR A 323;ARG A 288;LEU A 310;ILE A 257;TRP A 317","None","1.16A","1q6iB-4q9bA:undetectable","1q6iB-4q9bA:16.96"],["1W5U_B_DVAB6_0","GRAMICIDIN D","4q9b","NOVEL ANTIGEN RECEPTOR","Ginglymostoma cirratum",3,"TRP A 258;ALA A 263;VAL A 254","None","0.97A","1w5uA-4q9bA:undetectable;1w5uB-4q9bA:undetectable","1w5uA-4q9bA:10.39;1w5uB-4q9bA:10.39"],["4FWD_A_BO2A801_1","TTC1975 PEPTIDASE","4q9b","NOVEL ANTIGEN RECEPTOR","Ginglymostoma cirratum",5,"VAL A 277;VAL A 278;VAL A 247;ILE A 245;ALA A 275","None","1.20A","4fwdA-4q9bA:undetectable","4fwdA-4q9bA:9.71"]]