SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 4q9c NOVEL ANTIGEN
RECEPTOR
(Ginglymostoma
cirratum) 		5 / 11 LEU A 418
ILE A 362
SER A 358
PRO A 357
THR A 371
 None
None
None
NA  A 905 (-4.2A)
NA  A 905 (-3.6A)
 1.16A 3bjwB-4q9cA:
undetectable		 3bjwB-4q9cA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 4q9c NOVEL ANTIGEN
RECEPTOR
(Ginglymostoma
cirratum) 		5 / 11 LEU A 418
ILE A 362
SER A 358
PRO A 357
THR A 371
 None
None
None
NA  A 905 (-4.2A)
NA  A 905 (-3.6A)
 1.18A 3bjwH-4q9cA:
undetectable		 3bjwH-4q9cA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 4q9c NOVEL ANTIGEN
RECEPTOR
(Ginglymostoma
cirratum) 		3 / 3 ASN A 448
TRP A 423
ASP A 389
 None
 1.16A 4a7tA-4q9cA:
3.8
4a7tF-4q9cA:
3.9		 4a7tA-4q9cA:
19.25
4a7tF-4q9cA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_B_IMNB201_1
(TRANSTHYRETIN)		 4q9c NOVEL ANTIGEN
RECEPTOR
(Ginglymostoma
cirratum) 		4 / 6 LEU A 370
ALA A 368
LEU A 416
THR A 419
 None
 1.02A 4ikiB-4q9cA:
undetectable		 4ikiB-4q9cA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 4q9c NOVEL ANTIGEN
RECEPTOR
(Ginglymostoma
cirratum) 		4 / 6 LEU A 370
ALA A 368
LEU A 416
THR A 419
 None
 1.01A 5l4iA-4q9cA:
undetectable		 5l4iA-4q9cA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 4q9c NOVEL ANTIGEN
RECEPTOR
(Ginglymostoma
cirratum) 		4 / 6 ARG A 375
GLY A 376
THR A 409
GLU A 405
 CL  A 903 (-4.1A)
PG4  A 902 ( 4.1A)
PG4  A 902 ( 4.7A)
PG4  A 902 (-4.5A)
 1.11A 5ny7A-4q9cA:
undetectable		 5ny7A-4q9cA:
14.89