SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4q9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.97A 1t85A-4q9oA:
undetectable
1t85A-4q9oA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
1.04A 1t87A-4q9oA:
undetectable
1t87A-4q9oA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.95A 1yrcA-4q9oA:
undetectable
1yrcA-4q9oA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.97A 1yrdA-4q9oA:
undetectable
1yrdA-4q9oA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 6 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.88A 2feuA-4q9oA:
undetectable
2feuA-4q9oA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.95A 2feuB-4q9oA:
undetectable
2feuB-4q9oA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 6 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
1.02A 2zuhA-4q9oA:
undetectable
2zuhA-4q9oA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 6 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.99A 2zuiA-4q9oA:
undetectable
2zuiA-4q9oA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.96A 2zwtA-4q9oA:
undetectable
2zwtA-4q9oA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.95A 2zwuA-4q9oA:
undetectable
2zwuA-4q9oA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.92A 3fwfA-4q9oA:
undetectable
3fwfA-4q9oA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.92A 3fwfB-4q9oA:
undetectable
3fwfB-4q9oA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.95A 3fwiA-4q9oA:
undetectable
3fwiA-4q9oA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.94A 3fwjA-4q9oA:
undetectable
3fwjA-4q9oA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
3 / 3 ASP A  28
ARG A 200
ARG A  41
None
None
SO4  A 302 (-3.7A)
0.99A 3k37A-4q9oA:
undetectable
3k37A-4q9oA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.89A 3l63A-4q9oA:
undetectable
3l63A-4q9oA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.96A 3wrhA-4q9oA:
undetectable
3wrhA-4q9oA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.95A 3wrjA-4q9oA:
undetectable
3wrjA-4q9oA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.94A 3wrlA-4q9oA:
undetectable
3wrlA-4q9oA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.95A 3wrlE-4q9oA:
undetectable
3wrlE-4q9oA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.93A 3wrmA-4q9oA:
undetectable
3wrmA-4q9oA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.95A 3wrmF-4q9oA:
undetectable
3wrmF-4q9oA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_A_LURA201_1
(TRANSTHYRETIN)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 4 LYS A  65
LEU A 192
ALA A  21
VAL A  19
None
1.48A 4ik6A-4q9oA:
undetectable
4ik6A-4q9oA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 8 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.96A 4l4aA-4q9oA:
undetectable
4l4aA-4q9oA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
1.03A 4l4gA-4q9oA:
undetectable
4l4gA-4q9oA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_C_NOVC2000_1
(DNA GYRASE SUBUNIT B)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
5 / 12 ARG A 193
ILE A 179
GLN A 155
ALA A 156
ILE A 160
None
1.19A 4uroC-4q9oA:
undetectable
4uroC-4q9oA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 7 PHE A 143
THR A  56
LEU A 102
VAL A  99
2ZW  A 301 (-3.5A)
2ZW  A 301 ( 4.9A)
2ZW  A 301 (-4.5A)
2ZW  A 301 (-4.6A)
0.98A 5wk9A-4q9oA:
undetectable
5wk9A-4q9oA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae)
4 / 6 TYR A  70
VAL A  64
PHE A 184
GLY A 149
None
0.96A 6hd4B-4q9oA:
undetectable
6hd4B-4q9oA:
14.05