SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qaf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 4qaf LIPOCALIN-1
(Homo
sapiens) 		4 / 7 VAL A  67
LEU A  44
THR A  42
LEU A  41
 None
None
None
OMA  A 201 ( 4.8A)
 0.72A 1jgsA-4qafA:
undetectable		 1jgsA-4qafA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 4qaf LIPOCALIN-1
(Homo
sapiens) 		5 / 12 GLY A 112
GLY A  27
ASP A  25
TYR A  77
ILE A  80
 None
 1.06A 3prsA-4qafA:
undetectable		 3prsA-4qafA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 4qaf LIPOCALIN-1
(Homo
sapiens) 		5 / 12 TYR A 100
ILE A  80
GLY A 103
HIS A  84
ILE A  83
 None
None
None
None
OMA  A 201 ( 4.9A)
 1.13A 4rvgA-4qafA:
undetectable		 4rvgA-4qafA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 4qaf LIPOCALIN-1
(Homo
sapiens) 		5 / 10 ILE A  80
LEU A  19
VAL A  53
LEU A 115
PRO A  38
 None
 1.16A 5ienB-4qafA:
undetectable		 5ienB-4qafA:
20.38