SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qav'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 10 PHE A 410
ALA A 394
ALA A 257
LEU A  11
VAL A  21
 None
 1.34A 1claA-4qavA:
undetectable		 1claA-4qavA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 LEU A  28
GLY A  18
SER A  15
GLY A 236
LEU A 341
 None
 1.12A 1fe2A-4qavA:
undetectable		 1fe2A-4qavA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		6 / 11 GLY A 263
ALA A 286
ASP A 289
ILE A 172
VAL A 300
ILE A 395
 None
 1.33A 1ohrA-4qavA:
undetectable		 1ohrA-4qavA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 ILE A 186
GLY A  10
ILE A  86
VAL A   7
GLU A 244
 None
 1.11A 1sg9A-4qavA:
undetectable		 1sg9A-4qavA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 7 GLU A 295
ALA A 321
LYS A 288
ALA A 286
 None
 1.16A 1sn0B-4qavA:
undetectable
1sn0D-4qavA:
undetectable		 1sn0B-4qavA:
17.44
1sn0D-4qavA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 7 HIS A 170
ALA A 169
GLY A 346
GLY A 168
PHE A 262
 None
 1.50A 2c49B-4qavA:
undetectable		 2c49B-4qavA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 GLY A 190
GLY A 168
HIS A 170
ALA A 237
ALA A  82
 None
 0.91A 2gluA-4qavA:
undetectable		 2gluA-4qavA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		3 / 3 ASP A 229
ARG A 228
ARG A 222
 None
None
FMT  A 502 (-3.1A)
 0.91A 2j9dA-4qavA:
undetectable
2j9dC-4qavA:
undetectable		 2j9dA-4qavA:
13.83
2j9dC-4qavA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 ILE A 233
ALA A 192
GLY A 236
GLY A 234
VAL A  14
 None
 1.11A 2okcA-4qavA:
undetectable		 2okcA-4qavA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 ILE A 233
ALA A 192
GLY A 236
GLY A 234
VAL A  14
 None
 1.10A 2okcB-4qavA:
undetectable		 2okcB-4qavA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 9 ILE A 395
ALA A 280
VAL A 283
LYS A 288
 None
 1.00A 2vufB-4qavA:
undetectable		 2vufB-4qavA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 4 GLY A 168
GLY A 191
GLY A 107
GLY A 190
 None
 0.67A 3bogD-4qavA:
undetectable		 3bogD-4qavA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 GLU A 193
ALA A 192
GLY A 107
SER A 145
GLY A 347
 None
 1.05A 3g2oA-4qavA:
undetectable		 3g2oA-4qavA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 8 VAL A 348
GLN A  13
ILE A 141
GLY A 343
 None
 0.87A 3hjoA-4qavA:
undetectable		 3hjoA-4qavA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 GLY A 190
GLY A 168
VAL A 348
ALA A  81
ALA A  82
 None
 1.16A 3mteA-4qavA:
undetectable		 3mteA-4qavA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 ALA A 209
PHE A 231
ILE A 110
LEU A 342
GLY A 203
 None
 0.93A 3rukB-4qavA:
undetectable		 3rukB-4qavA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		3 / 3 TYR A 181
LEU A 240
ARG A 177
 None
 0.72A 3sufB-4qavA:
undetectable		 3sufB-4qavA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_A_9PLA1_1
(CYTOCHROME P450 2A13)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 9 PHE A 231
ALA A 345
PHE A 204
PHE A 401
ALA A 164
 None
 1.41A 3t3sA-4qavA:
undetectable		 3t3sA-4qavA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 ILE A 239
VAL A 148
ILE A 102
LEU A  97
VAL A  94
 None
 0.93A 3w67C-4qavA:
undetectable		 3w67C-4qavA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 GLY A 347
GLY A 346
VAL A 188
ILE A 172
PHE A 410
 None
 1.17A 4fglA-4qavA:
undetectable
4fglB-4qavA:
undetectable		 4fglA-4qavA:
21.12
4fglB-4qavA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 8 GLY A 347
VAL A 348
PHE A 410
ILE A 354
 None
 0.85A 4fglD-4qavA:
undetectable		 4fglD-4qavA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 7 GLY A 347
VAL A 348
PHE A 410
ILE A 354
 None
 0.83A 4fglC-4qavA:
undetectable		 4fglC-4qavA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		6 / 12 TYR A 352
GLY A 238
GLY A 347
LEU A  11
ASP A  88
ALA A  85
 None
 1.32A 4krhA-4qavA:
undetectable		 4krhA-4qavA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 TYR A 352
GLY A 238
GLY A 347
LEU A  11
ALA A  85
 None
 1.12A 4krhB-4qavA:
undetectable		 4krhB-4qavA:
23.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		10 / 12 GLY A 109
ALA A 164
CYH A 165
GLU A 193
PHE A 204
HIS A 303
THR A 305
HIS A 340
LEU A 342
GLY A 400
 None
 0.62A 4ls7A-4qavA:
69.6		 4ls7A-4qavA:
52.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_A_1X9A504_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		6 / 12 GLY A 109
ALA A 164
GLU A 193
PHE A 204
GLY A 400
PHE A 401
 None
 0.76A 4ls7A-4qavA:
69.6		 4ls7A-4qavA:
52.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		8 / 12 ALA A 164
CYH A 165
PHE A 204
HIS A 303
THR A 305
HIS A 340
LEU A 342
GLY A 400
 None
 0.62A 4ls7A-4qavA:
69.6
4ls7B-4qavA:
69.4		 4ls7A-4qavA:
52.33
4ls7B-4qavA:
52.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LS7_B_1X9B503_1
(3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		6 / 12 ILE A 110
ALA A 164
CYH A 165
HIS A 303
THR A 305
GLY A 400
 None
 0.79A 4ls7A-4qavA:
69.6
4ls7B-4qavA:
69.4		 4ls7A-4qavA:
52.33
4ls7B-4qavA:
52.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 9 VAL A 351
ALA A 350
TYR A 352
GLY A 236
GLY A 346
 None
 1.27A 4mm5A-4qavA:
undetectable		 4mm5A-4qavA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 11 VAL A 351
ALA A 350
TYR A 352
GLY A 236
GLY A 346
 None
 1.25A 4mm9A-4qavA:
undetectable		 4mm9A-4qavA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 9 VAL A 351
ALA A 350
TYR A 352
GLY A 236
GLY A 346
 None
 1.30A 4mmbA-4qavA:
undetectable		 4mmbA-4qavA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 10 VAL A 351
ALA A 350
TYR A 352
GLY A 236
GLY A 346
 None
 1.24A 4mmdA-4qavA:
undetectable		 4mmdA-4qavA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 9 VAL A 351
ALA A 350
TYR A 352
GLY A 236
GLY A 346
 None
 1.16A 4mmeA-4qavA:
undetectable		 4mmeA-4qavA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 9 VAL A 351
ALA A 350
TYR A 352
GLY A 236
GLY A 346
 None
 1.19A 4mmeB-4qavA:
undetectable		 4mmeB-4qavA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 9 VAL A 351
ALA A 350
TYR A 352
GLY A 236
GLY A 346
 None
 1.17A 4mmfA-4qavA:
undetectable		 4mmfA-4qavA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 9 VAL A 351
ALA A 350
TYR A 352
GLY A 236
GLY A 346
 None
 1.22A 4mmfB-4qavA:
undetectable		 4mmfB-4qavA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 6 ALA A 350
GLY A 173
ILE A 354
VAL A   6
 None
 0.75A 4r21A-4qavA:
undetectable		 4r21A-4qavA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 7 GLY A 200
MET A 207
ALA A 195
ILE A 110
 None
 0.95A 4txnA-4qavA:
undetectable		 4txnA-4qavA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 7 GLY A 200
MET A 207
ALA A 195
ILE A 110
 None
 0.94A 4txnC-4qavA:
undetectable		 4txnC-4qavA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 7 GLY A 200
MET A 207
ALA A 195
ILE A 110
 None
 0.96A 4txnD-4qavA:
undetectable		 4txnD-4qavA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 VAL A  94
GLY A 252
ALA A 253
THR A   9
VAL A 241
 None
 0.93A 4xdrA-4qavA:
undetectable		 4xdrA-4qavA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 7 CYH A 165
GLY A 406
ASN A 405
HIS A 303
 None
 1.17A 5a5zC-4qavA:
undetectable		 5a5zC-4qavA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		3 / 3 ARG A 412
ILE A 255
PHE A 413
 None
 0.62A 5kirA-4qavA:
undetectable		 5kirA-4qavA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		4 / 7 TYR A 352
ALA A  81
GLY A  78
TYR A  77
 None
 1.07A 5uxdA-4qavA:
undetectable		 5uxdA-4qavA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 12 ASP A 359
PHE A 410
ILE A 259
ALA A 189
ALA A  85
 None
 1.15A 5vcgA-4qavA:
undetectable		 5vcgA-4qavA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		5 / 10 SER A 108
GLY A 109
ILE A 196
ALA A 195
LEU A 113
 None
 1.47A 5zjiA-4qavA:
undetectable
5zjiJ-4qavA:
undetectable		 5zjiA-4qavA:
12.44
5zjiJ-4qavA:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		3 / 3 THR A 407
ALA A 286
LYS A 288
 None
 0.66A 6fgcA-4qavA:
undetectable		 6fgcA-4qavA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2
(Neisseria
meningitidis) 		3 / 3 THR A 407
ALA A 286
LYS A 288
 None
 0.68A 6fgdA-4qavA:
undetectable		 6fgdA-4qavA:
21.94