SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 4qb5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Rhodoferax
ferrireducens) 		3 / 3 CYH A  76
HIS A  80
PHE A  79
 None
 1.04A 3cr4X-4qb5A:
undetectable		 3cr4X-4qb5A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4qb5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Rhodoferax
ferrireducens) 		4 / 7 ILE A  28
PHE A  18
LYS A  16
GLY A  31
 None
 1.06A 3em0B-4qb5A:
undetectable		 3em0B-4qb5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 4qb5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Rhodoferax
ferrireducens) 		3 / 3 ARG A  98
LEU A 107
THR A  65
 None
 0.79A 3oxcA-4qb5A:
undetectable		 3oxcA-4qb5A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 4qb5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Rhodoferax
ferrireducens) 		3 / 3 GLY A  63
ASN A  62
ARG A 111
 None
 0.77A 5w7bD-4qb5A:
undetectable		 5w7bD-4qb5A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 4qb5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE
(Rhodoferax
ferrireducens) 		4 / 8 TYR A  40
GLY A  45
SER A   0
VAL A   5
 None
 1.08A 6giqL-4qb5A:
undetectable
6giqP-4qb5A:
undetectable
6giqT-4qb5A:
undetectable		 6giqL-4qb5A:
15.71
6giqP-4qb5A:
22.94
6giqT-4qb5A:
20.44