SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 4 SER A 273
VAL A 196
PHE A 209
VAL A 314
 None
 1.48A 1o86A-4qb7A:
undetectable		 1o86A-4qb7A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 8 LYS A 214
PHE A 245
PHE A 290
LEU A 288
PHE A 254
 None
 1.29A 1v54C-4qb7A:
undetectable
1v54J-4qb7A:
undetectable		 1v54C-4qb7A:
19.89
1v54J-4qb7A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 8 LYS A 214
PHE A 245
PHE A 290
LEU A 288
PHE A 254
 None
 1.32A 2dyrC-4qb7A:
undetectable
2dyrJ-4qb7A:
undetectable		 2dyrC-4qb7A:
19.89
2dyrJ-4qb7A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 8 LYS A 214
PHE A 245
PHE A 290
LEU A 288
PHE A 254
 None
 1.31A 2eikP-4qb7A:
undetectable
2eikW-4qb7A:
undetectable		 2eikP-4qb7A:
19.89
2eikW-4qb7A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 8 LYS A 214
PHE A 245
PHE A 290
LEU A 288
PHE A 254
 None
 1.30A 2eilC-4qb7A:
undetectable
2eilJ-4qb7A:
undetectable		 2eilC-4qb7A:
19.89
2eilJ-4qb7A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 7 LYS A 214
PHE A 245
PHE A 290
LEU A 288
PHE A 254
 None
 1.30A 2eimP-4qb7A:
undetectable
2eimW-4qb7A:
undetectable		 2eimP-4qb7A:
19.89
2eimW-4qb7A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 TYR A 347
ILE A 191
LEU A 251
LEU A 215
 None
 0.94A 2zb7A-4qb7A:
undetectable		 2zb7A-4qb7A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 7 LYS A 214
PHE A 245
PHE A 290
LEU A 288
PHE A 254
 None
 1.33A 3asoP-4qb7A:
undetectable
3asoW-4qb7A:
undetectable		 3asoP-4qb7A:
19.89
3asoW-4qb7A:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLN A 190
PHE A 282
PHE A 339
LEU A 334
ASP A 362
 None
 1.21A 3gwuA-4qb7A:
undetectable		 3gwuA-4qb7A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		3 / 3 VAL A  38
VAL A 180
TRP A  96
 None
 0.96A 3l8lC-4qb7A:
undetectable
3l8lD-4qb7A:
undetectable		 3l8lC-4qb7A:
4.10
3l8lD-4qb7A:
3.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ASN A 295
PRO A 292
TYR A 223
ALA A 226
 None
None
SO4  A 416 (-4.7A)
None
 0.92A 3twpA-4qb7A:
undetectable		 3twpA-4qb7A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ASN A 295
PRO A 292
TYR A 223
ALA A 226
 None
None
SO4  A 416 (-4.7A)
None
 0.92A 3twpB-4qb7A:
undetectable		 3twpB-4qb7A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ASN A 295
PRO A 292
TYR A 223
ALA A 226
 None
None
SO4  A 416 (-4.7A)
None
 0.92A 3twpC-4qb7A:
undetectable		 3twpC-4qb7A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 ASN A 295
PRO A 292
TYR A 223
ALA A 226
 None
None
SO4  A 416 (-4.7A)
None
 0.93A 3twpD-4qb7A:
undetectable		 3twpD-4qb7A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 6 HIS A 186
GLU A  48
ASP A 159
ASN A  57
 None
 1.27A 3vywA-4qb7A:
undetectable		 3vywA-4qb7A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 5 THR A 346
ILE A 194
LYS A 195
PHE A 254
 None
None
SO4  A 401 ( 4.4A)
None
 1.29A 4acbC-4qb7A:
undetectable		 4acbC-4qb7A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM0_B_KANB302_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 11 TYR A 347
LEU A 334
THR A 299
LEU A 215
VAL A 293
 None
 1.46A 4em0B-4qb7A:
0.0		 4em0B-4qb7A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 GLY A 218
ASP A 216
PHE A 290
PHE A 339
PHE A 245
 CL  A 423 ( 3.8A)
None
None
None
None
 1.18A 4wh5A-4qb7A:
undetectable		 4wh5A-4qb7A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ASN A 301
TYR A 223
LEU A 222
PHE A 245
 None
SO4  A 416 (-4.7A)
None
None
 1.25A 4yv5B-4qb7A:
undetectable		 4yv5B-4qb7A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 8 THR A 189
THR A 338
LEU A 305
LEU A 215
 None
 0.78A 4z90F-4qb7A:
undetectable
4z90G-4qb7A:
undetectable
4z90H-4qb7A:
undetectable
4z90I-4qb7A:
undetectable
4z90J-4qb7A:
undetectable		 4z90F-4qb7A:
19.42
4z90G-4qb7A:
19.42
4z90H-4qb7A:
19.42
4z90I-4qb7A:
19.42
4z90J-4qb7A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		4 / 7 ILE A 191
LEU A 222
PHE A 245
THR A 150
 None
None
None
CL  A 420 (-3.8A)
 0.96A 5vc0A-4qb7A:
undetectable		 5vc0A-4qb7A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 4qb7 UNCHARACTERIZED
PROTEIN
(Bacteroides
vulgatus) 		5 / 12 TYR A 347
LEU A 307
ILE A 191
VAL A 148
THR A 338
 None
 1.23A 6djzB-4qb7A:
undetectable		 6djzB-4qb7A:
19.28