SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qbj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB8_0
(GRAMICIDIN A)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		3 / 3 TRP A 166
VAL A 343
TRP A 341
 None
 0.89A 1c4dA-4qbjA:
undetectable
1c4dB-4qbjA:
undetectable		 1c4dA-4qbjA:
7.30
1c4dB-4qbjA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 8 THR A 302
PRO A 303
GLY A 304
THR A 368
 None
 0.71A 1h4oB-4qbjA:
undetectable		 1h4oB-4qbjA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 8 THR A 302
PRO A 303
GLY A 304
THR A 368
 None
 0.69A 1oc3A-4qbjA:
undetectable		 1oc3A-4qbjA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 4 LEU A 168
SER A 192
LEU A 136
LEU A 164
 None
 1.04A 1yajA-4qbjA:
undetectable		 1yajA-4qbjA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 438
HIS A 265
ALA A 421
PHE A 373
TYR A 374
 None
2XQ  A 505 (-4.0A)
None
None
None
 1.41A 2g70B-4qbjA:
undetectable		 2g70B-4qbjA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 6 ARG A 236
ASN A 241
ASN A 213
LEU A 168
 None
None
2XQ  A 505 ( 3.5A)
None
 1.30A 2nyrA-4qbjA:
undetectable		 2nyrA-4qbjA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 143
LEU A 128
LEU A 168
GLY A 180
LEU A 189
 None
 1.03A 2ouzA-4qbjA:
undetectable		 2ouzA-4qbjA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		3 / 3 LEU A 436
TYR A 263
GLN A 456
 2XQ  A 505 ( 4.4A)
2XQ  A 505 (-3.8A)
None
 0.72A 2wekA-4qbjA:
undetectable		 2wekA-4qbjA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 5 VAL A 359
VAL A 358
THR A 300
THR A 368
 None
 1.25A 3bjwD-4qbjA:
undetectable		 3bjwD-4qbjA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		5 / 12 LEU A 438
GLY A 472
ILE A 489
LEU A 329
ARG A 203
 None
 1.25A 3gyqA-4qbjA:
undetectable
3gyqB-4qbjA:
undetectable		 3gyqA-4qbjA:
21.67
3gyqB-4qbjA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		3 / 3 ILE A 367
VAL A 358
ARG A 306
 None
 0.57A 3p73A-4qbjA:
undetectable		 3p73A-4qbjA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		5 / 12 PHE A 370
LEU A 320
HIS A 439
TYR A 395
ALA A 356
 None
 1.30A 3r2jC-4qbjA:
undetectable		 3r2jC-4qbjA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		5 / 12 ALA A 183
LEU A 120
ILE A 217
LEU A 230
THR A 184
 None
None
NHM  A 504 (-4.2A)
None
None
 1.10A 4ej1B-4qbjA:
undetectable		 4ej1B-4qbjA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 7 TYR A 263
LEU A 436
ASN A 434
TYR A 374
 2XQ  A 505 (-3.8A)
2XQ  A 505 ( 4.4A)
2XQ  A 505 (-3.9A)
None
 1.35A 4f8yC-4qbjA:
undetectable
4f8yD-4qbjA:
undetectable		 4f8yC-4qbjA:
17.87
4f8yD-4qbjA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 7 TYR A 263
LEU A 457
ASN A 434
TYR A 374
 2XQ  A 505 (-3.8A)
None
2XQ  A 505 (-3.9A)
None
 1.24A 4f8yC-4qbjA:
undetectable
4f8yD-4qbjA:
undetectable		 4f8yC-4qbjA:
17.87
4f8yD-4qbjA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 4 HIS A 458
ALA A 250
VAL A 252
GLU A 149
 None
NHM  A 504 ( 3.9A)
None
NHM  A 504 (-4.0A)
 1.29A 4n6pA-4qbjA:
undetectable		 4n6pA-4qbjA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 8 PHE A 370
TYR A 395
LEU A 320
PHE A 333
 None
 0.90A 4qopC-4qbjA:
undetectable		 4qopC-4qbjA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 6 TYR A 395
GLU A 211
LEU A 492
GLN A 331
 None
 1.47A 4qztA-4qbjA:
undetectable		 4qztA-4qbjA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		5 / 10 PHE A 155
VAL A 432
ASP A 431
PHE A 278
SER A 378
 None
2XQ  A 505 (-4.5A)
None
2XQ  A 505 (-3.6A)
2XQ  A 505 (-3.1A)
 1.07A 4xp1A-4qbjA:
undetectable		 4xp1A-4qbjA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		5 / 11 PHE A 155
VAL A 432
ASP A 431
PHE A 278
SER A 378
 None
2XQ  A 505 (-4.5A)
None
2XQ  A 505 (-3.6A)
2XQ  A 505 (-3.1A)
 1.12A 4xp4A-4qbjA:
undetectable		 4xp4A-4qbjA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		4 / 7 ALA A 421
ARG A 306
GLY A 304
GLU A 360
 None
 0.93A 5btgA-4qbjA:
undetectable
5btgC-4qbjA:
undetectable
5btgD-4qbjA:
undetectable		 5btgA-4qbjA:
21.30
5btgC-4qbjA:
21.30
5btgD-4qbjA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		3 / 3 VAL A 473
HIS A 439
VAL A 487
 None
 0.70A 5jmnC-4qbjA:
undetectable		 5jmnC-4qbjA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4qbj GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Aspergillus
fumigatus) 		3 / 3 GLN A 245
TYR A 244
ASN A 463
 None
 0.82A 6dwdC-4qbjA:
undetectable		 6dwdC-4qbjA:
22.69