SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qbu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 LYS A  94
ILE A 358
LEU A 386
ARG A 394
ILE A 395
 None
 1.22A 1d1gA-4qbuA:
undetectable		 1d1gA-4qbuA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 1d1vA-4qbuA:
undetectable
1d1vB-4qbuA:
undetectable		 1d1vA-4qbuA:
21.38
1d1vB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 1d1wA-4qbuA:
undetectable
1d1wB-4qbuA:
undetectable		 1d1wA-4qbuA:
21.38
1d1wB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 1d1xA-4qbuA:
undetectable
1d1xB-4qbuA:
undetectable		 1d1xA-4qbuA:
21.38
1d1xB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 1dm8A-4qbuA:
0.3
1dm8B-4qbuA:
undetectable		 1dm8A-4qbuA:
21.38
1dm8B-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 VAL A 174
LEU A 412
GLY A 373
PRO A 374
PHE A 170
 None
 1.39A 1fdsA-4qbuA:
undetectable		 1fdsA-4qbuA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		3 / 3 ARG A   9
ILE A  52
TRP A 428
 None
 1.20A 1m8eB-4qbuA:
undetectable		 1m8eB-4qbuA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 1nseA-4qbuA:
undetectable
1nseB-4qbuA:
0.5		 1nseA-4qbuA:
21.38
1nseB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 1nsiA-4qbuA:
undetectable
1nsiB-4qbuA:
undetectable		 1nsiA-4qbuA:
21.12
1nsiB-4qbuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 1nsiC-4qbuA:
undetectable
1nsiD-4qbuA:
undetectable		 1nsiC-4qbuA:
21.12
1nsiD-4qbuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 1nsiC-4qbuA:
undetectable
1nsiD-4qbuA:
undetectable		 1nsiC-4qbuA:
21.12
1nsiD-4qbuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 1p6lA-4qbuA:
undetectable
1p6lB-4qbuA:
undetectable		 1p6lA-4qbuA:
20.17
1p6lB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 1p6lA-4qbuA:
undetectable
1p6lB-4qbuA:
undetectable		 1p6lA-4qbuA:
20.17
1p6lB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 1p6mA-4qbuA:
undetectable
1p6mB-4qbuA:
undetectable		 1p6mA-4qbuA:
20.17
1p6mB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 1p6nA-4qbuA:
undetectable
1p6nB-4qbuA:
0.6		 1p6nA-4qbuA:
20.17
1p6nB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 1p6nA-4qbuA:
undetectable
1p6nB-4qbuA:
0.6		 1p6nA-4qbuA:
20.17
1p6nB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 1q2oA-4qbuA:
undetectable
1q2oB-4qbuA:
0.6		 1q2oA-4qbuA:
20.17
1q2oB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 1rs8A-4qbuA:
undetectable
1rs8B-4qbuA:
undetectable		 1rs8A-4qbuA:
20.17
1rs8B-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 1rs8A-4qbuA:
undetectable
1rs8B-4qbuA:
0.5		 1rs8A-4qbuA:
20.17
1rs8B-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 1rs9A-4qbuA:
1.0
1rs9B-4qbuA:
undetectable		 1rs9A-4qbuA:
20.17
1rs9B-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 PHE A 369
PHE A 396
ASN A 397
ASN A 362
 None
 1.42A 1t9uA-4qbuA:
2.9		 1t9uA-4qbuA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 LEU A 131
PHE A 128
ALA A 129
LEU A 211
 None
 0.82A 1ukbA-4qbuA:
undetectable		 1ukbA-4qbuA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ILE A 189
LEU A  98
ARG A 363
LEU A 386
 None
 0.96A 1v54N-4qbuA:
2.0
1v54W-4qbuA:
undetectable		 1v54N-4qbuA:
20.36
1v54W-4qbuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ALA A 187
GLU A 186
ILE A  95
LEU A 361
 None
 0.83A 1xvaA-4qbuA:
undetectable
1xvaB-4qbuA:
undetectable		 1xvaA-4qbuA:
21.97
1xvaB-4qbuA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 1zzsA-4qbuA:
undetectable
1zzsB-4qbuA:
undetectable		 1zzsA-4qbuA:
20.17
1zzsB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 1zzsA-4qbuA:
undetectable
1zzsB-4qbuA:
undetectable		 1zzsA-4qbuA:
20.17
1zzsB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZT_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 1zztA-4qbuA:
0.0
1zztB-4qbuA:
0.0		 1zztA-4qbuA:
20.17
1zztB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 11 THR A 382
LEU A  98
GLY A 190
VAL A 258
VAL A 352
 None
 1.19A 2a1nA-4qbuA:
undetectable		 2a1nA-4qbuA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 10 THR A 382
LEU A  98
GLY A 190
VAL A 258
VAL A 352
 None
 1.17A 2cp4A-4qbuA:
undetectable		 2cp4A-4qbuA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ILE A 189
LEU A  98
ARG A 363
LEU A 386
 None
 1.00A 2dyrN-4qbuA:
2.0
2dyrW-4qbuA:
undetectable		 2dyrN-4qbuA:
20.36
2dyrW-4qbuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 2hx2A-4qbuA:
0.3
2hx2B-4qbuA:
undetectable		 2hx2A-4qbuA:
20.17
2hx2B-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 2hx2A-4qbuA:
0.3
2hx2B-4qbuA:
undetectable		 2hx2A-4qbuA:
20.17
2hx2B-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 LYS A 281
LEU A 230
ILE A 254
PHE A 246
GLY A 227
 None
 1.32A 2lbdA-4qbuA:
undetectable		 2lbdA-4qbuA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 2nseA-4qbuA:
undetectable
2nseB-4qbuA:
undetectable		 2nseA-4qbuA:
21.38
2nseB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.50A 2nseA-4qbuA:
0.3
2nseB-4qbuA:
0.3		 2nseA-4qbuA:
21.38
2nseB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 2nsiA-4qbuA:
undetectable
2nsiB-4qbuA:
undetectable		 2nsiA-4qbuA:
21.12
2nsiB-4qbuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 2nsiC-4qbuA:
0.4
2nsiD-4qbuA:
undetectable		 2nsiC-4qbuA:
21.12
2nsiD-4qbuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 2nsiC-4qbuA:
0.4
2nsiD-4qbuA:
undetectable		 2nsiC-4qbuA:
21.12
2nsiD-4qbuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 ALA A 187
ILE A 358
LEU A 386
ARG A 394
PHE A 369
 None
 1.08A 2qk8A-4qbuA:
undetectable		 2qk8A-4qbuA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 8 ARG A 217
GLY A 350
GLY A 101
MET A 229
 FMT  A 500 (-2.9A)
None
None
None
 0.63A 2y6rB-4qbuA:
undetectable		 2y6rB-4qbuA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 THR A 382
LEU A  98
VAL A 258
VAL A 352
 None
 0.74A 2z97A-4qbuA:
undetectable		 2z97A-4qbuA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 ALA A 187
LEU A 325
LEU A 386
ARG A 394
PHE A 369
 None
 1.13A 3datA-4qbuA:
undetectable		 3datA-4qbuA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 3dqtA-4qbuA:
0.6
3dqtB-4qbuA:
undetectable		 3dqtA-4qbuA:
20.17
3dqtB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4qbu ZMAA
(Bacillus
cereus) 		3 / 3 ARG A   9
ILE A  52
TRP A 428
 None
 1.14A 3e68A-4qbuA:
undetectable		 3e68A-4qbuA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 PHE A 354
ILE A 358
ASN A 397
VAL A 174
ILE A 372
 None
 1.16A 3em0B-4qbuA:
undetectable		 3em0B-4qbuA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 4 GLY A 261
VAL A 259
GLY A 330
THR A 329
 None
 0.85A 3ib2A-4qbuA:
undetectable		 3ib2A-4qbuA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 3jwwA-4qbuA:
0.4
3jwwB-4qbuA:
0.0		 3jwwA-4qbuA:
21.38
3jwwB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 3jwxA-4qbuA:
0.4
3jwxB-4qbuA:
0.5		 3jwxA-4qbuA:
21.38
3jwxB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 3jwxA-4qbuA:
0.4
3jwxB-4qbuA:
0.5		 3jwxA-4qbuA:
21.38
3jwxB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.42A 3jwyA-4qbuA:
0.4
3jwyB-4qbuA:
0.8		 3jwyA-4qbuA:
21.38
3jwyB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 3jwyA-4qbuA:
0.4
3jwyB-4qbuA:
0.8		 3jwyA-4qbuA:
21.38
3jwyB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 3jwzA-4qbuA:
undetectable
3jwzB-4qbuA:
undetectable		 3jwzA-4qbuA:
21.38
3jwzB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 3jwzA-4qbuA:
undetectable
3jwzB-4qbuA:
undetectable		 3jwzA-4qbuA:
21.38
3jwzB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 8 PHE A 120
TYR A 114
ALA A 173
ALA A 169
 None
 0.95A 3l4dD-4qbuA:
undetectable		 3l4dD-4qbuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 3n5pA-4qbuA:
0.5
3n5pB-4qbuA:
undetectable		 3n5pA-4qbuA:
21.38
3n5pB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Q_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 3n5qA-4qbuA:
0.7
3n5qB-4qbuA:
0.5		 3n5qA-4qbuA:
21.38
3n5qB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 3n5rA-4qbuA:
undetectable
3n5rB-4qbuA:
undetectable		 3n5rA-4qbuA:
21.38
3n5rB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.42A 3n5sA-4qbuA:
undetectable
3n5sB-4qbuA:
0.8		 3n5sA-4qbuA:
21.38
3n5sB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.44A 3n5sA-4qbuA:
undetectable
3n5sB-4qbuA:
0.8		 3n5sA-4qbuA:
21.38
3n5sB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 3n5tA-4qbuA:
undetectable
3n5tB-4qbuA:
undetectable		 3n5tA-4qbuA:
21.38
3n5tB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.43A 3n67A-4qbuA:
0.4
3n67B-4qbuA:
undetectable		 3n67A-4qbuA:
21.38
3n67B-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N67_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 3n67A-4qbuA:
0.3
3n67B-4qbuA:
0.3		 3n67A-4qbuA:
21.38
3n67B-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N68_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 3n68A-4qbuA:
0.4
3n68B-4qbuA:
0.2		 3n68A-4qbuA:
21.38
3n68B-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N68_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 3n68A-4qbuA:
0.4
3n68B-4qbuA:
0.1		 3n68A-4qbuA:
21.38
3n68B-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N69_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.42A 3n69A-4qbuA:
0.4
3n69B-4qbuA:
0.3		 3n69A-4qbuA:
21.38
3n69B-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N69_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 3n69A-4qbuA:
0.4
3n69B-4qbuA:
0.3		 3n69A-4qbuA:
21.38
3n69B-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 3n6aA-4qbuA:
0.4
3n6aB-4qbuA:
0.3		 3n6aA-4qbuA:
21.38
3n6aB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 3n6aA-4qbuA:
0.4
3n6aB-4qbuA:
0.4		 3n6aA-4qbuA:
21.38
3n6aB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.43A 3n6eA-4qbuA:
0.7
3n6eB-4qbuA:
0.3		 3n6eA-4qbuA:
21.38
3n6eB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 3n6eA-4qbuA:
0.7
3n6eB-4qbuA:
0.3		 3n6eA-4qbuA:
21.38
3n6eB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 3n6fA-4qbuA:
undetectable
3n6fB-4qbuA:
0.7		 3n6fA-4qbuA:
21.38
3n6fB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 3n6fA-4qbuA:
undetectable
3n6fB-4qbuA:
0.7		 3n6fA-4qbuA:
21.38
3n6fB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 3n6gA-4qbuA:
0.8
3n6gB-4qbuA:
undetectable		 3n6gA-4qbuA:
21.38
3n6gB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.43A 3n6gA-4qbuA:
0.8
3n6gB-4qbuA:
undetectable		 3n6gA-4qbuA:
21.38
3n6gB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 3nleA-4qbuA:
0.6
3nleB-4qbuA:
0.6		 3nleA-4qbuA:
21.38
3nleB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 3nleA-4qbuA:
0.6
3nleB-4qbuA:
0.6		 3nleA-4qbuA:
21.38
3nleB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.43A 3nlfA-4qbuA:
undetectable
3nlfB-4qbuA:
0.7		 3nlfA-4qbuA:
21.38
3nlfB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 3nlgA-4qbuA:
0.4
3nlgB-4qbuA:
undetectable		 3nlgA-4qbuA:
21.38
3nlgB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 3nlgA-4qbuA:
0.4
3nlgB-4qbuA:
0.6		 3nlgA-4qbuA:
21.38
3nlgB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 3nlhA-4qbuA:
undetectable
3nlhB-4qbuA:
0.6		 3nlhA-4qbuA:
21.38
3nlhB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 3nlhA-4qbuA:
undetectable
3nlhB-4qbuA:
0.6		 3nlhA-4qbuA:
21.38
3nlhB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 3nliA-4qbuA:
0.7
3nliB-4qbuA:
undetectable		 3nliA-4qbuA:
21.38
3nliB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 3nliA-4qbuA:
0.7
3nliB-4qbuA:
undetectable		 3nliA-4qbuA:
21.38
3nliB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.42A 3nluA-4qbuA:
undetectable
3nluB-4qbuA:
undetectable		 3nluA-4qbuA:
21.38
3nluB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.43A 3nluA-4qbuA:
0.0
3nluB-4qbuA:
0.0		 3nluA-4qbuA:
21.38
3nluB-4qbuA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 3nosA-4qbuA:
0.6
3nosB-4qbuA:
0.6		 3nosA-4qbuA:
21.83
3nosB-4qbuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_B_H4BB1011_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 3nosA-4qbuA:
0.6
3nosB-4qbuA:
0.6		 3nosA-4qbuA:
21.83
3nosB-4qbuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.43A 3pnhA-4qbuA:
0.5
3pnhB-4qbuA:
0.8		 3pnhA-4qbuA:
20.17
3pnhB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 3pnhA-4qbuA:
0.5
3pnhB-4qbuA:
0.8		 3pnhA-4qbuA:
20.17
3pnhB-4qbuA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 3rqoA-4qbuA:
0.7
3rqoB-4qbuA:
undetectable		 3rqoA-4qbuA:
21.53
3rqoB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 3rqoA-4qbuA:
0.7
3rqoB-4qbuA:
undetectable		 3rqoA-4qbuA:
21.53
3rqoB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 3rqpA-4qbuA:
undetectable
3rqpB-4qbuA:
0.7		 3rqpA-4qbuA:
21.53
3rqpB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 THR A 398
GLY A 375
LEU A 143
VAL A 174
ALA A 173
 None
 1.22A 3t7vA-4qbuA:
undetectable		 3t7vA-4qbuA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 3ufrA-4qbuA:
undetectable
3ufrB-4qbuA:
0.4		 3ufrA-4qbuA:
22.58
3ufrB-4qbuA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 8 ARG A 217
GLY A 350
GLY A 101
MET A 229
 FMT  A 500 (-2.9A)
None
None
None
 0.66A 3v3nB-4qbuA:
undetectable		 3v3nB-4qbuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 8 ARG A 217
GLY A 350
GLY A 101
MET A 229
 FMT  A 500 (-2.9A)
None
None
None
 0.67A 3v3nC-4qbuA:
undetectable		 3v3nC-4qbuA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 4 ASP A  45
THR A  49
VAL A  41
SER A  47
 None
 1.23A 3wxoA-4qbuA:
undetectable		 3wxoA-4qbuA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4c3aA-4qbuA:
undetectable
4c3aB-4qbuA:
undetectable		 4c3aA-4qbuA:
21.53
4c3aB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 4c3aA-4qbuA:
undetectable
4c3aB-4qbuA:
undetectable		 4c3aA-4qbuA:
21.53
4c3aB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 10 THR A 382
LEU A  98
GLY A 190
VAL A 258
VAL A 352
 None
 1.21A 4c9nB-4qbuA:
undetectable		 4c9nB-4qbuA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 9 THR A 382
LEU A  98
GLY A 190
VAL A 258
VAL A 352
 None
 1.19A 4c9pA-4qbuA:
undetectable		 4c9pA-4qbuA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 10 THR A 382
LEU A  98
GLY A 190
VAL A 258
VAL A 352
 None
 1.21A 4c9pB-4qbuA:
undetectable		 4c9pB-4qbuA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 4carA-4qbuA:
undetectable
4carB-4qbuA:
undetectable		 4carA-4qbuA:
21.53
4carB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4carA-4qbuA:
undetectable
4carB-4qbuA:
undetectable		 4carA-4qbuA:
21.53
4carB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 4cftA-4qbuA:
undetectable
4cftB-4qbuA:
undetectable		 4cftA-4qbuA:
21.53
4cftB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 4ctyA-4qbuA:
undetectable
4ctyB-4qbuA:
undetectable		 4ctyA-4qbuA:
21.53
4ctyB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.42A 4ctyA-4qbuA:
undetectable
4ctyB-4qbuA:
0.6		 4ctyA-4qbuA:
21.53
4ctyB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.42A 4ctzA-4qbuA:
0.5
4ctzB-4qbuA:
undetectable		 4ctzA-4qbuA:
21.53
4ctzB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 4ctzA-4qbuA:
0.6
4ctzB-4qbuA:
undetectable		 4ctzA-4qbuA:
21.53
4ctzB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 4cu0A-4qbuA:
0.9
4cu0B-4qbuA:
0.8		 4cu0A-4qbuA:
21.53
4cu0B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4cu0A-4qbuA:
0.9
4cu0B-4qbuA:
0.8		 4cu0A-4qbuA:
21.53
4cu0B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 4cu1A-4qbuA:
undetectable
4cu1B-4qbuA:
undetectable		 4cu1A-4qbuA:
21.53
4cu1B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4cwvA-4qbuA:
0.5
4cwvB-4qbuA:
1.1		 4cwvA-4qbuA:
21.53
4cwvB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 4cwwA-4qbuA:
0.7
4cwwB-4qbuA:
undetectable		 4cwwA-4qbuA:
21.53
4cwwB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 4cwwA-4qbuA:
0.7
4cwwB-4qbuA:
undetectable		 4cwwA-4qbuA:
21.53
4cwwB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 4cwxA-4qbuA:
undetectable
4cwxB-4qbuA:
0.9		 4cwxA-4qbuA:
21.53
4cwxB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4cwxA-4qbuA:
undetectable
4cwxB-4qbuA:
1.0		 4cwxA-4qbuA:
21.53
4cwxB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4cwyA-4qbuA:
undetectable
4cwyB-4qbuA:
undetectable		 4cwyA-4qbuA:
21.53
4cwyB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 4cwyA-4qbuA:
undetectable
4cwyB-4qbuA:
undetectable		 4cwyA-4qbuA:
21.53
4cwyB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 4cwzA-4qbuA:
0.8
4cwzB-4qbuA:
0.8		 4cwzA-4qbuA:
21.53
4cwzB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 4cwzA-4qbuA:
0.8
4cwzB-4qbuA:
0.8		 4cwzA-4qbuA:
21.53
4cwzB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 4cx0A-4qbuA:
undetectable
4cx0B-4qbuA:
0.7		 4cx0A-4qbuA:
21.53
4cx0B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4cx0A-4qbuA:
undetectable
4cx0B-4qbuA:
0.7		 4cx0A-4qbuA:
21.53
4cx0B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_D_H4BD600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4cx7C-4qbuA:
undetectable
4cx7D-4qbuA:
undetectable		 4cx7C-4qbuA:
21.12
4cx7D-4qbuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.50A 4d1oA-4qbuA:
undetectable
4d1oB-4qbuA:
undetectable		 4d1oA-4qbuA:
21.46
4d1oB-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 4d1pA-4qbuA:
0.4
4d1pB-4qbuA:
0.4		 4d1pA-4qbuA:
21.46
4d1pB-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4d1pA-4qbuA:
undetectable
4d1pB-4qbuA:
1.0		 4d1pA-4qbuA:
21.46
4d1pB-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 4d35A-4qbuA:
undetectable
4d35B-4qbuA:
0.3		 4d35A-4qbuA:
21.53
4d35B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 4d36A-4qbuA:
0.6
4d36B-4qbuA:
0.7		 4d36A-4qbuA:
21.53
4d36B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.50A 4d36A-4qbuA:
0.6
4d36B-4qbuA:
0.7		 4d36A-4qbuA:
21.53
4d36B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 4d37A-4qbuA:
undetectable
4d37B-4qbuA:
0.8		 4d37A-4qbuA:
21.53
4d37B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 4d39A-4qbuA:
0.6
4d39B-4qbuA:
undetectable		 4d39A-4qbuA:
21.53
4d39B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 4d39A-4qbuA:
0.6
4d39B-4qbuA:
undetectable		 4d39A-4qbuA:
21.53
4d39B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4imxA-4qbuA:
undetectable
4imxB-4qbuA:
undetectable		 4imxA-4qbuA:
21.13
4imxB-4qbuA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 4imxA-4qbuA:
undetectable
4imxB-4qbuA:
undetectable		 4imxA-4qbuA:
21.13
4imxB-4qbuA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 4jskA-4qbuA:
0.4
4jskB-4qbuA:
0.4		 4jskA-4qbuA:
21.53
4jskB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 4jskA-4qbuA:
undetectable
4jskB-4qbuA:
0.9		 4jskA-4qbuA:
21.53
4jskB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.43A 4jslA-4qbuA:
undetectable
4jslB-4qbuA:
0.6		 4jslA-4qbuA:
21.53
4jslB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.44A 4jslA-4qbuA:
undetectable
4jslB-4qbuA:
0.6		 4jslA-4qbuA:
21.53
4jslB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 4jsmA-4qbuA:
0.7
4jsmB-4qbuA:
undetectable		 4jsmA-4qbuA:
21.53
4jsmB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 4jsmA-4qbuA:
0.7
4jsmB-4qbuA:
undetectable		 4jsmA-4qbuA:
21.53
4jsmB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 10 THR A 382
LEU A  98
GLY A 190
VAL A 258
VAL A 352
 None
 1.20A 4jx1B-4qbuA:
undetectable		 4jx1B-4qbuA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 4k5hA-4qbuA:
undetectable
4k5hB-4qbuA:
0.7		 4k5hA-4qbuA:
21.53
4k5hB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4k5iA-4qbuA:
undetectable
4k5iB-4qbuA:
undetectable		 4k5iA-4qbuA:
21.53
4k5iB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 4k5jA-4qbuA:
undetectable
4k5jB-4qbuA:
undetectable		 4k5jA-4qbuA:
21.53
4k5jB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 4k5kA-4qbuA:
0.9
4k5kB-4qbuA:
undetectable		 4k5kA-4qbuA:
21.53
4k5kB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 4k5kA-4qbuA:
0.9
4k5kB-4qbuA:
undetectable		 4k5kA-4qbuA:
21.53
4k5kB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 4kcpA-4qbuA:
undetectable
4kcpB-4qbuA:
0.6		 4kcpA-4qbuA:
21.53
4kcpB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4kcqA-4qbuA:
1.0
4kcqB-4qbuA:
0.8		 4kcqA-4qbuA:
21.53
4kcqB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 4kcqA-4qbuA:
1.0
4kcqB-4qbuA:
0.8		 4kcqA-4qbuA:
21.53
4kcqB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4kcrA-4qbuA:
0.6
4kcrB-4qbuA:
0.5		 4kcrA-4qbuA:
21.53
4kcrB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4kcrA-4qbuA:
0.6
4kcrB-4qbuA:
0.5		 4kcrA-4qbuA:
21.53
4kcrB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 4kcsA-4qbuA:
0.6
4kcsB-4qbuA:
undetectable		 4kcsA-4qbuA:
21.53
4kcsB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 4kcsA-4qbuA:
0.6
4kcsB-4qbuA:
undetectable		 4kcsA-4qbuA:
21.53
4kcsB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 8 THR A 382
LEU A  98
VAL A 258
VAL A 352
 None
 0.64A 4l4bA-4qbuA:
undetectable		 4l4bA-4qbuA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 4 VAL A 228
THR A 269
GLU A 270
GLU A 271
 None
 1.20A 4l78A-4qbuA:
undetectable		 4l78A-4qbuA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 4luwA-4qbuA:
undetectable
4luwB-4qbuA:
undetectable		 4luwA-4qbuA:
21.89
4luwB-4qbuA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4luwA-4qbuA:
undetectable
4luwB-4qbuA:
undetectable		 4luwA-4qbuA:
21.89
4luwB-4qbuA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NOS_B_H4BB1011_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 4nosA-4qbuA:
undetectable
4nosB-4qbuA:
undetectable		 4nosA-4qbuA:
21.24
4nosB-4qbuA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 VAL A 258
LEU A  98
PHE A 369
PHE A 354
GLY A 357
 None
 1.36A 4pevC-4qbuA:
3.0		 4pevC-4qbuA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 4uh7A-4qbuA:
0.3
4uh7B-4qbuA:
undetectable		 4uh7A-4qbuA:
21.53
4uh7B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 4uh7A-4qbuA:
0.3
4uh7B-4qbuA:
undetectable		 4uh7A-4qbuA:
21.53
4uh7B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 4uh8A-4qbuA:
undetectable
4uh8B-4qbuA:
undetectable		 4uh8A-4qbuA:
21.53
4uh8B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 4uh8A-4qbuA:
undetectable
4uh8B-4qbuA:
undetectable		 4uh8A-4qbuA:
21.53
4uh8B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 4uh9A-4qbuA:
undetectable
4uh9B-4qbuA:
undetectable		 4uh9A-4qbuA:
21.53
4uh9B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 4uh9A-4qbuA:
undetectable
4uh9B-4qbuA:
undetectable		 4uh9A-4qbuA:
21.53
4uh9B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4uhaA-4qbuA:
0.8
4uhaB-4qbuA:
0.8		 4uhaA-4qbuA:
21.53
4uhaB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 4uhaA-4qbuA:
0.8
4uhaB-4qbuA:
0.8		 4uhaA-4qbuA:
21.53
4uhaB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 4upqA-4qbuA:
undetectable
4upqB-4qbuA:
undetectable		 4upqA-4qbuA:
21.53
4upqB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 4upqA-4qbuA:
undetectable
4upqB-4qbuA:
undetectable		 4upqA-4qbuA:
21.53
4upqB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.44A 4uprA-4qbuA:
undetectable
4uprB-4qbuA:
0.6		 4uprA-4qbuA:
21.53
4uprB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 4uprA-4qbuA:
undetectable
4uprB-4qbuA:
0.6		 4uprA-4qbuA:
21.53
4uprB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.43A 4upsA-4qbuA:
undetectable
4upsB-4qbuA:
1.2		 4upsA-4qbuA:
21.53
4upsB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 4upsA-4qbuA:
undetectable
4upsB-4qbuA:
1.2		 4upsA-4qbuA:
21.53
4upsB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.43A 4uptA-4qbuA:
undetectable
4uptB-4qbuA:
undetectable		 4uptA-4qbuA:
21.53
4uptB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 4uptA-4qbuA:
undetectable
4uptB-4qbuA:
undetectable		 4uptA-4qbuA:
21.53
4uptB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.41A 4v3uC-4qbuA:
undetectable
4v3uD-4qbuA:
undetectable		 4v3uC-4qbuA:
22.61
4v3uD-4qbuA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 10 LEU A  50
THR A  28
LEU A  31
LEU A  75
LEU A  63
 None
 1.05A 4z91A-4qbuA:
undetectable
4z91B-4qbuA:
undetectable
4z91C-4qbuA:
1.2
4z91D-4qbuA:
1.3
4z91E-4qbuA:
undetectable		 4z91A-4qbuA:
21.43
4z91B-4qbuA:
21.43
4z91C-4qbuA:
21.43
4z91D-4qbuA:
21.43
4z91E-4qbuA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 5adkA-4qbuA:
0.8
5adkB-4qbuA:
undetectable		 5adkA-4qbuA:
21.53
5adkB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 5admA-4qbuA:
undetectable
5admB-4qbuA:
0.7		 5admA-4qbuA:
21.53
5admB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 5admA-4qbuA:
undetectable
5admB-4qbuA:
0.7		 5admA-4qbuA:
21.53
5admB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ILE A 189
LEU A  98
ARG A 363
LEU A 386
 None
 0.87A 5b1bA-4qbuA:
undetectable
5b1bJ-4qbuA:
undetectable		 5b1bA-4qbuA:
20.36
5b1bJ-4qbuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 5fj2A-4qbuA:
undetectable
5fj2B-4qbuA:
undetectable		 5fj2A-4qbuA:
21.53
5fj2B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.50A 5fj2A-4qbuA:
undetectable
5fj2B-4qbuA:
undetectable		 5fj2A-4qbuA:
21.53
5fj2B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 5fj3A-4qbuA:
undetectable
5fj3B-4qbuA:
0.8		 5fj3A-4qbuA:
21.53
5fj3B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 5fvyA-4qbuA:
undetectable
5fvyB-4qbuA:
undetectable		 5fvyA-4qbuA:
21.53
5fvyB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 5fvzA-4qbuA:
undetectable
5fvzB-4qbuA:
0.8		 5fvzA-4qbuA:
21.53
5fvzB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 5fvzA-4qbuA:
undetectable
5fvzB-4qbuA:
0.8		 5fvzA-4qbuA:
21.53
5fvzB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 4 LEU A  14
LEU A  75
GLY A  71
GLU A  70
 None
 1.15A 5hhjA-4qbuA:
undetectable		 5hhjA-4qbuA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ILE A 189
LEU A  98
ARG A 363
LEU A 386
 None
 0.93A 5iy5A-4qbuA:
undetectable
5iy5J-4qbuA:
undetectable		 5iy5A-4qbuA:
20.36
5iy5J-4qbuA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 LEU A 412
PHE A 411
LEU A 113
PHE A 120
 None
 1.23A 5iy5P-4qbuA:
undetectable
5iy5W-4qbuA:
undetectable		 5iy5P-4qbuA:
19.50
5iy5W-4qbuA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 4qbu ZMAA
(Bacillus
cereus) 		5 / 12 ILE A 358
LEU A 381
PHE A 354
ARG A 353
GLY A 357
 None
 1.30A 5k7uA-4qbuA:
undetectable		 5k7uA-4qbuA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 4qbu ZMAA
(Bacillus
cereus) 		6 / 9 ILE A 372
GLY A 373
VAL A 174
ILE A 416
ASN A 397
LEU A 412
 None
 1.37A 5lw1B-4qbuA:
undetectable		 5lw1B-4qbuA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.47A 5uo8A-4qbuA:
0.0
5uo8B-4qbuA:
0.0		 5uo8A-4qbuA:
21.46
5uo8B-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 5uo8C-4qbuA:
0.0
5uo8D-4qbuA:
undetectable		 5uo8C-4qbuA:
21.46
5uo8D-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.42A 5uo9C-4qbuA:
undetectable
5uo9D-4qbuA:
undetectable		 5uo9C-4qbuA:
21.46
5uo9D-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 5uodA-4qbuA:
undetectable
5uodB-4qbuA:
undetectable		 5uodA-4qbuA:
21.53
5uodB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 5uodA-4qbuA:
undetectable
5uodB-4qbuA:
undetectable		 5uodA-4qbuA:
21.53
5uodB-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 5vv6A-4qbuA:
undetectable
5vv6B-4qbuA:
undetectable		 5vv6A-4qbuA:
21.53
5vv6B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 5vv6A-4qbuA:
undetectable
5vv6B-4qbuA:
undetectable		 5vv6A-4qbuA:
21.53
5vv6B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.45A 5vv7A-4qbuA:
undetectable
5vv7B-4qbuA:
0.7		 5vv7A-4qbuA:
21.53
5vv7B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 5vv8A-4qbuA:
undetectable
5vv8B-4qbuA:
undetectable		 5vv8A-4qbuA:
21.53
5vv8B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 5vv8A-4qbuA:
undetectable
5vv8B-4qbuA:
undetectable		 5vv8A-4qbuA:
21.53
5vv8B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.48A 5vv9A-4qbuA:
undetectable
5vv9B-4qbuA:
0.9		 5vv9A-4qbuA:
21.53
5vv9B-4qbuA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.49A 5vvbA-4qbuA:
0.5
5vvbB-4qbuA:
0.0		 5vvbA-4qbuA:
21.46
5vvbB-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.46A 5vvbA-4qbuA:
0.0
5vvbB-4qbuA:
undetectable		 5vvbA-4qbuA:
21.46
5vvbB-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 5vvbC-4qbuA:
0.5
5vvbD-4qbuA:
0.5		 5vvbC-4qbuA:
21.46
5vvbD-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.49A 5vvbC-4qbuA:
undetectable
5vvbD-4qbuA:
undetectable		 5vvbC-4qbuA:
21.46
5vvbD-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 5vvcA-4qbuA:
undetectable
5vvcB-4qbuA:
0.0		 5vvcA-4qbuA:
21.46
5vvcB-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 5vvcA-4qbuA:
0.0
5vvcB-4qbuA:
0.5		 5vvcA-4qbuA:
21.46
5vvcB-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.46A 5vvcC-4qbuA:
0.0
5vvcD-4qbuA:
0.0		 5vvcC-4qbuA:
21.46
5vvcD-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.45A 5vvcC-4qbuA:
0.0
5vvcD-4qbuA:
undetectable		 5vvcC-4qbuA:
21.46
5vvcD-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.50A 5vvdA-4qbuA:
0.0
5vvdB-4qbuA:
0.0		 5vvdA-4qbuA:
21.46
5vvdB-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 5vvdC-4qbuA:
undetectable
5vvdD-4qbuA:
undetectable		 5vvdC-4qbuA:
21.46
5vvdD-4qbuA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 ILE A 189
LEU A  98
ARG A 363
LEU A 386
 None
 0.84A 5xdqA-4qbuA:
undetectable
5xdqJ-4qbuA:
undetectable		 5xdqA-4qbuA:
20.36
5xdqJ-4qbuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 LEU A 412
PHE A 411
LEU A 113
PHE A 120
 None
 1.26A 5xdxC-4qbuA:
undetectable
5xdxJ-4qbuA:
undetectable		 5xdxC-4qbuA:
19.91
5xdxJ-4qbuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 LEU A 412
PHE A 411
LEU A 113
PHE A 120
 None
 1.22A 5xdxP-4qbuA:
undetectable
5xdxW-4qbuA:
undetectable		 5xdxP-4qbuA:
19.91
5xdxW-4qbuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 8 ILE A 189
LEU A  98
ARG A 363
LEU A 386
 None
 0.89A 5zcqN-4qbuA:
undetectable
5zcqW-4qbuA:
undetectable		 5zcqN-4qbuA:
20.36
5zcqW-4qbuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.50A 6av6A-4qbuA:
undetectable
6av6B-4qbuA:
undetectable		 6av6A-4qbuA:
10.38
6av6B-4qbuA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 6av7C-4qbuA:
undetectable
6av7D-4qbuA:
0.0		 6av7C-4qbuA:
10.38
6av7D-4qbuA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 PHE A  97
LEU A 201
CYH A 200
ILE A 130
 None
 0.69A 6b5vA-4qbuA:
0.0
6b5vC-4qbuA:
undetectable		 6b5vA-4qbuA:
10.51
6b5vC-4qbuA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 PHE A  97
LEU A 201
CYH A 200
ILE A 130
 None
 0.69A 6b5vC-4qbuA:
undetectable
6b5vD-4qbuA:
0.0		 6b5vC-4qbuA:
10.51
6b5vD-4qbuA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 7 PHE A  97
LEU A 201
CYH A 200
ILE A 130
 None
 0.70A 6b5vB-4qbuA:
undetectable
6b5vD-4qbuA:
0.0		 6b5vB-4qbuA:
10.51
6b5vD-4qbuA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 TRP A 428
PHE A 431
GLU A 429
ARG A   9
 None
 1.48A 6cifA-4qbuA:
0.0
6cifB-4qbuA:
0.0		 6cifA-4qbuA:
10.38
6cifB-4qbuA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4qbu ZMAA
(Bacillus
cereus) 		4 / 5 ILE A 189
LEU A  98
ARG A 363
LEU A 386
 None
 0.93A 6nmpN-4qbuA:
2.0
6nmpW-4qbuA:
undetectable		 6nmpN-4qbuA:
20.36
6nmpW-4qbuA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 4qbu ZMAA
(Bacillus
cereus) 		4 / 6 ARG A   9
TRP A 428
PHE A 431
GLU A 429
 None
 1.47A 9nseA-4qbuA:
undetectable
9nseB-4qbuA:
0.6		 9nseA-4qbuA:
21.38
9nseB-4qbuA:
21.38