SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qd2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_D_DESD128_1
(TRANSTHYRETIN)		 4qd2 HEMAGGLUTININ
COMPONENT HA70
(Clostridium
botulinum) 		4 / 4 LYS A 419
LEU A 504
LEU A 507
SER A 510
 None
 1.44A 1tz8D-4qd2A:
undetectable		 1tz8D-4qd2A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4qd2 HEMAGGLUTININ
COMPONENT HA70
(Clostridium
botulinum) 		5 / 12 HIS A 524
LEU A 557
ILE A 543
PRO A 544
SER A 553
 None
 1.21A 3nrrB-4qd2A:
undetectable		 3nrrB-4qd2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4qd2 HEMAGGLUTININ
COMPONENT HA70
(Clostridium
botulinum) 		3 / 3 TYR A 561
ARG A 619
SER A 560
 None
 0.87A 4khpI-4qd2A:
undetectable
4khpJ-4qd2A:
undetectable		 4khpI-4qd2A:
16.40
4khpJ-4qd2A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 4qd2 HEMAGGLUTININ
COMPONENT HA70
(Clostridium
botulinum) 		3 / 3 LEU A 474
MET A 508
TYR A 432
 None
 0.90A 4p6xG-4qd2A:
undetectable		 4p6xG-4qd2A:
21.63