SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 4qd9 THIOESTERASE PA1618
(Pseudomonas
aeruginosa) 		4 / 6 ALA A  31
SER A 128
TRP A 116
TRP A   4
 None
 1.20A 1gahA-4qd9A:
undetectable		 1gahA-4qd9A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 4qd9 THIOESTERASE PA1618
(Pseudomonas
aeruginosa) 		4 / 6 ASP A 124
GLY A 125
PRO A 127
SER A 128
 None
 0.99A 1n4fA-4qd9A:
undetectable		 1n4fA-4qd9A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 4qd9 THIOESTERASE PA1618
(Pseudomonas
aeruginosa) 		5 / 12 SER A  65
LEU A 120
ILE A  27
ALA A  39
ARG A 132
 None
 1.19A 2v0mC-4qd9A:
undetectable		 2v0mC-4qd9A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 4qd9 THIOESTERASE PA1618
(Pseudomonas
aeruginosa) 		5 / 9 LEU A  10
THR A 101
ALA A  39
LEU A  13
VAL A 103
 None
 1.37A 3ozkA-4qd9A:
undetectable		 3ozkA-4qd9A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 4qd9 THIOESTERASE PA1618
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  10
THR A 101
ALA A  39
LEU A  13
 None
 0.96A 4pwjA-4qd9A:
undetectable		 4pwjA-4qd9A:
21.08