SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		4 / 7 GLY A 174
ALA A 215
THR A 120
THR A 184
 None
 0.87A 1c9sT-4qdiA:
undetectable
1c9sU-4qdiA:
undetectable		 1c9sT-4qdiA:
9.87
1c9sU-4qdiA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 PHE A 273
ALA A 261
LEU A 275
LEU A 311
ALA A 302
 None
 1.12A 1h9zA-4qdiA:
undetectable		 1h9zA-4qdiA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 121
GLU A 205
SER A 123
ASN A 197
ILE A 195
 None
None
ATP  A 501 (-3.7A)
ATP  A 501 (-4.5A)
None
 1.16A 1odiA-4qdiA:
3.6		 1odiA-4qdiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 121
GLU A 205
SER A 123
ASN A 197
ILE A 195
 None
None
ATP  A 501 (-3.7A)
ATP  A 501 (-4.5A)
None
 1.15A 1odiB-4qdiA:
3.4		 1odiB-4qdiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 121
GLU A 205
SER A 123
ASN A 197
ILE A 195
 None
None
ATP  A 501 (-3.7A)
ATP  A 501 (-4.5A)
None
 1.16A 1odiC-4qdiA:
3.3		 1odiC-4qdiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 121
GLU A 205
SER A 123
ASN A 197
ILE A 195
 None
None
ATP  A 501 (-3.7A)
ATP  A 501 (-4.5A)
None
 1.15A 1odiD-4qdiA:
3.5		 1odiD-4qdiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 121
GLU A 205
SER A 123
ASN A 197
ILE A 195
 None
None
ATP  A 501 (-3.7A)
ATP  A 501 (-4.5A)
None
 1.15A 1odiE-4qdiA:
3.5		 1odiE-4qdiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 121
GLU A 205
SER A 123
ASN A 197
ILE A 195
 None
None
ATP  A 501 (-3.7A)
ATP  A 501 (-4.5A)
None
 1.15A 1odiF-4qdiA:
3.6		 1odiF-4qdiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 12 ASN A 150
GLY A 147
ASN A 176
ILE A 212
GLY A 121
 None
 1.11A 1q8jB-4qdiA:
3.1		 1q8jB-4qdiA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_1
(RETINOIC ACID
RECEPTOR, BETA)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 12 PHE A 338
LEU A 428
LEU A 431
ILE A 432
LEU A 458
 None
 0.96A 1xdkF-4qdiA:
undetectable		 1xdkF-4qdiA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 12 ALA A 407
ALA A 354
ALA A 353
ARG A 351
ILE A 371
 None
 0.98A 2nyrA-4qdiA:
3.5		 2nyrA-4qdiA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		4 / 6 THR A 453
THR A 457
ASP A 340
ASN A 329
 None
 0.96A 2okcA-4qdiA:
undetectable		 2okcA-4qdiA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		4 / 7 TYR A 106
TRP A  14
GLN A  24
ILE A  40
 EDO  A 505 ( 4.8A)
EDO  A 505 (-4.1A)
None
None
 1.13A 2ph9A-4qdiA:
undetectable
2ph9B-4qdiA:
undetectable		 2ph9A-4qdiA:
18.26
2ph9B-4qdiA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 369
THR A 342
PHE A 403
ALA A 404
GLN A 402
 None
 1.15A 3id5B-4qdiA:
3.9		 3id5B-4qdiA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 GLY A 369
THR A 342
PHE A 403
ALA A 404
GLN A 402
 None
 1.15A 3id5F-4qdiA:
undetectable		 3id5F-4qdiA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 369
THR A 342
PHE A 403
ALA A 404
GLN A 402
 None
 1.11A 3id6C-4qdiA:
undetectable		 3id6C-4qdiA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 10 GLN A 295
ALA A 297
ALA A 299
ALA A 300
VAL A 170
 None
 1.03A 4j6cB-4qdiA:
undetectable		 4j6cB-4qdiA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 12 GLN A 295
ALA A 297
ALA A 299
ALA A 300
VAL A 170
 None
 1.01A 4jbtA-4qdiA:
undetectable		 4jbtA-4qdiA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 12 GLY A 121
GLY A 174
ASP A 235
ALA A 299
THR A 298
 None
 0.98A 4uckB-4qdiA:
undetectable		 4uckB-4qdiA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 LEU A 385
PHE A 403
GLY A 449
ALA A 399
PHE A 452
 None
 1.17A 4wnuA-4qdiA:
undetectable		 4wnuA-4qdiA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 ALA A 175
GLY A 179
VAL A 155
LEU A 100
LEU A 153
 None
 1.06A 4zmeA-4qdiA:
undetectable		 4zmeA-4qdiA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		4 / 5 GLU A 130
THR A 126
THR A 342
HIS A 454
 None
MG  A 503 ( 3.6A)
None
None
 1.13A 5axaA-4qdiA:
3.3		 5axaA-4qdiA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		4 / 5 GLU A 130
THR A 126
THR A 342
HIS A 454
 None
MG  A 503 ( 3.6A)
None
None
 1.15A 5axaC-4qdiA:
3.3		 5axaC-4qdiA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 ALA A 175
GLY A 174
GLU A 172
GLY A 199
ASN A 197
 None
None
MG  A 503 (-2.7A)
None
ATP  A 501 (-4.5A)
 1.07A 5ayfA-4qdiA:
undetectable		 5ayfA-4qdiA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 11 VAL A 400
VAL A 367
VAL A 398
ILE A 432
LEU A 458
 None
 1.05A 5e4dB-4qdiA:
undetectable		 5e4dB-4qdiA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		4 / 8 THR A 184
GLY A 174
ALA A 215
THR A 120
 None
 0.89A 5eezL-4qdiA:
undetectable
5eezV-4qdiA:
undetectable		 5eezL-4qdiA:
9.87
5eezV-4qdiA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		4 / 8 THR A 184
GLY A 174
ALA A 215
THR A 120
 None
 0.89A 5ef1L-4qdiA:
undetectable
5ef1V-4qdiA:
undetectable		 5ef1L-4qdiA:
9.87
5ef1V-4qdiA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4qdi UDP-N-ACETYLMURAMOYL
-TRIPEPTIDE--D-ALANY
L-D-ALANINE LIGASE
(Acinetobacter
baumannii) 		5 / 9 ASN A 296
ALA A 299
ILE A 117
GLY A 194
ILE A 195
 ATP  A 501 (-3.1A)
None
None
None
None
 1.15A 5kr2A-4qdiA:
undetectable		 5kr2A-4qdiA:
13.07