SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qdn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4qdn FLAGELLAR PROTEIN
FLGJ [PEPTIDOGLYCAN
HYDROLASE]
(Thermotoga
maritima) 		5 / 12 LEU A  46
PHE A   5
ALA A  13
SER A  12
LEU A  16
 None
 1.26A 3n8xA-4qdnA:
undetectable		 3n8xA-4qdnA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 4qdn FLAGELLAR PROTEIN
FLGJ [PEPTIDOGLYCAN
HYDROLASE]
(Thermotoga
maritima) 		4 / 5 GLU A  82
ARG A   8
PRO A  81
SER A  84
 None
 1.32A 4k17B-4qdnA:
undetectable		 4k17B-4qdnA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 4qdn FLAGELLAR PROTEIN
FLGJ [PEPTIDOGLYCAN
HYDROLASE]
(Thermotoga
maritima) 		4 / 4 LEU A  27
SER A  12
LEU A  46
LEU A  89
 None
 1.05A 4n09A-4qdnA:
undetectable		 4n09A-4qdnA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 4qdn FLAGELLAR PROTEIN
FLGJ [PEPTIDOGLYCAN
HYDROLASE]
(Thermotoga
maritima) 		4 / 5 LEU A  27
SER A  12
LEU A  46
LEU A  89
 None
 1.06A 4n09B-4qdnA:
undetectable		 4n09B-4qdnA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 4qdn FLAGELLAR PROTEIN
FLGJ [PEPTIDOGLYCAN
HYDROLASE]
(Thermotoga
maritima) 		4 / 5 LEU A  27
SER A  12
LEU A  46
LEU A  89
 None
 1.05A 4n09D-4qdnA:
undetectable		 4n09D-4qdnA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4qdn FLAGELLAR PROTEIN
FLGJ [PEPTIDOGLYCAN
HYDROLASE]
(Thermotoga
maritima) 		5 / 9 GLY A  21
ILE A  26
GLY A  24
LEU A  27
ILE A  49
 None
None
None
None
PO4  A 201 ( 4.6A)
 0.86A 5vkqC-4qdnA:
undetectable
5vkqD-4qdnA:
undetectable		 5vkqC-4qdnA:
6.22
5vkqD-4qdnA:
6.22