SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qe0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FCN_B_DVAB35_0 (UBIQUITIN)	4qe0	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	4 / 6	LEU A 179 GLU A 174 ILE A 173 PRO A 172	None SO4 A 308 (-3.0A) MLY A 171 ( 4.3A) MLY A 171 ( 2.6A)	1.11A	2fcnA-4qe0A: undetectable 2fcnB-4qe0A: undetectable	2fcnA-4qe0A: 17.39 2fcnB-4qe0A: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X7H_A_PFNA1374_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	4qe0	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	4 / 6	PRO A 190 LYS A 121 GLU A 147 TYR A 149	MLY A 189 ( 2.6A) MLY A 120 ( 2.9A) None None	1.38A	2x7hA-4qe0A: undetectable	2x7hA-4qe0A: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MI4_B_SPMB201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	4qe0	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	4 / 7	ASN A 140 GLU A 138 GLU A 161 ARG A 158	None MLY A 68 ( 2.9A) MLY A 165 ( 4.4A) GOL A 301 ( 2.6A)	1.06A	4mi4B-4qe0A: undetectable 4mi4C-4qe0A: undetectable	4mi4B-4qe0A: 23.26 4mi4C-4qe0A: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_B_SPMB201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	4qe0	HYPOTHETICAL PROTEIN (Bacteroides uniformis)	4 / 8	ASN A 140 GLU A 138 GLU A 161 ARG A 158	None MLY A 68 ( 2.9A) MLY A 165 ( 4.4A) GOL A 301 ( 2.6A)	1.05A	4mj8B-4qe0A: undetectable 4mj8C-4qe0A: undetectable	4mj8B-4qe0A: 23.65 4mj8C-4qe0A: 23.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2FCN_B_DVAB35_0","UBIQUITIN","4qe0","HYPOTHETICAL PROTEIN","Bacteroides uniformis",4,"LEU A 179;GLU A 174;ILE A 173;PRO A 172","None;SO4 A 308 (-3.0A);MLY A 171 ( 4.3A);MLY A 171 ( 2.6A)","1.11A","2fcnA-4qe0A:undetectable;2fcnB-4qe0A:undetectable","2fcnA-4qe0A:17.39;2fcnB-4qe0A:17.39"],["2X7H_A_PFNA1374_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","4qe0","HYPOTHETICAL PROTEIN","Bacteroides uniformis",4,"PRO A 190;LYS A 121;GLU A 147;TYR A 149","MLY A 189 ( 2.6A);MLY A 120 ( 2.9A);None;None","1.38A","2x7hA-4qe0A:undetectable","2x7hA-4qe0A:19.45"],["4MI4_B_SPMB201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","4qe0","HYPOTHETICAL PROTEIN","Bacteroides uniformis",4,"ASN A 140;GLU A 138;GLU A 161;ARG A 158","None;MLY A  68 ( 2.9A);MLY A 165 ( 4.4A);GOL A 301 ( 2.6A)","1.06A","4mi4B-4qe0A:undetectable;4mi4C-4qe0A:undetectable","4mi4B-4qe0A:23.26;4mi4C-4qe0A:23.26"],["4MJ8_B_SPMB201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","4qe0","HYPOTHETICAL PROTEIN","Bacteroides uniformis",4,"ASN A 140;GLU A 138;GLU A 161;ARG A 158","None;MLY A  68 ( 2.9A);MLY A 165 ( 4.4A);GOL A 301 ( 2.6A)","1.05A","4mj8B-4qe0A:undetectable;4mj8C-4qe0A:undetectable","4mj8B-4qe0A:23.65;4mj8C-4qe0A:23.65"]]