SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4qfb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		6 / 12 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.67A 1jdvE-4qfbA:
17.4
1jdvF-4qfbA:
17.4		 1jdvE-4qfbA:
25.10
1jdvF-4qfbA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 4qfb CT263
(Chlamydia
trachomatis) 		4 / 5 LEU A  94
VAL A 135
TYR A 124
THR A 118
 None
 1.43A 1nw3A-4qfbA:
undetectable		 1nw3A-4qfbA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 9 GLY A  74
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.52A 1pk7A-4qfbA:
17.3		 1pk7A-4qfbA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		6 / 10 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.48A 1pk7C-4qfbA:
18.2		 1pk7C-4qfbA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		6 / 10 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.45A 1pk9A-4qfbA:
17.4		 1pk9A-4qfbA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 9 GLY A  74
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.51A 1pk9B-4qfbA:
17.3		 1pk9B-4qfbA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		6 / 11 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.39A 1pk9C-4qfbA:
18.1		 1pk9C-4qfbA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 10 GLY A  74
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.55A 1pw7A-4qfbA:
17.4		 1pw7A-4qfbA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 9 VAL A 135
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.48A 1pw7C-4qfbA:
18.2		 1pw7C-4qfbA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 9 PHE A  23
VAL A  42
LEU A   6
SER A 179
LEU A  40
 None
 1.44A 1wrkA-4qfbA:
undetectable
1wrkB-4qfbA:
undetectable		 1wrkA-4qfbA:
18.27
1wrkB-4qfbA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 10 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
 None
 0.56A 1z35A-4qfbA:
17.2		 1z35A-4qfbA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 9 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
 None
 0.50A 1z37A-4qfbA:
17.2		 1z37A-4qfbA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 GLY A  74
VAL A 135
MET A 137
GLU A 138
ASP A 161
 None
 0.37A 2ac7A-4qfbA:
17.0
2ac7B-4qfbA:
17.0		 2ac7A-4qfbA:
20.78
2ac7B-4qfbA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 GLY A  74
VAL A 135
MET A 137
GLU A 138
ASP A 161
 None
 0.37A 2ac7A-4qfbA:
17.0
2ac7B-4qfbA:
17.0		 2ac7A-4qfbA:
20.78
2ac7B-4qfbA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 12 THR A  85
LEU A 114
VAL A  91
ALA A  70
VAL A 106
 None
 1.19A 2g72A-4qfbA:
undetectable		 2g72A-4qfbA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 12 THR A  85
LEU A 114
VAL A  91
ALA A  70
VAL A 106
 None
 1.14A 2g72B-4qfbA:
undetectable		 2g72B-4qfbA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 LEU A  18
ALA A 183
ILE A 156
GLY A  71
VAL A  42
 None
 1.27A 3oxxB-4qfbA:
undetectable		 3oxxB-4qfbA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 12 GLY A  74
VAL A 135
MET A 137
GLU A 138
ASP A 161
 None
 0.51A 3u40B-4qfbA:
17.5
3u40C-4qfbA:
17.3		 3u40B-4qfbA:
26.10
3u40C-4qfbA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 GLY A  74
VAL A 135
MET A 137
GLU A 138
ASP A 161
 None
 0.49A 3u40D-4qfbA:
17.9
3u40E-4qfbA:
17.1		 3u40D-4qfbA:
26.10
3u40E-4qfbA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 12 GLY A  74
VAL A 135
MET A 137
GLU A 138
ASP A 161
 None
 0.47A 3u40D-4qfbA:
17.9
3u40E-4qfbA:
17.1		 3u40D-4qfbA:
26.10
3u40E-4qfbA:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		6 / 11 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.46A 3uawA-4qfbA:
17.8		 3uawA-4qfbA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
 None
 0.50A 4d9hA-4qfbA:
18.5		 4d9hA-4qfbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 GLY A  74
VAL A 135
MET A 137
SER A 160
ASP A 161
 None
 0.97A 4d9hA-4qfbA:
18.5		 4d9hA-4qfbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 9 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
 None
 0.68A 4da6A-4qfbA:
18.0		 4da6A-4qfbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 9 GLY A  74
VAL A 135
MET A 137
SER A 160
ASP A 161
 None
 1.06A 4da6A-4qfbA:
18.0		 4da6A-4qfbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 10 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
 None
 0.55A 4da7A-4qfbA:
18.4		 4da7A-4qfbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
 None
 0.51A 4danA-4qfbA:
18.0		 4danA-4qfbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 GLY A  74
VAL A 135
MET A 137
SER A 160
ASP A 161
 None
 0.91A 4danA-4qfbA:
18.0		 4danA-4qfbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		6 / 12 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
ASP A 161
 None
 0.89A 4danA-4qfbA:
18.0
4danB-4qfbA:
17.9		 4danA-4qfbA:
22.69
4danB-4qfbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 10 THR A  17
ALA A 185
ILE A 109
ALA A  70
ILE A  68
 None
 1.07A 4lbgA-4qfbA:
undetectable		 4lbgA-4qfbA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 9 THR A  17
ALA A 185
ILE A 109
ALA A  70
ILE A  68
 None
 0.96A 4lbgB-4qfbA:
undetectable		 4lbgB-4qfbA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 4qfb CT263
(Chlamydia
trachomatis) 		3 / 3 LEU A  45
LYS A  46
THR A  47
 None
 0.63A 4lj0A-4qfbA:
undetectable		 4lj0A-4qfbA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4qfb CT263
(Chlamydia
trachomatis) 		5 / 11 GLY A  74
VAL A 135
MET A 137
GLU A 138
SER A 160
 None
 0.41A 5i3cC-4qfbA:
17.5		 5i3cC-4qfbA:
20.16